Irreversible binding of a carbostyril-based agonist and antagonist to the β-adrenoceptor in DDT1 MF-2 cells and rat aorta

British Journal of Pharmacology

Volumn 124, Issue 1, 1998, Pages 165-175

  Deyrup, Malgorzata D ^a   Greco, Phillip G ^a   Otero, Deborah H ^a   Dennis, Donn M ^a   Gelband, Craig H ^a   Baker, Stephen P ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

adrenoceptor; ( ) Isoprenaline; 5(2 (((1' (4' Isothiocyanatophenylamino) thiocarbonyl)amino) 2 methylpropyl)amino 2 hydroxypropoxy) 3,4 dihydrocarbostyril (DCITC); 8 Hydroxy 5(2 (((1' (4' isothiocyanatophenylamino)thiocarbonyl)amino) 2 methylprop 2 yl)amino 1 hydroxyethyl) carbostyril (HCITC); Chemoreactive ligands; Cyclic AMP; DDT1; Isolated aorta; MF 2 cells; Propranolol

Indexed keywords

5 (2 (((1' (4' ISOTHIOCYANATOPHENYLAMINO)THIOCARBONYL)AMINO) 2 METHYLPROP 2 YL)AMINO 1 HYDROXYETHYL)CARBOSTYRIL; 5 (2 (((1' (4' ISOTHIOCYANATOPHENYLAMINO)THIOCARBONYL)AMINO) 2 METHYLPROPYL)AMINO 2 HYDROXYPROPOXY) 3,4 DIHYDROCARBOSTYRIL; ACETYLCHOLINE; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CARBOSTYRIL DERIVATIVE; CYANOIODOPINDOLOL; CYCLIC AMP; FORSKOLIN; ISOPRENALINE; PROPRANOLOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; AORTA; AORTA CONSTRICTION; ARTERY DILATATION; ARTICLE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DOSE RESPONSE; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; MALE; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY;

ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; AORTA; CELL LINE; HYDROXYQUINOLINES; ISOPROTERENOL; MALE; QUINOLONES; RATS;

EID: 0031897217     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701801     Document Type: Article

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