Apomorphine-induced penile erections in Parkinson's disease

Movement Disorders

Volumn 13, Issue 3, 1998, Pages 536-539

  O'Sullivan, John D ^a   Hughes, Andrew J ^a  

^a AUSTIN HEALTH   (Australia)

Author keywords

Apomorphine; Parkinson's disease; Penile erection; Sexual function

Indexed keywords

APOMORPHINE; DOPAMINE 2 RECEPTOR;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DROWSINESS; HUMAN; IMPOTENCE; MALE; NAUSEA; PENIS ERECTION; PRIORITY JOURNAL; ROLE PLAYING; SEXUAL FUNCTION; YAWNING;

ADULT; AGED; ANTIPARKINSON AGENTS; APOMORPHINE; HUMANS; IMPOTENCE; INJECTIONS, SUBCUTANEOUS; MALE; MIDDLE AGED; PARKINSON DISEASE; PENILE ERECTION;

EID: 0031897683     PISSN: 08853185     EISSN: None     Source Type: Journal    
DOI: 10.1002/mds.870130326     Document Type: Article

References (23)

1. Stibe CMH, Lees AJ, Stern GM. Subcutaneous infusion of apomorphine in parkinsonian on-off fluctuations. Lancet 1987;i:871.
2. Stibe CMH, Kempster PA, Lees AJ, Stern GM. Subcutaneous apomorphine in parkinsonian on-off fluctuations. Lancet 1988;i: 403-406.
3. Steiger MJ, Quinn NP, Marsden CD. The clinical use of apomorphine in Parkinson's disease. J Neurol 1992;239:389-393.
4. Hughes AJ, Lees AJ, Stern GM. Apomorphine test to predict dopaminergic responsiveness in parkinsonian syndromes. Lancet 1990;336:32-34.
5. D'Costa DF, Abbott RJ, Pye IF, Millac PAH. The apomorphine test in parkinsonian syndromes. J Neurol Neurosurg Psychiatry 1991;54:870-872.
6. Gower AJ, Berendsen HHG, Princen MM, Broekamp CLE. The yawning-penile erection syndrome as a putative model for dopamine autoreceptor activity. Eur J Pharmacol 1984;103:81-89.
7. Lal S, Laryea E, Thavundayil JX, et al. Apomorphine-induced penile tumescence in impotent patients - preliminary findings. Prog Neuropsychopharmacol Biol Psychiatry 1987;11:235-242.
8. Danjou P, Alexandre L, Warot D, Lacomblez L, Puech AJ. Assessment of erectogenic properties of apomorphine and yohimbine in man. Br J Clin Pharmacol 1988;26:733-739.
9. Segraves RT, Bari M, Segraves K, Spirnak P. Effect of apomorphine on penile tumescence in men with psychogenic impotence. J Urol 1991;145:1174-1175.
10. Heaton JP, Morales A, Adams MA, Johnston B, el-Rashidy R. Recovery of erectile function by the oral administration of apomorphine. Urology 1995;45:200-206.
11. Courty E, Durif F, Zenut M, Courty P, Lavarenne J. Psychiatric and sexual disorders induced by apomorphine in Parkinson's disease. Clin Neuropharmacol 1997;20:140-147.
12. Schlatter EKE, Lal S. Treatment of alcoholism with Dent's oral apomorphine method. Quarterly Journal of Studies in Alcohol 1972;33:430-436.
13. Lal S, Ackman D, Thavundayil JX, Kiely ME, Etienne P. Effect of apomorphine, a dopamine receptor agonist, on penile tumescence in normal subjects. Prog Neuropsychopharmacol Biol Psychiatry 1984;8:695-699.
14. Goodwin FK. Psychiatric side effects of levodopa in man. JAMA 1971;218:1915-1920.
15. O'Brien CP, DiGiacomo JN, Fahn S, Schwarz GA. Mental effects of high-dosage levodopa. Arch Gen Psychiatry 1971;24:61-64.
16. Uitti RJ, Tanner CM, Rajput CH, Goetz CG, Klawans HL, Thiessen B. Hypersexuality with antiparkinsonian therapy. Clin Neuropharmacol 1989;12:375-383.
17. Lal S, Nair NPV, Iskandar HI, et al. Effect of domperidone on apomorphine-induced growth hormone secretion in normal men. J Neural Transm 1982;54:75-84.
18. Nair NPV, Lal S, Iskandar HI, Etienne P, Wood PL, Guyda H. Effect of sulpiride, an atypical neuroleptic, on apomorphine-induced growth hormone secretion. Brain Res Bull 1982;8:587-591.
19. Argiolas A, Melis MR, Mauri A, Gessa GL. Paraventricular nucleus lesion prevents yawning and penile erection induced by apomorphine and oxytocin but not by ACTH in rats. Brain Res 1987;421:349-352.
20. Paick JS, Lee SW. The neural mechanism of apomorphine-induced erection: an experimental study by comparison with electrostimulation-induced erection in the rat model. J Urol 1994;152:2125-2128.
21. Purba JS, Hofman MA, Swaab DF. Decreased number of oxytocin-immunoreactive neurons in the paraventricular nucleus of the hypothalamus in Parkinson's disease. Neurology 1994;44:84-89.
22. Brown RG, Jahanshahi M, Quinn N, Marsden CD. Sexual function in patients with Parkinson's disease and their partners. J Neurol Neurosurg Psychiatry 1990;53:480-486.
23. Singer C, Weiner WJ, Sanchez-Ramos JR. Autonomic dysfunction in men with Parkinson's disease. Eur Neurol 1992;32:134-140.