Molecular analysis of 1p36 breakpoints in two merkel cell carcinomas

Genes Chromosomes and Cancer

Volumn 23, Issue 1, 1998, Pages 67-71

  Van Gele, M ^a   Van Roy, N ^a   Ronan, S G ^b   Messiaen, L ^a   Vandesompele, J ^a   Geerts, M L ^a   Naeyaert, J M ^a   Blennow, E ^c   Bar Am, I ^d   Das Gupta, T K ^b   Van Der Drift, P ^f   Versteeg, R ^f   Leonard, J H ^e   Speleman, Frank ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d Applied Spectral Imaging Ltd   (Israel)

^e Queensland Radium Institute   (Australia)

^f University Hospital Gent ^*

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 1; CHROMOSOME BREAKAGE; CYTOGENETICS; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DELETION; GENE MAPPING; KARYOTYPE; NEUROBLASTOMA; PRIORITY JOURNAL;

AGED; AGED, 80 AND OVER; CARCINOMA, MERKEL CELL; CHROMOSOME ABERRATIONS; CHROMOSOME BANDING; CHROMOSOME DISORDERS; CHROMOSOME FRAGILITY; CHROMOSOMES, HUMAN, PAIR 1; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS; SKIN NEOPLASMS; TUMOR CELLS, CULTURED;

UNIDENTIFIED AGENTS;

EID: 0031903314     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(199809)23:1<67::AID-GCC10>3.0.CO;2-B     Document Type: Article

References (16)

1. Buyse IM, Shao G, Huang S (1995) The retinoblastoma protein binds to RIZ, a zinc finger protein that shares an epitope with the adenovirus E1A protein. Proc Natl Acad Sci USA 92:4467-4471.
2. Caron H, Peter M, van Sluis P, Speleman F, de Kraker J, Laureys G, Michon J, Brugières L, Voûte PA, Westerveld A, Slater R, Versteeg R (1995) Evidence for two tumour suppressor loci on chromosomal bands 1p35-36 involved in neuroblastomas: One probably imprinted, another associated with N-myc amplification. Hum Mol Genet 4:535-539.
3. Gibas Z, Weil S, Chen ST, McCue PA (1994) Deletion of chromosome arm 1p in a Merkel cell carcinoma (MCC). Genes Chromosomes Cancer 9:216-220.
4. Harnett PR, Kearsley JH, Hayward NK, Dracopoli NC, Kefford RF (1991) Loss of allelic heterozygosity on distal chromosome 1p in Merkel cell carcinoma. A marker of neural crest origins? Cancer Genet Cytogenet 54:109-113.
5. Kaghad M, Bonnet H, Yang A, Creancier L, Biscan JC, Valent A, Minty A, Chalon P, Lelias JM, Dumont X, Ferrara P, McKeon F, Caput D (1997) Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 90:809-819.
6. Laureys G, Speleman F, Versteeg R, van der Drift P, Chan A, Leroy J, Francke U, Opdenakker G, Van Roy N (1995) Constitutional translocation (1;17)(p36.31-p36.13;q11.2-q12.1) in a neuroblastoma patient. Establishment of PND/A12M2 on chromosome 1 and NF1/SCYA7 on chromosome 17 as breakpoint flanking single copy markers. Oncogene 10:1087-1093.
7. Leonard JH, Hayward N (1997) Loss of heterozygosity of chromosome 13 in Merkel cell carcinoma. Genes Chromosomes Cancer 20:93-97.
8. Leonard JH, Williams G, Walters MK, Nancarrow DJ, Rabbits PH (1996) Deletion mapping of the short arm of chromosome 3 in Merkel cell carcinoma. Genes Chromosomes Cancer 15:102-107.
9. Ronan SG, Green AD, Shilkaitis A, Huang TSW, Das Gupta TK (1993) Merkel cell carcinoma: In vitro and in vivo characteristics of a new cell line. J Am Acad Dermatol 29:715-722.
10. Schleiermacher G, Peter M, Michon J, Hugot JP, Vielh P, Zucker JM, Magdelénat H, Thomas G, Delattre O (1994) Two distinct regions on the short arm of chromosome 1 in neuroblastoma. Genes Chromosomes Cancer 10:275-281.
11. Schwab M, Praml C, Amler LC (1996) Genomic instability in 1p and human malignancies. Genes Chromosomes Cancer 16:211-229.
12. Toker C (1972) Trabecular carcinoma of the skin. Arch Dermatol 105:107-110.
13. van der Drift P, Chan A, Van Roy N, Laureys G, Westerveld A, Speleman F, Versteeg R (1994) A multimegabase cluster of snRNA and tRNA genes on chromosome 1p36 harbours an adenovirus/ SV40 hybrid virus integration site. Hum Mol Genet 3:2131-2136.
14. van der Drift P, Chan A, Laureys G, Van Roy N, Sickmann G, den Dunnen J, Westerveld A, Speleman F, Versteeg R (1995) Balanced translocation in a neuroblastoma patient disrupts a cluster of small nuclear RNA U1 and tRNA genes in chromosomal band 1p36. Genes Chromosomes Cancer 14:35-42.
15. Van Roy N, Laureys G, Cheng NC, Willem P, Opdenakker G, Versteeg R, Speleman F (1994) 1:17 Translocations and other chromosome 17 rearrangements in human primary neuroblastoma tumors and cell lines. Genes Chromosomes Cancer 10:103-114.
16. Versteeg R, Caron H, Cheng NC, van der Drift P, Slater R, Westerveld A, Voute PA, Delattre O, Laureys G, Van Roy N, Speleman F (1995) 1p36: Every subband a suppressor? Eur J Cancer 31:538-541.