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Mandel JS, Bond JH, Church TR, Snover DC, Bradley GM, Schuman LM, et al. Reducing mortality from colorectal cancer by screening for faecal occult blood. Minnesota Colon Cancer Control Study. N Engl J Med 1993; 328:1365-1371. Annual screening with rehydrated Hemoccult decreases mortality on an intention-to-screen basis by 33% but with a high positivity rate and subsequent colonoscopy in over 30% of screenees at some time during the 13 year follow-up period.
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Hardcastle JD, Bennett DH, Whynes DK. Mass screening: European/ UK perspective. In: Prevention and early detection of colorectal cancer. Young GP, Rozen P, Levin B (editors). London: Saunders; 1996. pp. 275-288.
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St John DJ, Young GP, Alexeyeff MA, Deacon MC, Cuthbertson AM, Macrae FA, et al.: Evaluation of new occult blood tests for detection of colorectal neoplasia. Gastroenterology. 1993; 104:1661-1668. Example of preliminary comparison of different occult blood tests prior to considering use in screenees.
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Young GP, St John DJB, Rose IS, Blake D. Haem in the gut, II. Faecal excretion of haem and haem-derived porphyrins and their detection. J Gastroenterol Hepatol 1990; 5:194-203.
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Young GP, Macrae FA, St John DJB. Clinical methods for early detection: Basis, use and evaluation. In: Prevention and early detection of colorectal cancer. Young GP, Rozen P, Levin B (editors). London: Saunders; 1996. pp. 241-270. Extensive review of screening tests, biology of bleeding and usage of faecal occult blood tests.
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Young GP, St John DJB. Faecal occult blood tests: choice, usage and clinical applications. Clin Biochem Rev 1992; 13:161-167. Review of biochemical basis of faecal occult blood tests.
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Comparison of the specificity and sensitivity of Hemoccult and HemoQuant in screening for colorectal neoplasia
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St John DJB, Young GP, McHutchison JG, Deacon MC, Alexeyeff MA. Comparison of the specificity and sensitivity of Hemoccult and HemoQuant in screening for colorectal neoplasia. Ann Intern Med 1992; 117:376-382.
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Ahlquist DA, McGill DB, Schwartz S, Taylor WF, Ellefson M, Owen RA. HemoQuant, a new quantitative assay for faecal haemoglobin. Comparison with Hemoccult. Ann Intern Med 1984; 101:297-302.
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Simon JB. Occult blood screening for colorectal carcinoma: a critical review. Gastroenterology 1985; 88:820-387.
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Gastrointestinal blood loss from a new buffered aspirin (Ostoprin): Measurement by radiochromium and HemoQuant™ techniques
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Lynch NM, McHutchison JG, Young GP, Deacon M, St John DJB, Barraclough D. Gastrointestinal blood loss from a new buffered aspirin (Ostoprin): measurement by radiochromium and HemoQuant™ techniques. Aust NZ J Med 1989; 19:89-96.
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Iwase T. The evaluation of an immunochemical occult blood test by reversed passive haemagglutination compared with Hemoccult II in screening for colorectal cancer. In: Faecal occult blood tests. Young GP, Saito H (editors). San Jose, CA. SmithKline Diagnostics; 1992. pp. 90-95.
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