Impact of recombinant human growth hormone treatment on psychological profiles in hypopituitary patients with adult-onset growth hormone deficiency

European Journal of Clinical Investigation

Volumn 28, Issue 1, 1998, Pages 13-19

  Giusti, M ^a   Meineri, I ^a   Malagamba, D ^a   Cuttica, C M ^a   Fattacciu, G ^a   Menichini, U ^a   Rasore, E ^a   Giordano, G ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

GH deficiency; IGF I; Psychological evaluation; rh GH; Well being

Indexed keywords

HUMAN GROWTH HORMONE; PLACEBO; SOMATOMEDIN C;

ADENOMA; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GROWTH HORMONE DEFICIENCY; HAMILTON SCALE; HYPOPITUITARISM; MALE; PRIORITY JOURNAL; PROLACTINOMA; PSYCHOLOGIC ASSESSMENT; QUALITY OF LIFE; QUESTIONNAIRE; SUBCUTANEOUS DRUG ADMINISTRATION; SUBSTITUTION THERAPY;

ADULT; AGED; DEPRESSIVE DISORDER; FEMALE; HUMAN GROWTH HORMONE; HUMANS; HYPOPITUITARISM; INSULIN-LIKE GROWTH FACTOR I; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PERSONALITY INVENTORY;

EID: 0031905017     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.1998.00239.x     Document Type: Article

References (36)

1. Cuneo RC, Salomon GA, McGauley GA, Sonksen PH. The growth hormone deficiency syndrome in adults. Clinical Endocrinology, 1992; 37: 387-397.
2. De Boer H, Blok G-J, Van Der Veen EA. Clinical aspects of growth hormone deficiency in adults. Endocrine Review, 1995; 16: 63-86.
3. Attanasio AF, Lamberts SWJ, Matranga AMC et al. Adult growth hormone (GH)-deficient patients demonstrate heterogeneity between childhood onset and adult onset before and during human GH treatment. Journal of Clinical Endocrinology and Metabolism, 1997; 82: 82-88.
4. Bengtsson B-A, Eden S, Lonn L, Kvist H et al. Treatment of adults with growth hormone (GH) deficiency with recombinant human GH. Journal of Clinical Endocrinology and Metabolism, 1993; 76: 309-317.
5. Bronstein MD, Musolino NCR, Cunha Neto MB et al. Impact of treatment with growth hormone on the psychological and somatic profile of adults with growth hormone deficiency. Endocrinology and Metabolism, 1997; 4 (Suppl. B): 168.
6. Burman P, Broman JE, Hetta J et al. Quality of life in adults with growth hormone (GH) deficiency: response to treatment with recombinant human GH in a placebo-controlled 21-month trial. Journal of Clinical Endocrinology and Metabolism, 1995; 80: 3585-3590.
7. Holmes SJ, Shalet SM. Factors influencing the desire for long-term growth hormone replacement in adults. Clinical Endocrinology, 1995; 43: 151-157.
8. Mc Gauley GA, Cuneo RC, Salomon F, Sonksen PH. Psychological well-being before and after growth hormone treatment in adults with growth hormone deficiency. Hormone Research, 1990; 33 (suppl. 4): 52-54.
9. Whitehead HM, Boreham C, Mcllrath EM et al. Growth hormone treatment of adults with growth hormone deficiency: results of a 13-month placebo controlled crossover study. Clinical Endocrinology, 1992; 36: 45-52.
10. Johansson J-O, Larson G, Andersson M et al. Treatment of growth hormone-deficient adults with recombinant human growth hormone increases the concentration of growth hormone in the cerebrospinal fluid and affects neurotransmitters. Neuroendocrinology, 1995; 61: 57-66.
11. Janssen VJH, Frolich M, Roelfsema F. A low starting dose of genotropin in growth hormone deficient adults. Journal of Clinical Endocrinology and Metabolism, 1997; 82: 129-135.
12. Giusti M, Sanna R, Aglialoro A et al. Clinical effects of low doses of growth hormone in hypopituitary patients with adult-onset growth hormone deficiency. Endocrinology and Metabolism, 1997; 4 (Suppl. B): 165.
13. Hoffman DM, O'Sullivan AJ, Baxter RC, Ho KKY. Diagnosis of growth-hormone deficiency in adults. Lancet, 1994; 43: 1064-1068.
14. De Boer H, Blok G-J, Voerman B, De Vries P, Popp-Snijders C, Der Veen E. The optimal growth hormone replacement dose in adults, derived from bioimpedance analysis. Journal of Clinical Endocrinology and Metabolism, 1995; 80: 2069-2076.
15. Fava G, Kellner R. Versione italiana del symptom questionnaire (SQ) di Kellner. In: Canestrari R, ed. Nuovi Metodi in Psicometria. Firenze: Organizzazioni Speciali, 1982: 51-64.
16. Kellner R. Part 1. Improvement criteria drug trials with neurotic patients. Psychological Medicine, 1971; 1: 416-421.
17. Hamilton M. A rating scale for depression. Journal of Neurosurgery and Psychiatry, 1960; 23: 56-59.
18. Barreca A, Ciccarelli E, Minuto F, Bruzzi P, Giordano G, Camanni F. Insulin-like growth factor I and daily growth hormone profile in the assessment of active acromegaly. Acta Endocrinologica, 1989; 120: 629-635.
19. Giusti M, Marini G, Lomeo A et al. Effect of aging on growth hormone (GH) responsiveness to GH-releasing hormone (GHRH) in man: Correlation with thyroid hormones, testosterone, and somatomedin-C levels. Hormones and Metabolism, 1989; 3: 73-97.
20. Raben MS. Clinical use of growth hormone. New England Journal of Medicine, 1962; 266: 82-86.
21. Jorgensen JOL, Pedersen SA, Thuesen L et al. Beneficial effects of growth hormone treatment in GH-deficient adults. Lancet, 1989; 1: 1221-1225.
22. Salomon F, Cuneo RC, Hesp R, Sonksen PH. The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. New England Journal of Medicine, 1989; 321: 1797-1803.
23. Wallymahmed ME, Baker GA, Humphris G, Dewey M, MacFarlane IA. The development, reliability and validity of a disease specific quality of life model for adults with growth hormone deficiency. Clinical Endocrinology, 1996; 44: 403-411.
24. Ormel J, Sanderman A. Life events, personal control and depression. In: Steptoe A, Appels A, eds. Stress, Personal Control and Depression. Chichester: John Wiley, 1989: 193-213.
25. Stabler B. Growth hormone insufficiency during childhood implications for later life. Acta Pediatrica Scandinavica 1992 377 (suppl.): 9-13.
26. Burman P, Hetta J, Wide I, Mansson J-E, Ekman R, Karlsson FA. Growth hormone treatment affects brain neurotransmitters and thyroxine. Clinical Endocrinology, 1996; 44: 319-324.
27. Lai Z, Emtner M, Ross P, Nyberg F. Characterization of putative growth hormone receptors in human choroid plexus. Brain Research, 1991; 546: 222-226.
28. Risby ED, Hsiao JK, Sunderland T, Agren H, Rudorfer MV, Potter WZ. The effects of antidepressants on the cerebrospinal fluid homovanilic acid/5-hydroxyndolcacetic acid ratio. Clinical Pharmacology and Therapeutics, 1987; 42: 547-554.
29. Hayman SE, Nesler EJ. The Molecular Functions of Psychiatry. Washington DC: American Psychiatric Press 1993: 56-135.
30. Gardner D. Synaptic transmission. In: Conn PM, ed. Neuroscience in Medicine. Philadelphia: J.B. Lippincott, 1995: 75-114.
31. Oertel H, Stalla GK, Uhl E, Holsboer F, Zihl J. The effect of growth hormone replacement on cognitive performance in adult hypopituitary patients with growth hormone deficiency (GHD). Journal of Endocrinological Investigation, 1996; 19 (Suppl. to no. 5): 28.
32. Wang C, Alexander G, Herman N et al. Testosterone replacement therapy improves mood in hypogonadal men. A clinical research center study. Journal of Clinical Endocrinology and Metabolism, 1996; 81: 3578-3583.
33. Hennessey JV, Jackson IMD. The interface between thyroid hormones and psychiatry. Endocrinologist, 1996; 6: 214-223.
34. Jorgensen JOL, Weeke J. Growth hormone administration stimulates extrathyroidal conversion of thyroxine to triiodothyronine: possible physiological implications. In: Juul A, Jorgensen JOL, eds. Growth Hormone in Adults, Physiological and Clinical Aspects. Cambridge: Cambridge University Press, 1996: 295-306.
35. Wolf M, Ingbar SH, Moses AC. Thyroid hormones and growth hormone interact to regulate insulin-like growth factor-I messenger ribonucleic acid and circulating levels in the rat. Endocrinology, 1989; 125: 2905-2914.
36. Johnston DG. Growth hormone deficiency and quality of life in hypopituitary adults (commentary). Clinical Endocrinology, 1997; 46: 407-408.