Stromal factors support the expansion of the whole hemopoietic spectrum from bone marrow CD34+DR- cells and of some hemopoietic subsets from CD34+ and CD34+DR+ cells

Leukemia

Volumn 12, Issue 5, 1998, Pages 735-745

  Herman, Ph ^a   Ferrant, A ^a   De Bruyere M ^a   Straetmans, N ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Cytokines; Ex vivo expansion of human bone marrow cells; Stroma conditioned medium

Indexed keywords

CD34 ANTIGEN; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 11; INTERLEUKIN 3; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; STEM CELL FACTOR;

ARTICLE; BONE MARROW CELL; BURST FORMING UNIT E; COLONY FORMING UNIT GM; HUMAN; HUMAN CELL; MEGAKARYOCYTE; PRIORITY JOURNAL;

EID: 0031897346     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2400924     Document Type: Article

References (15)

1. Simmons PJ, Haylock DN. Use of hematopoietic growth factors for in vitro expansion of precursor cell populations. Curr Opin Hematol 1995; 2: 189-195.
2. + cells into the myeloid lineage. Blood 1992; 80: 1405-1412.
3. Srour EF, Brandt JE, Bridell RA, Grisby S, Leemhuis T, Huffman R. Long-term generation and expansion of human primitive hematopoietic cells in vitro. Blood 1993; 81: 661-669.
4. + cells. J Hematother 1993; 2: 221-224.
5. + cells. Blood 1993; 82: 3600-3609.
6. Brandt I, Bridell A, Srour EF, Leemhuis TB, Hoffman R. Role of c-kit ligand in the expansion of human hematopoietic progenitors. Blood 1992; 79: 634-641.
7. + selected human peripheral blood progenitor cells. Blood 1994; 84: 2898-2903.
8. Petzer AL, Hogge DE, Lansdorp PM, Reid DS, Eaves CJ. Self-renewal of primitive human hematopoietic cells (long-term-culture-initiating cells) in vitro and their expansion in defined medium. Proc Natl Acad Sci USA 1996; 93: 1470-1474.
9. Muench MO, Firpo MT, Moore MAS. Bone marrow transplantation with interleukin-1 plus c-kit ligand ex vivo expanded bone marrow accelerates hematopoietic reconstitution in mice without the loss of stem cell ineage and proliferative potential. Blood 1993; 81: 3463-3473.
10. Serano F, Varas F, Bernard A, Bueren JA. Accelerated and long-term hematopoietic engraftment in mice transplanted with ex vivo expanded bone marrow. Bone Marrow Transplant 1994; 14: 855-862.
11. Peters SO, Kittler ELW, Ramshaw HS, Quesenberry PJ. Murine marrow cells expanded in culture with IL-3, IL-6, IL-11, and SCF acquire an engraftment defect in normal hosts. Exp Hematol 1995; 23: 461-469.
12. Peters SO, Kittler ELW, Ramshaw HS, Quesenberry PJ. Ex vivo expansion of murine marrow cells with interleukin-3 (IL-3), IL-6, IL-11, and stem cell factor leads to impaired engraftment in irradiated hosts. Blood 1996; 87: 30-37.
13. Yonemura Y, Ku H, Hirayama F, Souza LM, Ogawa M. Interleukin 3 or interleukin 1 abrogates the reconstituting ability of hematopoi- etic stem cells. Proc Natl Acad Sci USA 1996; 93:4040-4044.
14. Brugger W, Heimfeld S, Berenson RJ, Mertelsman R, Kanz L. Reconstitution of hematopoiesis after high dose chemotherapy by autologous progenitor cells generated ex vivo. New Engl J Med 1995; 333: 283-287.
15. + cells in autologous stem cell transplantation for breast cancer. Blood 1996; 87: 1687-1691.