Expression and initial characterization of recombinant antiacetylcholine receptor antibodies in experimental autoimmune myasthenia gravis

Annals of the New York Academy of Sciences

Volumn 841, Issue , 1998, Pages 466-468

  Kirvan, Christine A ^a   Zhu, Shan ^a   Richman, David P ^a   Agius, Mark A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINERGIC RECEPTOR ANTIBODY; COMPLEMENT; COMPLEMENTARY DNA; IMMUNOGLOBULIN HEAVY CHAIN; RECOMBINANT PROTEIN; RNA;

ANIMAL CELL; AUTOIMMUNE DISEASE; COMPLEMENT ACTIVATION; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE AMPLIFICATION; GENETIC TRANSFECTION; MYASTHENIA GRAVIS; NONHUMAN; RAT; RNA SPLICING;

ANIMALIA;

EID: 0031904126     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1998.tb10963.x     Document Type: Conference Paper

References (3)

1. BRUGGEMANN, M., C. TEALE, M. CLARK, C. BINDON & H. WALDMANN. 1989. A matched set of rat/mouse chimeric antibodies: identification and biological properties of rat H chain constant regions mu, gamma 1, gamma 2a, gamma 2b, gamma 2c, epsilon, and alpha. J. Immunol. 142: 3145-3150.
2. AGIUS, M. A., C. J. GEANNOPOULOS, R. H. FAIRCLOUGH & D. P. RICHMAN. 1988. Monoclonal antiidiotopic antibodies against myasthenia-inducing anti-acetylcholine receptor monoclonal antibodies: preponderance of nonparatope-directed antibodies affecting antigen binding. J. Immunol. 140: 62-68.
3. BLAIR, D. A., M. MIHOVILOVIC, M. A. AGIUS, R. H. FAIRCLOUGH & D. P. RICHMAN. 1987. Human x human hybridomas from patients with myasthenia gravis: possible tools for idiotypic therapy for myasthenia. Ann. N.Y. Acad. Sci. 505: 155-167.