Effects of lorazepam on the automatic online evaluation of sleep EEG data in healthy volunteers

Pharmacopsychiatry

Volumn 31, Issue 2, 1998, Pages 55-59

  Grozinger M ^a   Kogel P ^a   Roschke J ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE DERIVATIVE; LORAZEPAM;

ADULT; ALGORITHM; ARTICLE; ARTIFICIAL NEURAL NETWORK; AUTOMATION; CONTROLLED STUDY; DRUG WITHDRAWAL; ELECTROENCEPHALOGRAM; HUMAN; HUMAN EXPERIMENT; MALE; NONREM SLEEP; NORMAL HUMAN; ONLINE SYSTEM; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PSYCHOPHARMACOLOGY; REM SLEEP; VOLUNTEER;

EID: 0031898792     PISSN: 01763679     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-979299     Document Type: Article

References (21)

1. Borbély, A. A., P. Achermann: Ultradian dynamics of sleep after a single dose of benzodiazepine-hypnotics. Eur. J. Pharmacol. 195 (1986) 11-18
2. Borbély, A. A., P. Mattmann, M. Loepfe, I. Fellmann, M. Gerne, I. Strauch, D. Lehmann: A single dose of benzodiazepine hypnotics alters the sleep EEG in the following drug free night. Eur. J. Pharmacol. 89 (1983) 157-161
3. Borbély, A. A., P. Mattmann, M. Loepfe, I. Fellmann, D. Lehmann: Effect of benzodiazepine hypnotics on all-night sleep EEG spectra. Hum. Neurobiol. 4 (1985) 189-194
4. Grözinger, M., J. Röschke, B. Klöppel: Automatic recognition of Rapid Eye Movement (REM) sleep by artificial neural networks. J. Sleep Res. 4 (1995) 86-91
5. Grözinger, M., J. Röschke: Recognition of rapid-eye-movement (REM) sleep from single channel EEG data by artificial neural networks. A study in depressive patients with and without amitriptylin-treatment. Neuropsychobiology 33 (1996) 155-159
6. Grözinger, M., C. Wolf, T. Uhl, C. Schäffner, J. Röschke: Online detection of REM sleep based on the comprehensive evaluation of short adjacent EEG segments by Artificial Neural Networks. Progr. Neuro-Psychopharmacol. & Biol. Psychiat. 21 (1997) 951-963
7. Itil, T. M., D. M. Shapiro, W. M. Hermann, W. Schulz, V. Morgan: HZI systems for EEG parametrization and classification of psychotropic drugs. Pharmacopsychiat. 7 (1979) 4-19
8. Kales, A., E. Bixler, C. Soldatos, J. Jacoby, J. Kales: Lorazepam: Effects on sleep and withdrawal phenomena. Pharmacology 32 (1986) (3) 121-130
9. Klöppel, B.: Generalized backpropagating. In: Ewert, J.-P. and Werner, H. (Eds.): Models of Brain Function & Artificial Neuronal Nets: Proceedings of an Interdisciplinary Symposium on Neural Networks, May 28-29, University of Kassel, Germany (1990) 187-212
10. Mamelak, A., J. Quattrochi, J. Hobson: Automated staging of sleep in cats using neural networks. Electroenceph. clin. Neurophysiol. 79 (1991) 52-61
11. Rechtschaffen, A., A. Kales: A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects. Public Health Service. NIH publication 204, Washington D.C.; US Government, Printing Office (1968)
12. Robert, C., P. Karasinki, L. Stinus, A. Limoge: Adult rat vigilance state discrimination by artificial neural network using a single EEG channel. Physiol. & Behav. 59 (1996) (6) 1051-1060
13. Roberts, S., L. Tarassenko: A new method of automated sleep quantification. Med. & Biol. Eng. & Comput. 30 (1992) 509-517
14. Röschke, J., J. B. Aldenhoff: Excitability and susceptibility of the brain's electrical activity during sleep. An analysis of late components of AEP's and VEP's. International Journal of Neuroscience 56 (1991) 255-272
15. Röschke, J.: Strange attractors, chaotic behavior and informational aspects of sleep EEG data. Neuropsychobiology 25 (1992) 172-176
16. Röschke, J., P. Wagner, J. B. Aldenhoff: The influence of Lorazepam medication upon the transfer properties of the brain during sleep in man. Europ. Neuropsychopharmacology 3 (1993) 45-53
17. Roth, T., K. Hartse, P. Saab, P. Piccione, M. Kramer: The effects of Flurazepam, Lorazepam and Triazolam on sleep and memory. Psychopharmacology 70 (1980) 231-237
18. Saletu, B., J. Grünberger: Evaluation of pharmacodynamic properties of psychotropic drugs. Quantitative EEG, psychometric and blood level investigation in normals and patients. Pharmacopsychiat. 12 (1979) 45-58
19. Schaltenbrand, N., R. Lengelle, M. Toussaint, R. Luthringer, G. Carelli, A. Jacmin, E. Lainey, A. Muzet, J. P. Macher: Sleep stage scoring using the neural net model: Comparison between visual and automatic analysis in normal subjects and patients. Sleep 19 (1996) (1) 26-35
20. Vogel, G. W., F. Vogel, R. S. Mcabee, A. J. Thurmond: Improvement of depression by REM sleep deprivation: New findings and theory. Archives of General Psychiatry 37 (1980) 247-253
21. Wagner, P., J. Röschke, C. Frank: The influence of Lorazepam upon pre- and poststimulus EEG during sleep in man. Pharmacopsychiat. 30 (1997) 16-22