Human COL9A1 and COL9A2 genes. Two genes of 90 and 15 kb code for similar polypeptides of the same collagen molecule

Matrix Biology

Volumn 17, Issue 3, 1998, Pages 237-241

  Pihlajamaa, Tero ^a   Vuoristo, Mirka M ^a   Annunen, Susanna ^a   Perälä, Merja ^a,b   Prockop, Darwin J ^c   Ala Kokko, Leena ^a,c  

^a UNIVERSITY OF OULU   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Cartilage; Collagen

Indexed keywords

COLLAGEN TYPE 9;

ARTICLE; CHICKEN; CONTROLLED STUDY; DNA SEQUENCE; EXON; GENE; GENE STRUCTURE; HUMAN; INTRON; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT;

GALLUS GALLUS;

EID: 0031903619     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(98)90063-4     Document Type: Article

References (14)

1. Diab, M., Wu, J.J. and Eyre, D.: Collagen type IX from human cartilage: a structural profile of intermolecular cross-linking sites. Biochem. J. 314: 327-332, 1996.
2. Muragaki, Y., Kimura, T., Ninomiya, Y. and Olsen, B.R.: The complete primary structure of two distinct forms of human α1(IX) collagen chains. Eur. J. Biochem. 192: 703-708, 1990a.
3. Muragaki, Y., Mariman, E.G.M., van Beersum, S.E.C., Perälä, M., van Mourik, J.B.A., Warman, M.L., Olsen, B.R. and Hamel, B.C.J.: A mutation in the gene encoding the α2 chain of the fibril-associated collagen IX, COL9A2, causes multiple epiphyseal dysplasia (EDM2). Nat. Genet. 12: 103-105, 1996.
4. Muragaki, Y., Nishimura, I., Henney, A., Ninomiya, Y. and Olsen, B.R.: The α1(IX) collagen gene gives rise to two different transcripts in both mouse embryonic and human fetal RNA. Proc. Natl. Acad. Sci. USA 87: 2400-2404, 1990b.
5. Nishimura, I., Muragaki, Y. and Olsen, B.R.: Tissue-specific forms of type IX collagen-proteoglycan arise from the use of two widely separated promoters. J. Biol. Chem. 264: 20033-20041, 1989.
6. Perälä, M., Elima, K., Metsäranta, M., Rosati, R., de Crombrugghe, B. and Vuorio, E.: The exon structure of the mouse α2(IX) collagen gene shows unexpected divergence from the chick gene. J. Biol. Chem. 269: 5064-5071, 1994.
7. Perälä, M., Hänninen, M., Hästbacka, J., Elima, K. and Vuorio, E.: Molecular cloning of the human α2(IX) collagen cDNA and assignment of the human COL9A2 gene to chromosome 1. FEBS Lett. 319: 177-180, 1993.
8. Pierce, J.C. and Sternberg, N.: Using the bacteriohage P1 system to clone high molecular weight (HMW) genomic DNA. Meth. Enzymol. 216: 549-574, 1992.
9. Shaw, L.M. and Olsen, B.R.: Collagens in the FACIT group. Diverse molecular bridges in extracellular matrices. Trends Biochem. Sci 16: 191-194, 1991.
10. Ting, K., Petropulos, L.A., Iwatsuki, M. and Nishimura, I.: Altered cartilage phenotype expressed during intramembranous bone formation. J. Bone Min. Res. 8: 1377-1387, 1993.
11. van der Rest, M. and Mayne, R.: Type IX collagen. In: Structure and Function of Collagen Types, ed. by Mayne, R. and Burgeson, R.E., Academic Press, Orlando, 1987, pp. 195-221.
12. Vikkula, M., Metsäranta, M., Syvänen, A.-C., Ala-Kokko, L., Vuorio, E. and Peltonen, L.: Structural analysis of the regulatory elements of the type II collagen gene: Conservation of promoter and first intron sequences between human and mouse. Biochem. J. 285: 287-294, 1992.
13. Vuoristo, M.M., Pihlajamaa, T., Vandenberg, P., Prockop, D.J. and Ala-Kokko, L.: The human COL11A2 gene structure indicates that the gene has not evolved with the genes for the major fibrillar collagens. J. Biol. Chem. 270: 22873-22881, 1995.
14. Wieringa, B., Hofer, E. and Weissmann, C.: A minimal intron length but no specific internal sequence is required for splicing the large rabbit β-globin intron. Cell 37: 915-925, 1984.