High-dose cladribine therapy for chronic myelogenous leukemia in the accelerated or blast phase

Journal of Clinical Oncology

Volumn 16, Issue 4, 1998, Pages 1498-1504

  Dann, Eldad J ^a   Anastasi, John ^a   Larson, Richard A ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUSULFAN; CLADRIBINE; CYCLOPHOSPHAMIDE; CYTARABINE; ETOPOSIDE; IDARUBICIN; METHOTREXATE; VINCRISTINE;

ADULT; AGED; ALLOGENIC BONE MARROW TRANSPLANTATION; ARTICLE; BLAST TRANSFORMATION; BONE MARROW APLASIA; CANCER COMBINATION CHEMOTHERAPY; CANCER PALLIATIVE THERAPY; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG MEGADOSE; FEMALE; FEVER; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LENGTH OF STAY; LEUKOCYTE COUNT; LYMPHOPROLIFERATIVE DISEASE; MALE; NEUTROPENIA; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; REMISSION; SEPSIS; SURVIVAL TIME; THROMBOCYTE COUNT;

EID: 0031901764     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1998.16.4.1498     Document Type: Article

References (22)

1. Piro LD, Carrera CJ, Carson DA, et al: Lasting remission in hairy cell leukemia induced by a single infusion of 2-chlorodeoxy-adenosine. N Engl J Med 322:1117-1121, 1990
2. Piro LD, Carrera CJ, Beutler E, et al: 2-Chlorodeoxyadenosine: An effective new agent for the treatment of chronic lymphocytic leukemia. Blood 72:1069-1073, 1988
3. Liliemark J, Juliusson G: On the pharmacokinetics of 2-chloro-2′-deoxyadenosine in humans. Cancer Res 51:5570-5572, 1991
4. Vahdat L, Wong ET, Wile MJ, et al: Therapeutic and neurotoxic effects of 2-chlorodeoxyadenosine in adults with acute myeloid leukemia. Blood 84:3429-3434, 1994
5. Cheson BD, Veda DA, Foss FM, et al: Neurotoxicity of purine analogues: A review. J Clin Oncol 12:2216-2228, 1994
6. Larson RA, Mick R, Spielberger RT, et al: Dose-escalation trial of cladribine using five daily intravenous infusions in patients with advanced hematologic malignancies. J Clin Oncol 14:188-195, 1996
7. Snedecor GW, Cochran WG: Statistical Methods (ed 8). Ames, IA, Iowa State University, 1989, p 503
8. Saven A, Piro LD, Lemon RH, et al: Complete hematologic remissions in chronic phase, Philadelphia-chromosome-positive, chronic myelogenous leukemia after 2-chlorodeoxyadenosine. Cancer 73:2953-2963, 1994
9. Canellos GP, DeVita VT, Whang-Peng J, et al: Hematologic and cytogenetic remission of blastic transformation in chronic granulocytic leukemia. Blood 38:671-679, 1971
10. Marks SM, Baltimore D, McCaffrey R: Terminal transferase as a predictor of initial responsiveness to vincristine and prednisone in blastic chronic myelogenous leukemia. N Engl J Med 298:812-814, 1978
11. Winton EF, Miller D, Vogler WR: Intensive chemotherapy with daunorubicin, 5-azacytidine, 6-thioguanine, and cytarabine (DATA) for the blastic transformation of chronic granulocytic leukemia. Cancer Treat Rep 65:389-392, 1981
12. Coleman M, Silver RT, Pajak TF, et al: Combination chemotherapy for terminal-phase chronic granulocytic leukemia: Cancer and Leukemia Group B studies. Blood 55:29-36, 1980
13. Spiers ASD: The management of chronic myelocytic leukemia, in Henderson ES, Lister TA (eds): Leukemia (ed 5). Philadelphia, PA, Saunders, 1990, pp 515-544
14. Hoyle C, Gray R, Goldman J: Autografting for patients with CML in chronic phase: An update. Br J Haematol 86:76-81, 1994
15. Bhatia R, Verfaillie CM, Miller JS, et al: Autologous transplantation therapy for chronic myelogenous leukemia. Blood 89:2623-2634, 1997
16. Reiffers J, Trouette R, Marit G, et al: Autologous blood stem cell transplantation for chronic granulocytic leukaemia in transformation: A report of 47 cases. Br J Haematol 77:339-345, 1991
17. Talpaz M, Kantarjian H, Liang J, et al: Percentage of Philadelphia chromosome (Ph-negative and Ph-positive) cells found after autologous transplantation for chronic myelogenous leukemia depends on percentage of diploid cells induced by conventional-dose chemotherapy before collection of autologous cells. Blood 85:3257-3263, 1995
18. McGlave PB, De Fabritiis P, Deisseroth A, et al: Autologous transplants for chronic myelogenous leukaemia: Results from eight transplant groups. Lancet 343:1486-1488, 1994
19. + lymphocyte counts in patients with hairy cell leukemia. Blood 83:2906-2911, 1994
20. Juliusson G, Lenkei R, Liliemark J: Flow cytometry of blood and bone marrow cells from patients with hairy cell leukemia: Phenotype of hairy cells and lymphocyte subsets after treatment with 2-chlorodeoxyadenosine. Blood 83:3672-3681, 1994
21. Dann EJ, Gillis S, Polliack A, et al: Brief report: Tumor lysis syndrome following treatment with 2-chlorodeoxyadenosine for refractory chronic lymphocytic leukemia. N Engl J Med 329:1547-1548, 1993
22. Trendle MC, Tefferi A: Tumor lysis syndrome after treatment of chronic lymphocytic leukemia with cladribine. N Engl J Med 330:1090, 1994 (letter)