Differentiation, proliferation and apoptosis levels in human leiomyoma and leiomyosarcoma

Journal of Cancer Research and Clinical Oncology

Volumn 124, Issue 2, 1998, Pages 93-105

  Valenti, Maria Teresa ^a   Azzarello, Giuseppe ^a   Vinante, Orazio ^a   Manconi, Riccardo ^a   Balducci, Elena ^a   Guidolin, Diego ^b   Chiavegato, Angela ^d   Sartore, Saverio ^c  

^a ULSS 13   (Italy)

^b Fidia Advanced Biopolymers   (Italy)

^c UNIVERSITY OF PADOVA   (Italy)

^d University of Padua ^*

Author keywords

Leiomyoma; Leiomyosarcoma; Myosin isoforms; Smooth muscle cells

Indexed keywords

CELL MARKER;

ANTIBODY SPECIFICITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; DISEASE ASSOCIATION; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; LEIOMYOMA; LEIOMYOSARCOMA; METASTASIS; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; SMOOTH MUSCLE FIBER;

AGED; ANALYSIS OF VARIANCE; APOPTOSIS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL DIVISION; DENSITOMETRY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GASTROINTESTINAL NEOPLASMS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; LEIOMYOMA; LEIOMYOSARCOMA; LIVER NEOPLASMS; MALE; MIDDLE AGED; MYOSIN HEAVY CHAINS; PROLIFERATING CELL NUCLEAR ANTIGEN; UTERINE NEOPLASMS;

EID: 0031900547     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004320050140     Document Type: Article

References (44)

1. Azumi N, Ben-Ezra J, Battifora H (1988) Immunophenotypic diagnosis of leiomyosarcomas and rhabdomyosarcomas with monoclonal antibodies to muscle-specific actin and desmin in formalin-fixed tissue. Mod Pathol 1:469-74
2. Azzarello G, Sartore S, Saggin L, Gorza L, D'Andrea E, Chieco-Bianchi L, Schiaffino S (1987) Myosin isoform expression in rat rhabdomyosarcoma induced by Moloney murine sarcoma virus. J Cancer Res Clin Oncol 113:417-429
3. Bell SW, Kempson RL, Hendrickson MR (1994) Problematic uterine smooth muscle neoplasms. A clinicopathologic study of 213 cases. Am J Surg Pathol 18:535-558
4. Bochaton-Piallat ML, Ropraz P, Gabbiani F, Gabbiani G (1996) Phenotypic heterogeneity of rat arterial smooth muscle cell clones: implications for the development of experimental intimal thickening. Arterioscler Thromb Vasc Biol 16:815-820
5. Borrione AC, Zanellato AMC, Saggin L, Mazzoli M, Azzarello G, Sartore S (1988) Neonatal myosin heavy chains are not expressed in Ni-induced rat rhabdomyosarcoma. Differentiation 38:49-59
6. Borrione AC, Zanellato AMC, Scannapieco G, Pauletto P, Sartore S (1989) Myosin heavy chain isoforms in adult and developing rabbit vascular smooth muscle. Eur J Biochem 183:413-417
7. Borrione AC, Zanellato AMC, Scannapieco G, Giuriato L, Scannapieco G, Pauletto P, Sartore S (1990) Nonmuscle and smooth muscle myosin isoforms in bovine endothelial cell. Exp Cell Res 190:1-10
8. Bosman FT, Visser BC, Oeveren J van (1996) Apoptosis: pathophysiology and programmed cell death. Pathol Res Pract 192:676-683
9. Brooks JJ (1989) Disorders of soft tissue. In: Sternberg SS (ed) Diagnostic surgical pathology. Raven, New York, pp 141-200
10. Capriani A, Chiavegato A, Franch R, Azzarello G, Vinante O, Sartore S (1997) Oestrogen-dependent expression of SM2 smooth-muscle type myosin isoform in rabbit myometrium. J Muscle Res Cell Motil 18:413-427
11. Cavaillé F, Fournier T, Dallot E, Dhellemes C, Ferrè F (1995) Myosin heavy chain isoform expression in human myometrium: presence of an embryonic nonmuscle isoform in leiomyomas and in cultured cells. Cell Motil Cytoskel 30:183-193
12. Chiavegato A, Scatena M, Roelofs M, Ferrarese P, Pauletto P, Passerini-Glazel G, Pagano F, Sartore S (1993) Cytoskeletal and cytocontractile protein composition of smooth muscle cells in developing and obstructed rabbit bladder. Exp Cell Res 207:310-320
13. Chiavegato A, Bochaton-Piallat M-L, D'Amore E, Sartore S, Gabbiani G (1995) Expression of myosin heavy chain isoforms in mammary epithelial cells and in myofibroblasts from different settings during neoplasia. Virchows Arch [B] 426:77-86
14. Chiavegato A, Capriani A, Azzarello G, Vinante O, Pauletto P, Sartore S (1996a) Expression of non-muscle myosin isoforms in rabbit myometrium is estrogen dependent. Cell Tissue Res 283:7-18
15. Chiavegato A, Pauletto P, Sartore S (1996b) Smooth muscle-type myosin heavy chain isoforms in bovine smooth muscle and non-muscle tissues. Biol Cell 86:27-38
16. Cooper CS (1993) The molecular and genetic characterization of human soft tissue tumors. Adv Cancer Res 60:75-120
17. Donner L, de Lanerolle P, Costa J (1983) Immunoreactivity of paraffin-embedded normal tissues and mesenchymal tumors for smooth muscle myosin. Am J Clin Pathol 80:677-681
18. Duband J-L, Gimona M, Scatena M, Sartore S, Small JV (1993) Calponin and SM22 as differentiation markers of smooth muscle: spatiotemporal distribution during avian embryonic development. Differentiation 55:1-11
19. Giuriato L, Scatena M, Chiavegato A, Tonello M, Scannapieco G, Pauletto P, Sartorte S (1992) Non-muscle myosin isoforms and cell heterogeneity in developing rabbit vascular smooth muscle. J Cell Sci 101:233-246
20. Hashimoto H, Daimaru Y, Tsuneyoshi M, Enjoji M (1986) Leiomyosarcoma of the external soft tissues. A clinicopathologic, immuno-histochemical and electron microscopic study. Cancer 57:2077-2088
21. Kawamoto S, Adelstein RS (1991) Chicken non-muscle myosin heavy chains: differential expression of two mRNAs and evidence for two different polypeptides. J Cell Biol 112:915-924
22. Li L, Olson EN (1992) Regulation of muscle cell growth and differentiation by the MyoD family of helix-loop-helix proteins. Adv Cancer Res 58:95-119
23. Maione R, Amati P (1997) Interdependence between muscle differentiation and cell-cycle control. Biochim Biophys Acta 1332:M19-M30
24. Majno G, Joris (1995) Apoptosis, oncosis and necrosis: an overview of cell death. Am J Pathol 146:3-15
25. Miano JM, Cserjesi P, Ligon KL, Perisamy M, Olson EN (1994) Smooth muscle myosin heavy chain exclusively marks the smooth muscle lineage during mouse embryogenesis. Circ Res 75:803-812
26. Miettinen M, Letho V, Badley R, Virtanen I (1982) Expression of intermediate filaments in soft tissue sarcomas. Int J Cancer 30:541-546
27. Moroianu J, Fett JW, Riordan JF, Vallee BL (1993) Actin is a surface component of calf pulmonary artery endothelial cells in culture. Proc Natl Acad Sci USA 90:3815-3819
28. Nanni P, Azzarello G, Tessarollo L, DeGiovanni C, Lollini P-L, Nicoletli G, Scotland K, Landuzzi L, Panozzo M, D'Andrea E, Chieco-Bianchi L, Schiaffino S (1991) In vitro differentiation of rhabdomyosarcomas induced by nickel or by Moloney murine sarcoma virus. Br J Cancer 63:736-742
29. Owens GK (1995) Regulation of differentiation of vascular smooth muscle cells. Physiol Rev 75:487-517
30. Oyama T, Watanabe H, Iwafuchi M, Maejima T, Ajioka Y (1993) Diagnostic value of proliferating cell nuclear antigen for myogenic tumors of the stomach. Gastroenterol Jpn 28:193-200
31. Ruddon RW (1996) Cancer biology, 3rd edn. Oxford University Press, New York
32. Ruzicka DL, Schwartz RJ (1988) Sequential activation of α-actin genes during avian cardiogenesis: vascular smooth muscle α-actin gene transcripts mark the onset of cardiomyocyte differentiation. J Cell Biol 107:2575-2586
33. Saegusa M, Takano Y, Wakabayashi T, Okayusu I (1995) Apoptosis in gastric carcinoma and its association with proliferation and differentiation. Jpn J Cancer 86:743-748
34. Sandri M, Rizzi C, Catani C, Carraro U (1992) Small and large-scale preparative purification of myosin light and heavy chains by selective KDS precipitation of myosin subunits: yields by SDS-PAGE and quantitative orthogonal densitometry. Basic Appl Myol 2:107-114
35. Sartore S, Chiavegato A, Franch R, Faggin E, Pauletto P (1997) Myosin gene expression and cell phenotypes in vascular smooth muscle during development, in experimental models and in vascular disease. Arterioscler Thromb Vasc Biol 17:1210-1215
36. Sawtell NM, Lessard JL (1989) Cellular distribution of smooth muscle actins during mammalian embryogenesis: expression of the 2-vascular but not the γ-enteric isoform in differentiating striated myocytes. J Cell Biol 109:2929-2937
37. Schiaffino S, Reggiani C (1996) Molecular diversity of myofibrillar proteins: gene regulation and functional significance. Physiol Rev 76:371-423
38. Schiaffino S, Gorza L, Sartore S, Saggin L, Carli M (1986) Embryonic myosin heavy chain as a differentiation marker of developing human skeletal muscle and rhabdomyosarcoma. Exp Cell Res 163:211-220
39. Schmitt-Gräff A, Desmoulière A, Gabbiani G (1994) Heterogeneity of myofibroblast phenotype features: an example of fibroblastic cell plasticity. Virchows Arch 425:3-24
40. Schwartz SM, Heimark RL, Majesky MW (1990) Developmental mechanisms underlying pathology of arteries. Physiol Rev 70:1177-1209
41. Sherr CJ (1996) Cancer cell cycles. Science 274:1672-1677
42. Staunton MJ, Gaffney EF (1995) Tumor type is a determinant of susceptibility to apoptosis. Am J Clin Pathol 103:300-307
43. Truong LD, Rangdaeng S, Cagle P (1990) The diagnostic utility of desmin: a study of 584 cases and review of the literature. Am J Clin Pathol 93:305-314
44. Venuti JM, Cserjesi P (1996) Molecular embryology of skeletal myogenesis. Curr Top Dev Biol 34:169-202