Side effects of chronic intrathecal baclofen on erection and ejaculation in patients with spinal cord lesions

Archives of Physical Medicine and Rehabilitation

Volumn 79, Issue 5, 1998, Pages 494-496

  Denys, Pierre ^a,b   Mane, Michèle ^a   Azouvi, Philippe ^a   Chartier Kastler, Emmanuel ^a   Thiebaut, Jean Baptiste ^a   Bussel, Bernard ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b RAYMOND POINCARÉ HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACLOFEN;

ADULT; ARTICLE; CHRONIC DISEASE; CLINICAL ARTICLE; DRUG EFFECT; EJACULATION; HUMAN; INTRATHECAL DRUG ADMINISTRATION; MALE; MALE SEXUAL DYSFUNCTION; MULTIPLE SCLEROSIS; PARAPLEGIA; PENIS ERECTION; PROSPECTIVE STUDY; QUADRIPLEGIA; SPASTICITY; SPINAL CORD INJURY;

EID: 0031898719     PISSN: 00039993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-9993(98)90061-2     Document Type: Article

References (11)

1. Penn R, Kroin JS. Intrathecal baclofen alleviates spinal cord spasticity [letter]. Lancet 1984;1:1078.
2. Penn R, Kroin JS. Continuous intrathecal baclofen for severe spasticity. Lancet 1985;2:125-7.
3. Azouvi P, Mane M, Thiebaut JB, Denys P, Rémy-Néris O, Bussel B. Intrathecal baclofen administration for control of severe spinal spasticity: functional improvement and long-term follow-up. Arch Phys Med Rehabil 1996;77:35-9.
4. Nanninga JB, Frost F, Penn RD. Effect of intrathecal baclofen on bladder and sphincter function. J Urol 1989;142:101-5.
5. Steers WD, Meythaler JM, Haworth C, Herrel D, Park TS. Effects of acute bolus and chronic intrathecal baclofen on genitourinary dysfunction due to spinal cord pathology. J Urol 1992;148:1849-55.
6. Denys P, Azouvi P, Jokic C, Mane M, Yakovleff A, Bussel B. Baclofen intrathecal. Spasticité et troubles vésicosphincteriens au cours des lésions médullaires. Ann Readapt Med Phys 1993;36:365-72.
7. Bitran D, Miller SA, McQuade DB, Leipheimer RE, Sachs BD. Inhibition of sexual reflexes by lumbosacral injection of a GABA B agonist in the male rat. Pharmacol Biochem Behav 1988;31:657-66.
8. Frankel HL, Hancok DO, Hyslop G, Melzak J, Michaelis LS, Ungar GH, et al. The value of postural reduction in the initial management of closed injuries of the spine with paraplegia and tetraplegia. Paraplegia 1969;7:179-92.
9. Granger CV, Hamilton BB. UDS report; the uniform data system for medical rehabilitation report of first admission for 1990. Am J Phys Med Rehabil 1992;72:108-13.
10. Zieglgansberger W, Howe JR, Sutor B. The neuropharmacology of baclofen. In: Müller H, Zierski J, Penn RD, editors. Local spinal therapy of spasticity. Berlin: Springer-Verlag; 1988. p. 7-50.
11. Magoul R, Oteniente B, Geffart M, Calas A. Anatomical distribution and ultrastructural organization of the GABAergic system in the rat spinal cord. An immunocytochemical study using anti GABA antibodies. Neuroscience 1987;20:1001-9.