Granulocyte-macrophage colony-stimulating factor potentiates antitumor activity of lnterleukin-12 in melanoma model in mice

Tumor Biology

Volumn 19, Issue 2, 1998, Pages 77-87

  Goła̧b, Jakitb ^a,b,c   Stoktosa, Tomasz ^a   Zagozdzon, Radostaw ^a   Kaca, Aleksandra ^a   Kulchitska, Ludmilaa ^a   Feleszko, Wojciech ^a   Kawiak, Jerzy ^a   Hoser, Grazyna ^a   Gfowacka, Ewa ^a   Dqbrowska, Anna ^a  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

^b ODESSA NATIONAL MEDICAL UNIVERSITY   (Ukraine)

^c MEDICAL CENTER FOR POSTGRADUATE EDUCATION   (Poland)

Author keywords

Immunotherapy; Interleukin 12 granulocyte macrophage colony stimulating factor; Melanoma

Indexed keywords

RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECOMBINANT INTERLEUKIN 12;

ANIMAL CELL; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER IMMUNOTHERAPY; CONTROLLED STUDY; DRUG POTENTIATION; GROWTH INHIBITION; INTRAPERITONEAL DRUG ADMINISTRATION; INTRATUMORAL DRUG ADMINISTRATION; MELANOMA; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; TREATMENT OUTCOME; TUMOR CELL; TUMOR GROWTH;

EID: 0031905393     PISSN: 10104283     EISSN: None     Source Type: Journal    
DOI: 10.1159/000029978     Document Type: Article

References (30)

1. References 1 Trinchieri G: Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu Rev Immunol 1995;13:251276.
2. Chan SH, Kobayashi M, Santoli D, Perussia B, Trinchieri Q: Mechanisms of IFN-Y induction by natural killer cell stimulatory factor (NKSF/ IL-12). Role of transcription and mRNA stability in the synergistic interaction between NKSF and IL2. J Immunol 1992;148:92-98.
3. Chan SH, Perussia B, Gupta JW, Kobayashi M, PospiSil M, Young HA, Wolf SF, Young D, Clark SC, Trinchieri G: Induction of interferon y production by natural killer cell stimulatory factor: Characterization of the responder cells and synergy with other inducers. J Exp Med 1991;173:869-878.
4. Manetti R, Parronchi P, Giudizi MG, Piccini MP, Maggi E, Trinchieri G, Romagnani S: Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Thl)-spccific immune responses and inhibits the development of IL-4 producing Th cells. J Exp Med 1993;177:1199-1204.
5. Nastala CL, Edington HD, McKinney TG, Tahara H, Nalesnik MA, Brunda MJ, Gately MK, Wolf SF, Schreiber RD, Storkus WJ, Lotze MT: Recombinant IL-12 administration induces tumor regression in association with IFN-Y production. J Immunol 1994;153:1697-1706.
6. Brunda MJ, Luistro L, Warner RR, Wright RB, Hubbard BR, Murphy M, Wolf SF, Gately MK: Antitumor and antimetastatic activity of interleukin 12 against murine tumors. J Exp Med 1993;178:1223-I230.
7. Mu J, Zou J-P, Yamamoto N, Tsutsui T, Tai X-G, Kobayashi M, Herrmann S, Fujiwara H, Hamaoka T: Administration of recombinant interleukin 12 prevents outgrowth of tumor cell metastasizing spontaneously to lung and lymph nodes. Cancer Res 1995;55:4404-4408.
8. Brunda MJ, Gately MK: Antitumor activity of interleukin 12. Clin Immunol Immunopathol 1994;71: 253-255.
9. Wigginton JM, Komschlics KL, Back TC, Franco JL, Brunda MJ, Wiltrout RH: Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal carcinoma. J Natl Cancer Inst 1996;88:38-43.
10. Coughlin CM, Wysocka M, Kurzava HL, Lee WMF, Trinchieri G, Eck SL: B7-1 and interleukin 12 synergistically induce effective antitumor immunity. Cancer Res 1995; 55:4980-4987.
11. Eng VM, Car BD, Schnyder B, Lorenz M, Lugli S, Aguet M, Anderson TD, Ryffel B, Quesniaux VFJ: The stimulatory effects of interleukin (IL)-12 on hematopoiesis are antagonized by IL-12-induced interferonY in vivo. J Exp Med 1995;181: 1893-1898.
12. Atkins MB, Robertson MJ, Gordon M, Lotze MT, DeCoste M, DuBois JS, Ritz J, Sandler AB, Edington HD, Garzone PD, Mier JW, Canning CM, Battiato L, Tahara H, Sherman ML: Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies. Clin Cancer Res 1997;3:409-417.
13. Dranoff G, Jaffe E, Lazenby A, Golumbek P, Levitsky H, Brose K, Jackson V, Hamada H, Pardoll D, Mulligan RC: Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and longlasting anti-tumor immunity. Proc Natl Acad Sei USA 1993;90:35393543.
14. Wos E, Olnecki T, Tuason L, Budd GT, Peereboom D, Sandstrom K, McLain D, Finke J, Bikowski RM: Phase II trial of subcutaneously administered recombinant granulocyte-macrophage colony-stimulating factor in patients with metastatic renal cell carcinoma. Cancer 1996; 77:1149-1153.
15. Grabstein KH.Urdal DL, Tushinski RJ, Mochizuki DY, Price VL, Cantrell MA, Gülis S, Conlon PJ: Induction of macrophage tumoricidal activity by granulocyte-macrophage colony-stimulating factor. Science 1986;232:506-507.
16. Kushner BH, Cheung N-KV: GMCSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma. Blood 1989;73: 1936-1941.
17. Wing EJ, Magee DM, Whiteside TL, Kaplan SS, Shadduck RK: Recombinant human granulocyte-macrophage colony-stimulating factor enhances monocyte cytotoxicity and secretion of tumor necrosis factor alpha and interferon in cancer patients. Blood 1989;73:643-646.
18. Sallusto F, Lanzavecchia A: Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony stimulating factor plus interleukin 4 and downregulatcd by tumor necrosis factor a. J Exp Med 1994;179:1109-1118.
19. Lasek W, Warikowicz A, Kuc K, Feleszko W, Golab J, Giermasz A, Wiktor-Jedrzejczak W, Jaköbisiak M: Potentiation of antitumor effects of tumor necrosis factor-a and interferon-Y by macrophage-colony-stimulating factor in a MmBl6 melanoma model in mice. Cancer Immunol Immunother 1995;40:315-321.
20. Lasek W, Warikowicz A, Kuc K, Feleszko W, Giermasz A, Jaköbisiak M: Augmentation of antitumor efficacy by the combination of actinomycin A with tumor necrosis factora and Interferon-Y on a melanoma model in mice. Oncology 1996;53: 31-37.
21. Aruga A, Shu S, Chang AE: Tumorspecific granulocyte/macrophage colony-stimulating factor and interferon Y secretion is associated with in vivo therapeutic efficacy of activated tumor-draining lymph node cells. Cancer Immunol Immunother 1995;41:317-324.
22. Goedegebuure PS, Zuber M, Leonard-Vidal DL, Bürger UL, Cusack JC, Chang MP, Douville LM, Eberlein TJ: Reactivation of murine tumor-infiltrating lymphocytes with solid-phase anti-CD3 antibody: In vitro cytokine production is associated with in vivo efficacy. Surg Oncol 1994;3:79-89.
23. Golumbek PT, Azhari R, Jaffe M, Levitsky HI, Lazcnby A, Leong K, Pardoll DM: Controlled release, biodegradable cytokine depots: A new approach in cancer vaccine design. Cancer Res 1993;53:58415844.
24. Hara I, Takechi Y, Houghton AN: Implicating a role for immune recognition of self in tumor rejection: Passive immunization against the Brown locus protein. J Exp Med 1995;182:1609-16I4.
25. Tsung K, Meko JB, Peplinski OR, Tsung YL, Norton JA: IL-12 induces T helper 1-directed antitumor response. J Immunol 1997;I58: 3359-3365.
26. Metcalf D, Begley GG, Williamson DJ, Nice EC, De Lamarter J, Mermod J-J, Thatcher D, Schmidt A: Hemopoietic responses in mice injected with purified recombinant murine GM-CSF. Exp Hematol 1987;15:l-9.
27. Pojda Z, Molineux G, Dexter TM: Effects of long-term in vivo treatment of mice with purified murine recombinant GM-CSF. Exp Hematol 1989;17:1100-1104.
28. Philips N, Jacobs S, Stoller R, Earle M, Przepiorka M, Shadduck RK: Effect of recombinant human granulocyte-macrophage colony-stimulating factor on myelopoiesis in patients with refractory metastatic carcinoma. Blood 1989;74:26-34.
29. Lieschke GJ, Mäher D, Cebon J, O'Connor M, Green M, Sheridan W, Boyd A, Railings M, Bonnern E, Metcalf D, Burgess AW, McGrath K, Fox RM, Morstyn G: Effects of subcutaneously administered bacterially-synthesized recombinant human granulocyte-macrophage colony-stimulating factor in patients with advanced malignancy. Ann Intern Med 1989;! 10:357-364.
30. Burdach SEG, Müschenich M, Josephs W, Frisch J, Schulz G, Jürgens H, Göbel U: Recombinant human granulocyte-macrophage colonystimulating factor for prevention of neutropenia and infections in children and adolescents with solid tumors. Cancer 1995;76:510-516.