Metabolic functions of the lung

Anesthesiology Clinics of North America

Volumn 16, Issue 1, 1998, Pages 181-199

  De Wet, C ^a   Moss, J ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE DERIVATIVE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANESTHETIC AGENT; ARACHIDONIC ACID; BIOGENIC AMINE; CATECHOLAMINE; CHLORPROMAZINE; COCAINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTOXIN; FENTANYL; HALOTHANE; ICOSANOID; IMIPRAMINE; LEUKOTRIENE; LIPID; MORPHINE; OXYGEN; PEPTIDE; PETHIDINE; PROPOFOL; PROPRANOLOL; PROSTAGLANDIN; PROTEIN; STEROID; THROMBOCYTE ACTIVATING FACTOR; THROMBOXANE; UNINDEXED DRUG; VERAPAMIL; XENOBIOTIC AGENT;

ADULT RESPIRATORY DISTRESS SYNDROME; ANGIONEUROTIC EDEMA; BLOOD VESSEL TONE; DRUG DISTRIBUTION; DRUG POTENTIATION; DRUG PROTEIN BINDING; DRUG UPTAKE; HOMEOSTASIS; HUMAN; INHALATIONAL DRUG ADMINISTRATION; LIPOPHILICITY; LUNG; LUNG CIRCULATION; METABOLISM; MICHAELIS MENTEN KINETICS; MINIMUM LUNG ALVEOLUS CONCENTRATION; NONHUMAN; REVIEW;

EID: 0031897586     PISSN: 08898537     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0889-8537(05)70013-4     Document Type: Article

References (109)

1. V.A. Alabaster Inactivation of endogenous amines in the lung Y. Bakhle J. Vane Metabolic Functions of the Lung 1977 Marcel Dekker New York
2. V.A. Alabaster Y.S. Bakhle Removal of 5-hydroxytryptamine in the pulmonary circulation of rat isolated lungs Br J Pharmacol 40 1970 468 482
3. M.W. Anderson T.C. Orton R.D. Pickett Accumulation of amines in the isolated perfused rabbit lung J Pharmacol Exp Ther 189 1974 456 466
4. C.R. Baker A.D. Little C.D. Beall Kinin metabolism in the perfused ventilated rat lung. II: Influence of ventilation, perfusion, and perfusate composition variation on bradykinin metabolism in uninjured lung Circ Shock 37 1992 280 290
5. Y.S. Bakhle Pharmacokinetic and metabolic properties of lung Br J Anaesth 65 1990 79 93
6. Y.S. Bakhle J.R. Vane Pharmacokinetic function of the pulmonary circulation Physiol Rev 54 1974 1007 1045
7. B.A. Berkowitz J.H. Tarver S. Spector Norepinephrine in blood vessels: Concentration, binding, uptake and depletion J Pharmacol Exp Ther 177 1971 119 126
8. K. Bhoola C.D. Figueroa K. Worthy Bioregulation of kinins: Kallikreins, kininogens, and kininases Pharmacol Rev 44 1992 1 80
9. J.C. Boileau C. Crexells P. Biron Free pulmonary passage of dopamine Rev Can Biol 31 1972 69 72
10. G. Bonner S. Preis U. Schunk Hemodynamic effects of bradykinin on systemic and pulmonary circulation in healthy and hypertensive humans J Cardiovasc Pharmacol 15 suppl 6 1990 S46 S56
11. M.A. Boogaerts O. Yamada H.S. Jacob Enhancement of granulocyte-endothelial cell adherence and granulocyte-induced cytotoxicity by platelet release products Proc Natl Acad Sci USA 79 1982 7019 7023
12. R.G. Carlini A. Gupta H. Liapis Endothelin-1 release by erythropoietin involves calcium signaling in endothelial cells J Cardiovasc Pharmacol 26 1995 889 892
13. M. Chinkers D.L. Garbers Signal transduction by guanylyl cyclases Annu Rev Biochem 60 1991 553 575
14. D.R. Cook B.W. Brandom Enflurane, halothane, and isoflurane inhibit removal of 5-hydroxytryptamine from the pulmonary circulation Anesth Analg 61 1982 671 675
15. D.W. Cushman H.S. Cheung E.F. Sabo Development of specific inhibitors of angiotensin I converting enzyme (kininase II) Fed Proc 38 1979 2778 2782
16. C.A. Dawson D.L. Roerig J.H. Linehan Evaluation of endothelial injury in the human lung Clin Chest Med 10 1989 13 24
17. R.H. Demling C. Wong R. Fox Relationship of increased lung serotonin levels to endotoxin-induced pulmonary hypertension in sheep: Effect of a serotonin antagonist Am Rev Respir Dis 132 1985 1257 1261
18. G. De Nucci R. Thomas P. D'Orleans-Juste Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor Proc Natl Acad Sci USA 85 1988 9797 9800
19. K.J. Dobuler J.D. Catravas C.N. Gillis Early detection of oxygen-induced lung injury in conscious rabbits: Reduced in vivo activity of angiotensin converting enzyme and removal of 5-hydroxytryptamine Am Rev Respir Dis 126 1982 534 539
20. C.A. Duncan Lung metabolism of xenobiotic compounds Clin Chest Med 10 1989 49 58
21. E.G. Erdos A.R. Johnson N.T. Boyden Hydrolysis of enkephalin by cultured human endothelial cells and by purified peptidyl depeptidase Biochem Pharmacol 27 1978 843 848
22. S.F. Evans S. Medbak C.J. Hinds Plasma levels and biochemical characterization of circulating met-enkephalin in canine endotoxic shock Life Sci 34 1984 1481 1486
23. B.L. Fanburg Prostaglandins and the lung Am Rev Respir Dis 108 1973 482 489
24. J.R. Fineman S.J. Soifer M.A. Heymann Regulation of pulmonary vascular tone in the perinatal period Annu Rev Physiol 57 1995 115 134
25. A.P. Fishman G.G. Pietra Handling of bioactive materials by the lung (first of two parts) N Engl J Med 291 1974 884 890
26. A.P. Fishman G.G. Pietra Handling of bioactive materials by the lung (second of two parts) N Engl J Med 291 1974 953 959
27. R.J. Flower Prostaglandin metabolism in the lung Y. Bakhle J. Vane Metabolic Functions of the Lung 1977 Marcel Dekker New York
28. J.H. Gaddum C.O. Hebb A. Silver 5-hydroxytryptamine: Pharmacological action and destruction in perfused lungs Q J Exp Physiol 38 1953 252 262
29. 14C-propranolol by the lung Thorax 34 1979 810 813
30. M.N. Gillespie J.W. Krechniak P.A. Crooks Pulmonary metabolism of exogenous enkephalins in isolated perfused rat lungs J Pharmacol Exp Ther 232 1985 675 681
31. C.N. Gillis Extraneuronal transport of noradrenaline in the lung D. Paton The Mechanism of Neuronal and Extraneuronal Transport of Catecholamines 1976 Raven Press New York
32. C.N. Gillis Metabolism of vasoactive hormones by lung Anesthesiology 39 1973 626 632
33. C.N. Gillis Pharmacological aspects of metabolic processes in the pulmonary microcirculation Annu Rev Pharmacol Toxicol 26 1986 183 200
34. C.N. Gillis J.D. Catravas Altered removal of vasoactive substances in the injured lung: Detection of lung microvascular injury Ann N Y Acad Sci 384 1982 458 474
35. C.N. Gillis L.H. Cronau N.M. Greene Removal of 5-hydroxytryptamine and norepinephrine from the pulmonary vascular space of man: Influence of cardiopulmonary bypass and pulmonary arterial pressure on these processes Surgery 76 1974 608 616
36. C.N. Gillis L.H. Cronau S. Mandel Indicator dilution measurement of 5-hydroxytryptamine clearance by human lung J Appl Physiol 46 1979 1178 1183
37. C.N. Gillis B.R. Pitt The fate of circulating amines within the pulmonary circulation Annu Rev Physiol 44 1982 269 281
38. C.N. Gillis J.A. Roth Pulmonary disposition of circulating vasoactive hormones Biochem Pharmacol 25 1976 2547 2553
39. R. Ginn J.R. Vane Disappearance of catecholamines from the circulation Nature 291 1968 740 742
40. M.S. Goligorsky H. Tsukahara H. Magazine Termination of endothelin signaling: Role of nitric oxide J Cell Physiol 158 1994 485 494
41. K. Gonmori K.S. Rao H.M. Mehendale Pulmonary synthesis of 5-hydroxytryptamine in isolated perfused rabbit and rat lung preparations Exp Lung Res 11 1986 295 305
42. J. Gutkowska M. Nemer M.J. Sole Lung is an important source of atrial natriuretic factor in experimental cardiomyopathy J Clin Invest 83 1989 1500 1504
43. C. Hardy C. Robinson R.A. Lewis Airway and cardiovascular responses to inhaled prostacyclin in normal and asthmatic subjects Am Rev Respir Dis 131 1985 18 21
44. T. Higenbottam D. Wheeldon F. Wells Long-term treatment of primary pulmonary hypertension with continuous intravenous epoprostenol (prostacyclin) Lancet 1 1984 1046 1047
45. R.E. Howell J.H. Hansen-Flaschen E.B. Wheeldon Pulmonary angiotensin-converting enzyme activity in the oxygen-toxic sheep Am Rev Respir Dis 138 1988 160 166
46. J.C. Hudson W.H. Wurm T.F. O'Donnell Jr Ibuprofen pretreatment inhibits prostacyclin release during abdominal exploration in aortic surgery Anesthesiology 72 1990 443 449
47. Y. Huet C. Brun-Buisson F. Lemaire Cardiopulmonary effects of ketanserin infusion in human pulmonary embolism Am Rev Respir Dis 135 1987 114 117
48. C.C. Hug Pharmacokinetics and dynamics of narcotic analgesics C. Prys-Roberts C.C. Hug Pharmacokinetics of Anesthesia 1984 Blackwell London
49. W.V. Huval M.A. Mathieson L.I. Stemp Therapeutic benefits of 5-hydroxytryptamine inhibition following pulmonary embolism Ann Surg 197 1983 220 225
50. L.J. Ignarro G.N. Buga K.S. Wood Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide Proc Natl Acad Sci USA 84 1987 9265 9269
51. T. Inagami M. Naruse R. Hoover Endothelium as an endocrine organ Annu Rev Physiol 57 1995 171 189
52. Y. Iwasawa C.N. Gillis Pharmacological analysis of norepinephrine and 5-hydroxytryptamine removal from the pulmonary circulation: Differentiation of uptake sites for each amine J Pharmacol Exp Ther 188 1974 386 393
53. Y. Iwasawa C.N. Gillis G. Aghajanian Hypothermic inhibition of 5-hydroxytryptamine and norepinephrine uptake by lung: Cellular location of amines after uptake J Pharmacol Exp Ther 186 1973 498 507
54. A. Jackowski A. Crockard G. Burnstock 5-Hydroxytryptamine demonstrated immuno histochemically in rat cerebrovascular nerves largely represents 5-hydroxytryptamine into sympathetic nerve fibers Neuroscience 29 1989 453 462
55. H.S. Jacob C.F. Moldow P.J. Flynn Therapeutic ramifications of the interaction of complement, granulocytes, and platelets in the production of acute lung injury Ann NY Acad Sci 384 1982 489 495
56. L. Jorfeldt D.H. Lewis J.B. Löfström Lung uptake of lidocaine in man as influenced by anaesthesia, mepivacaine infusion or lung insufficiency Acta Anaesthesiol Scand 27 1983 5 9
57. 14C-imipramine in isolated perfused rat lungs J Pharmacol Exp Ther 183 1972 182 187
58. A.F. Junod The lung as a chemical filter Ergeb Inn Med Kinderheild 36 1974 1 18
59. A.F. Junod Mechanism of drug accumulation by the lung A. Junod R. Deltalles Lung Metabolism 1975 Academic Press New York
60. 14C-5–hydroxytryptamine in isolated perfused rat lungs J Pharmacol Exp Ther 183 1972 341 355
61. A.F. Junod Uptake, release and metabolism of drugs in the lungs Pharmacol Ther 2 1976 511 521
62. G.S. Kobinia P.J. LaRaia M.B. Peterson Cardiac prostacyclin kinetics during cardiopulmonary bypass J Thorac Cardiovasc Surg 88 1984 965 971
63. 2α metabolism in sheep: An in vivo model Prostaglandins Leukot Essent Fatty Acids 38 1989 195 202
64. D.M. Kornhauser R.E. Vestal D.G. Shand Uptake of propranolol by the lung and its displacement by other drugs: Involvement of the alveolar macrophage Pharmacology 20 1980 275 283
65. J.A. Lang G. Yang J.A. Kern Endogenous human renin expression and promoter activity in CALU-6, a pulmonary carcinoma cell line Hypertension 25[part 2] 1995 704 710
66. P. Leuenberger Clinical importance of non-respiratory functions of the lung (French) Schweiz Med Wochenschr 113 1983 1006 1010
67. E.R. Levin Endothelins N Engl J Med 333 1995 356 363
68. D. Manwaring K. Mullane Disappearance of enkephalins in the isolated perfused rat lung Life Sci 35 1984 1787 1794
69. I. Matot C.F. Neely R.Y. Katz Pulmonary uptake of propofol in cats: Effects of fentanyl and halothane Anesthesiology 78 1993 1157 1165
70. J.V. Mombouli P.M. Vanhoutte Heterogeneity of endothelium-dependent vasodilator effects of angiotensin-converting enzyme inhibitors: Role of bradykinin generation during ACE inhibition J Cardiovasc Pharmacol 20 suppl 9 1992 S74 S82
71. J.V. Mombouli P.M. Vanhoutte Kinins and endothelial control of vascular smooth muscle Annu Rev Pharmacol Toxicol 35 1995 679 705
72. D.R. Morel F. Dargent M. Bachmann Pulmonary extraction of serotonin and propranolol in patients with adult respiratory distress syndrome Am Rev Respir Dis 132 1985 479 484
73. T. Morita H.M. Mehendale Effects of chlorphentermine and phentermine on the pulmonary disposition of 5-hydroxytryptamine in the rat in vivo Am Rev Respir Dis 127 1983 747 750
74. H. Naito C.N. Gillis Effects of halothane and nitrous oxide on removal of norepinephrine from the pulmonary circulation Anesthesiology 39 1973 575 580
75. P. Needleman E.H. Blaine J.E. Greenwald The biochemical pharmacology of atrial peptides [review] Annu Rev Pharmacol Toxicol 29 1989 23 54
76. K.K. Ng J.R. Vane Conversion of angiotensin I to angiotensin II Nature 216 1967 762 766
77. 3Hnorepinephrine by isolated perfused rat lungs Circ Res 35 1974 670 680
78. M.B. Peterson V. Machaj P.C. Block Thromboxane release during percutaneous transluminal coronary angioplasty Am Heart J 111 1996 1 6
79. P.J. Piper J.R. Vane J.H. Wyllie Inactivation of prostaglandins by the lungs Nature 225 1970 600 604
80. B.R. Pitt C.N. Gillis G.L. Hammond Depression of pulmonary metabolic function by cardiopulmonary bypass procedures increases levels of circulating norepinephrine Ann Thorac Surg 38 1984 508 513
81. B.R. Pitt G. Lister Interpretation of metabolic function of the lung: Influence of perfusion, kinetics, and injury Clin Chest Med 10 1989 1 12
82. M.M. Rappaport A.A. Greene I.H. Page Serum vaso-constrictor (serotonin) J Biol Chem 176 1948 1243 1251
83. D.L. Roerig S.B. Ahlf C.A. Dawson First pass uptake in the human lung of drugs used during anesthesia Adv Pharmacol 31 1994 531 549
84. D.L. Roerig R.R. Dahl C.A. Dawson Effect of plasma protein binding on the uptake of methadone and diazepam in the isolated perfused rat lung Drug Metab Dispos 12 1984 536 542
85. D.L. Roerig K.J. Kotrly S.B. Ahlf Effect of propranolol on the first pass uptake of fentanyl in the human and rat lung Anesthesiology 71 1989 62 68
86. D.L. Roerig K.J. Kotrly C.A. Dawson First-pass uptake of verapamil, diazepam, and thiopental in the human lung Anesth Analg 69 1989 461 466
87. D.L. Roerig K.J. Kotrly E.F. Vucins First pass uptake of fentanyl, meperidine, and morphine in the human lung Anesthesiology 67 1987 466 472
88. M.F. Roizen R.W. Horrigan B.M. Frazer Anesthetic doses blocking adrenergic (stress) and cardiovascular responses to incision—MAC BAR Anesthesiology 54 1981 390 398
89. 14C) 5-hydroxytryptamine J Pharmacol Exp Ther 240 1987 410 414
90. S.I. Said Metabolic functions of the pulmonary circulation Circ Res 50 1982 325 333
91. M. Simionescu Metabolic activities of the lung Ciba Found Symp 78 1980 143
92. R.A. Skidgel Bradykinin-degrading enzymes: Structure, function and potential roles in cardiovascular pharmacology J Cardiovasc Pharmacol 20 suppl 9 1992 S4 S9
93. M.J. Sole M. Drobac L. Schwartz The extraction of circulating catecholamines by the lungs in normal man and in patients with pulmonary hypertension Circulation 60 1979 160 163
94. E.H. Starling E.B. Verney The secretion of urine as studied on the isolated kidney Proc R Soc Lond B Biol Sci 97 1925 321 363
95. K. Taeger E. Weninger F. Schmelzer Pulmonary kinetics of fentanyl and alfentanil in surgical patients Br J Anaesth 61 1988 425 434
96. D.P. Thomas J.R. Vane 5-Hydroxytryptamine in the circulation of the dog Nature 216 1967 335 338
97. J.R. Vane The alteration or removal of vasoactive hormones by the pulmonary circulation D. Tedeschi R. Tedeschi The Importance of Fundamental Principles in Drug Evaluation 1968 Raven Press New York
98. J.R. Vane The release and fate of vaso-active hormones in the circulation Br J Pharmacol 35 1969 209 242
99. P.M. Vanhoutte C.M. Boulanger M.J. Vidal Endothelium-derived mediators and the renin-angiotensin system J. Robertson M. Nicholls The Renin-Angiotenin System 1993 Gower Medical London
100. D.L. Vesely S. Chiou M.A. Douglass Atrial natriuretic peptides negatively and positively modulate circulating endothelin in humans Metabolism 45 1996 315 319
101. N.F. Voelkel S.W. Chang T.J. McDonnel Role of membrane lipids in the control of normal vascular tone Am Rev Respir Dis 136 1987 214 217
102. N.F. Voelkel K.R. Stenmark J.Y. Westcott Lung eicosanoid metabolism Clin Chest Med 10 1989 95 105
103. N. Von Lutterotti D.F. Catanzaro J.E. Sealey Renin is not synthesized by cardiac and extrarenal vascular tissues. A review of experimental evidence Circulation 89 1994 458 470
104. 1 for severe idiopathic pulmonary artery hypertension (letter) Lancet 1 1980 1083
105. H.P. Wiedemann M.A. Matthay C.N. Gillis Pulmonary endothelial cell injury and altered lung metabolic function. Early detection of the adult respiratory distress syndrome and possible functional significance Clin Chest Med 11 1990 723 736
106. A.G. Wilson R.D. Pickett T.E. Eling Studies on the persistence of basic amines in the rabbit lung Drug Metab Dispos 7 1979 420 424
107. J.R. Wright S. Hawgood Pulmonary surfactant metabolism Clin Chest Med 10 1989 83 93
108. D. Xu N. Emoto A. Giaid ECE-1: A membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1 Cell 78 1994 473 485
109. M. Yanagisawa H. Kurihara S. Kimura A novel potent vasoconstrictor peptide produced by vascular endothelial cells Nature 332 1988 411 415