Neuropeptides and Langerhans cells

Experimental Dermatology

Volumn 7, Issue 2-3, 1998, Pages 73-80

  Lambert, R W ^a   Granstein, R D ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

Calcitonin gene related peptide; Langerhans cells; Neuropeptides; Substance P; Vasoactive intestinal peptide

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; NEUROPEPTIDE; NEUROPEPTIDE Y; NEUROTENSIN; SOMATOSTATIN; SUBSTANCE P; VASOACTIVE INTESTINAL POLYPEPTIDE;

HORMONAL REGULATION; HORMONE ACTION; HUMAN; IMMUNOCOMPETENT CELL; LANGERHANS CELL; NEUROGENIC INFLAMMATION; NONHUMAN; REVIEW;

EID: 0031897563     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0625.1998.tb00306.x     Document Type: Review

References (84)

1. Cohen S, Williamson G M. Stress and infectious disease in humans. Psychol Bull 1991: 109: 5-24.
2. Peterson P K, Chau C C, Molitor T et al. Stress and pathogenesis of infectious disease. Rev Infect Dis 1991: 13: 710-720.
3. Feiten D L, Feiten S Y, Carlson S L, Olschowka J A, Linvat S. Noradrenergic and peptidergic innervation of lymphoid tissue. J Immunol 1985: 135: 755s-765s.
4. Zaidi M, Moonga B S, Bevis P J, Bascal Z A, Breimer L H. The calcitonin gene peptides: Biology and clinical relevance. Crit Rev Clin Lab Sci 1990: 28: 109-174.
5. Abello J, Kaiserlian D, Cuber J C, Revillard J P, Chayvialle J A. Characterization of calcitonin gene related peptide receptors and adenylate cyclase response in the murine macrophaee cell line P388D1. Neuropeptides 1991: 19: 43-49.
6. Wang F, Millet I, Bottomly K, Vignery A. Calcitonin gene-related peptide inhibits interleukin-2 production by murine T lymphocytes. J Biol Chem 1992: 267: 21052-21057.
7. Umeda Y, Takamiya M, Yoshizaki H, Arisawa M. Inhibition of mitogen-stimulated T-lymphocyte proliferation by calcitonin gene-related peptide. Biochem Biophys Res Commun 1988: 154: 227-235.
8. Foster C A, Mandak B, Kromer E, Rot A. Calcitonin gene-related peptide is chemotactic for human T lymphocytes. Ann NY Acad Sci 1992: 657: 397-404.
9. Torii H, Hosoi J, Beissert S et al. Regulation of cytokine expression in macrophages and the Langerhans cell-like line XS52 by calcitonin gene-related peptide. J Leukoc Biol 1997: 61: 216-223.
10. Nong Y H, Titus R G, Ribeiro J M, Remold H G. Peptides encoded by the calcitonin gene inhibit macrophage function. J Immunol 1989: 143: 459.
11. Umeda Y. Inhibition of immune responses by calcitonin gene-related peptide. Ann NY Acad Sci 1992: 657: 552-554.
12. Smith C H, Barker J N, Morris R W, MacDonald D M, Lee T H. Neuropeptides induce rapid expression of endothelial cell adhesion molecules and elicit granulocytic infiltration in human skin. J Immunol 1993: 151: 3274-3282.
13. Said S I. Vasoactive intestinal peptides and related peptides: Preface. Ann NY Acad Sci 1988: 527: xiii.
14. O'Dorisio M S, O'Dorisio T M, Wood C L et al. Characterization of vasoactive intestinal peptide receptors in nervous and immune systems. Ann NY Acad Sci 1988: 527: 257-265.
15. Goetzl E J, Xia M, Ingram D A et al. Neuropeptide signaling of lymphocytes in immunological responses. Int Arch Allergy Immunol 1995: 107: 202-204.
16. Wilder R L. Neuroendocrine-immune system interactions and autoimmunity. Annu Rev Immunol 1995: 13: 307-338.
17. Stanisz A M, Scicchitano R, Bienenstoch J. The role of vasoactive intestinal peptide and other neuropeptides in the regulation of the immune response in vitro and in vivo. Ann NY Acad Sci 1988: 527: 47885.
18. Piotrowski W, Foreman J C. On the actions of substance P, somatostatin and vasoactive intestinal polypeptide on rat peritoneal mast cells and in human skin. Naunyn Schmiedebergs Arch Pharmacol 1985: 331: 364-368.
19. Pernow B. Role of tachykinins in neurogenic inflammation. J Immunol 1985: 135: 812s-815s.
20. Lotti T, Hautmann G, Panconesi E. Neuropeptides in skin. J Am Acad Dermatol 1995: 33: 482-496.
21. Chancellor-Freeland C, Zhu G F, Kage R, Beller D I, Leeman S E, Black P H. Substance P and stress-induce changes in macrophages. Ann NY Acad Sci 1995: 771: 472-484.
22. Härtung H P, Wolters K, Toya K V Substance P: binding properties and studies on cellular responses in guinea pig macrophages. J Immunol 1986: 136: 3856-3863.
23. Payan D G, Brewster D R, Missirian-Bastin A, Goetzl E J. Substance P recognition by a subset of human T-lymphocytes. J Clin Invest 1984: 74: 1532-1539.
24. Lotz M, Vaughan J H, Carson D A. Effects of neuropeptides on production of inflammatory cytokines by human monocytes. Science 1989: 241: 1218-1221.
25. Malis W L, Lavker R M, Murphy G F. Substance P induces thé expression of an endothelial-leukocyte adhesion molecule by microvascular endothelium. J Invest Dermatol 1990: 94: 492-495.
26. Vincent J P. Neurotensin receptors: Binding properties, transduction pathways, and structure. Cell Mol Neurobiol 1995: 15: 501-512.
27. Lemaire I. Neurotensin enhances IL-1 production by activated alveolar macrophages. J Immunol 1988: 140: 2983-2988.
28. Wintzen M, Gilchrest B A. Proopiomelanocortin, its derived peptides, and the skin. J Invest Dermatol 1996: 106: 3-10.
29. Lipton J M, Catania A. Anti-inflammatory actions of the neuroimmunomodulator a-MSH. Immunol Today 1997: 18: 140-145.
30. Luger T A, Schauer E, Trautinger F et al. Production of immunosuppressing melanotropins by human keratinocytes. Ann NY Acad Sci 1993: 680: 508-510.
31. Rheins L A, Cotleur A L, Kleier R S et al. Alpha-meianocyte stimulating hormone modulates contact hypersensitivity responsiveness in C57/BL6 mice. J Invest Dermatol 1989: 93: 511-517.
32. Grabbe S, Bhardwaj R S, Mahnke K et al. Alpha-melanocyte-stimulating hormone induces hapten-specific tolerance in mice. J Immunol 1996: 156: 473-478.
33. Pincelli C, Fantini F, Giannetti A. Neuropeptides and skin inflammation. Dermatology 1993: 187: 153-158.
34. Brain S D, Williams T J, Morris H R, Maclntyre I. Calcitonin gene-related peptide is a potent vasodilator. Nature 1985: 313: 54-56.
35. Gamse R, Posch M, Saria A, Jancso G. Several mediators appear to interact in neurogenic inflammation. Acta Physiologica Hungarica 1987: 69: 343-354.
36. Dux M, Jancso G, Sann H, Pierau F K. Inhibition of the neurogenic inflammatory response by lidocaine in rat skin. Inflamm Res 1996: 45: 10-13.
37. Lowman M A, Benyon R C, Church M K. Characterization of neuropeptide-induced histamine release from human dispersed skin mast cells. Br J Pharmacol 1988: 95: 121-130.
38. Piotrowski W, Foreman J C. Some effects of calcitonin gene-related peptide in human skin and on histamine release. Br J Dermatol 1986: 114: 37-46.
39. Kowalski M L, Sliwinska-Kowalska M, Kaliner M A. Neurogenic inflammation, vascular permeability, and mast cells. II. Additional evidence indicating that mast cells are not involved in neurogenic inflammation. J Immunol 1990: 145: 1214-1221.
40. Kowalski M L, Kaliner M A. Neurogenic inflammation, vascular permeability, and mast cells. J Immunol 1988: 140: 3905-3911.
41. Jorizzo J L, Coutts A A, Eady RAJ, Greaves M W. Vascular responses of human skin to injection of substance P and mechanism of action. Eur J Pharmacol 1983: 87: 67-76.
42. Veronesi B, Sailstad D M, Doerfler D L, Seigrade M. Neuropeptide modulation of chemically induced skin irritation. Toxicol Appl Pharmacol 1995: 135: 258-267.
43. Meggs W J. Neurogenic inflammation and sensitivity to environmental chemicals. Environ Health Perspect 1993: 101: 234-238.
44. Eedy D J, Shaw C, Johnston C F, Buchanan K D. The regional distribution of neuropeptides in human skin as assessed by radioimmunoassay and high-performance liquid chromatography. Clin Exp Dermatol 1994: 19: 463-472.
45. Moller K, Zhang Y Z, Hakanson R et al. Pituitary adenylate cyclase activating peptide is a sensory neuropeptide: immunocytochemical and immunochemical evidence. Neurosci 1993: 57: 725-732.
46. Baraniuk J N. Neuropeptides in the Skin. In: Bos J D, ed. Skin immune system. New York: CRC Press LLC, 1997: 311-323.
47. Girolomoni G, Tigelaar R E. Peptidergic neurons and vasoactive intestinal peptide modulate experimental delayed type hypersensitivity reactions. Ann NY Acad Sci 1992: 650: 9-12.
48. Haegerstrand A, Jonzon B, Dalsgaard C J, Nilsson J. Vasoactive intestinal polypeptide stimulates cell proliferation and adenyl cyclase activity of cultured human keratino-cytes. Proc Natl Acad Sci 1989: 86: 5993-5996.
49. Kemeny L, von Restorff B, Michel G, Ruzicka T. Specific binding and lack of growth-promoting activity of substance P in cultured human keratinocytes. J Invest Dermatol 1994: 103: 605-606.
50. Farooqui J Z, Medrano E E, Abdel-Malek Z, Nordlund J. The expression of proopiomelanocortin and various POMC-derived peptides in mouse and human skin. Ann NY Acad Sci 1993: 680: 508-510.
51. Thody A J, Hunt G, Donatien P D, Todd C. Human melanocytes express functional melanocyte-stimulating hormone receptors. Ann NY Acad Sci 1993: 680: 381-390.
52. Johansson O. A detailed account of NPY-immunoreactive nerves and cells of the human skin: comparison with VIP-substance P- and PHI-containing structures. Acta Physiol Scand 1986: 128: 147-157.
53. Bernstein J E, Parish L C, Rapaport M, Rosenbaum M M, Roenigk H H. Effects of topically applied capsaicin on moderate and severe psoriasis vulgaris. J Am Acad Dermatol 1986: 15: 504-507.
54. Mozzanica N, Cattaneo A, Vignati G, Finzi A. Plasma neuropeptide levels in psoriasis. Acta Dermatol Venereol 1994: 186s: 67-68.
55. Al'Abadie M S K, Senior H J, Bleehen S S, Gawkrodger D J. Neuropeptides and general neuronal marker in psoriasis - an immunohistochemical study. Clin Exp Dermatol 1995: 20: 384-389.
56. Al'Abadie M S K, Senior H J, Bleehen S S, Gawkrodger D J. Neuropeptide and neuronal marker studies in vitiligo. Br J Dermatol 1994: 131: 160-165.
57. Liu P Y, Bondesson L, Lontz W, Johansson O. The occurrence of cutaneous nerve endings and neuropeptides in vitilieo vulearis: a case control study. Arch Dermatol Res 1996: 288: 670-675.
58. Ek L, Theodorsson E. Tachykinins and calcitonin gene-related peptides in oxazalone-induced allergic contact dermatitis in mice. J Invest Dermatol 1990: 94: 761-763.
59. Goebeler M, Henseleit U, Roth J, Sorg C. Substance P and calcitonin gene-related peptide modulate leukocyte infiltration to mouse skin during allergic contact dermatitis. Arch Dermatol Res 1994: 286: 341-346.
60. Ostlere L S, Cowen T, Rustin M H. Neuropeptides in the skin of patients with atopic dermatitis. Gin Exp Dermatol 1995: 20: 46267.
61. Dalsgaard C J, Jernbeck J, Stains W et al. Calcitonin generelated peptide-like immunoreactivity in nerve fibers in the human skin. Histochemistry 1989: 91: 35-38.
62. Hosoi J, Murphy G F, Egan C L et al. Regulation of Langerhans cell function by nerves containing calcitonin generelated peptide. Nature 1993: 363: 159-163.
63. Wallengren J, Ekman R, Sundler F. Occurrence and distribution of NP in human skin. Acta Dermatol Venereol (Stockh) 1987: 67: 185-192.
64. Fox F E, Kubin M, Cassin M et al. Calcitonin gene-related peptide inhibits proliferation and antigen presentation by human peripheral blood mononuclear cells: effects on B7, interleukin 10, and interleukin 12. J Invest Dermatol 1997: 108: 43-48.
65. Stingl G, Wolff-Schreiner E C, Pichler W J et al. Epidermal Langerhans cells bear Fc and C3 receptors. Nature 1977: 268: 245-246.
66. Rowden G. Immuno-electron microscopic studies of surface receptors and antigens of human Langerhans cells. Br J Dermatol 1977: 97: 593-608.
67. Tamaki K, Stingl G, Gullino M, Sachs D H, Katz S I. la antigens in mouse skin are predominantly expressed on Langerhans cells. J Immunol 1979: 123: 784-787.
68. Concha M, Figueroa C D, Caorsi I. Ultrastructural characteristics of the contact zones between Langerhans cells and lymphocytes. J Path 1988: 156: 29-36.
69. Grabbe S, Bruvers S, Granstein R D. Effects of immunomodulatory cytokines on the presentation of tumor-associated antigens by epidermal Langerhans cells. J Invest Dermatol 1992: 99: 66S-68S.
70. Hogan A D, Burks A W. Epidermal Langerhans' cells and their function in the skin immune system. Ann Allergy Asthma Immunol 1995: 75: 5-10.
71. Teunissen M B M. Dynamic nature and function of epidermal Langerhans cells in v/vo and in ritro: a review, with emphasis on human Langerhans cells. Histochem J 1992: 24: 697-716.
72. Black P H. Immune system-central nervous system interactions: effect and immunomodulatory consequences of immune system mediators on the brain. Antimicrob Agents Chemother 1994: 38: 7-12.
73. Gaudillere A, Misery L, Souchier C, Claudy A, Schmitt D. Intimate associations between PGP9.5-positive nerve fibers and Langerhans cells. Br J Dermatol 1996: 135: 343-344.
74. Hsieh S T, Choi S, Lin W M, Chang Y C, McArthur J C, Griffin J W. Epidermal denervation and its effects on keratinocytes and Langerhans cells. J Neurocytol 1996: 25: 513-524.
75. Staniek V, Misery L, Dezutter-Dambuyant C, Claudy A, Schmitt D. Expression of neuropeptides on human epidermal Langerhans cells. Dendritic Cells in Fundamental and Clinical Immunology 1995: 2: 147-150.
76. Pincelli C, Fantini F, Massimi P, Giannetti A. Neuropeptide Y-like immunoreactivity in Langerhans cells from patients with atopic dermatitis. Int J Neuroscience 1990: 51: 219-220.
77. Misery L, Gaudillere A, Claudy A, Schmitt D. Expression of somatostatin on Langerhans cells. Dendritic Cells in Fundamental and Clinical Immunology 1995: 2: 109-110.
78. Asahina A, Hosoi J, Beissert S, Stratigos A, Granstein R D. Inhibition of the induction of delayed-type and contact hypersensitivity by calcitonin gene-related peptide. J Immunol 1995: 154: 3056-3061.
79. Asahina A, Moro O, Hosoi J, Lerner E A, Xu S, Takashima A, Granstein R D. Specific induction of cAMP in Langerhans cells by calcitonin gene-related peptide: relevance to functional effects. Proc Natl Acad Sci 1995: 92: 8323-8327.
80. Torii H, Yan Z, Hosoi J, Granstein R. Expression of neurotrophic factors and neuropeptide receptors by epidermal Langerhans cells and the Langerhans cell-like line XS52: further support for a functional relationship between Langerhans cells and epidermal nerves. J Invest Dermatol (in press).
81. Staniek V, Misery L, Peguet-Navarro J et al. Binding and in vitro modulation of human epidermal cell functions by substance P. Arch Dermatol Res 1997: 289: 285-291.
82. Hopkins S J, Rothwell N J. Cytokines and the nervous system I: expression and recognition. Trends Neurosci 1995: 18: 83-88.
83. Owens T, Renno T, Taupin V, Krakowski M. Inflammatory cytokines in the brain: does the CNS shape immune responses? Immunol Today 1994: 15: 566-571.
84. Otten U, Scully J L, Ehrhard P B, Gadient R A. Neurotrophins: signals between the nervous and immune systems. Prog Brain Res 1994: 103: 293-305.