Endothelin: New discoveries and rapid progress in the clinic

Trends in Pharmacological Sciences

Volumn 19, Issue 1, 1998, Pages 5-8

  Webb, D J ^a   Monge, J C ^b   Rabelink, T J ^c   Yanagisawa, M ^d  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF TORONTO   (Canada)

^c UTRECHT UNIVERSITY   (Netherlands)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (2 CARBOXYMETHOXY 4 METHOXYPHENYL) 1 (3,4 METHYLENEDIOXYPHENYL) 5 PROPOXY 2 INDANCARBOXYLIC ACID; ATRASENTAN; BOSENTAN; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIN 1; ENDOTHELIN 2; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR ANTAGONIST; ENDOTHELIN CONVERTING ENZYME; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; NITRIC OXIDE; PROSTACYCLIN; TAK 044;

AMINO ACID SUBSTITUTION; CARDIOVASCULAR DISEASE; CELLULAR DISTRIBUTION; CONFERENCE PAPER; CONGESTIVE HEART FAILURE; HEART VENTRICLE ARRHYTHMIA; HUMAN; HYPERTENSION; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY DISEASE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SITE DIRECTED MUTAGENESIS; VASCULAR ENDOTHELIUM; VASOCONSTRICTION; VASODILATATION;

EID: 0031905118     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(97)01144-9     Document Type: Conference Paper

References (15)

1. Yanagisawa M. et al. Nature. 332:1988;411-415.
2. Inoue A., Yanagisawa M., Kimura S. Proc. Natl. Acad. Sci. U. S. A. 86:1989;2863-2867.
3. Gray G. A., Webb D. J. Pharmacol. Ther. 72:1996;109-148.
4. Haynes W. G. et al. Circulation. 93:1996;1860-1870.
5. Kiowski W. et al. Lancet. 346:1995;732-736.
6. Love M. P. et al. Circulation. 94:1996;2131-2137.
7. Verhaar, M. C. et al. Circulation (in press).
8. Davenport A. P., Maguire J. J. Trends Pharmacol. Sci. 15:1994;9-11.
9. Hosoda K. et al. Cell. 79:1994;1267-1276.
10. Puffenberger E. G. et al. Cell. 79:1994;1257-1266.
11. Sakai S. et al. Nature. 384:1996;353-355.
12. Rabelink T. J. et al. Kidney Int. 50:1996;1827-1833.
13. Kurihara Y. et al. Nature. 368:1994;703-710.
14. Yanagisawa, H. et al. Development (in press).
15. Nelson J. B. et al. Nat. Med. 9:1995;944-949.