Effects of Cadmium On Liver Function in Diabetic Rats

Toxicology and Industrial Health

Volumn 14, Issue 3, 1998, Pages 473-477

  Rana, Suresh V S ^a   Rastogi, Nidhi ^a  

^a CH CHARAN SINGH UNIVERSITY   (India)

Author keywords

serum glutamyl oxalacetic transaminase; serum glutamyl pyruvic transaminase; SGOT; SGPT

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CADMIUM; CYTOCHROME P450; GAMMA GLUTAMYLTRANSFERASE;

ALLOXAN DIABETES MELLITUS; ANIMAL MODEL; ARTICLE; DIABETES MELLITUS; ENZYME ACTIVITY; HEAVY METAL POISONING; LIVER FUNCTION TEST; LIVER TOXICITY; MALE; NONHUMAN; RAT; TOXICOKINETICS;

ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CADMIUM; DIABETES MELLITUS, EXPERIMENTAL; DIET; GAMMA-GLUTAMYLTRANSFERASE; LIVER; MALE; RATS; RATS, INBRED STRAINS;

ANIMALIA;

EID: 0031896620     PISSN: 07482337     EISSN: None     Source Type: Journal    
DOI: 10.1177/074823379801400306     Document Type: Article

References (19)

1. Chawalit, K., Sretarugsa, P., and Thithapandha, A. (1982). “Comparative effect of diabetogenic agents on hepatic drug metabolism.” Drug Metab. Dispos. 10:84-86.
2. Cook, D.E., Jackson, J.D., Past, M.K., Long, C.M., and Bullock, L.P. (1984). “Drug metabolism in spontaneously diabetic guinea pigs.” Experiment 40:840-841.
3. Hanasone, G.K., Cote. M.G., and Plaa, G.L. (1975). “Potentiation of carbontetrachloride induced hepato-toxicity in alloxan or streptozotocin diabetic rats.” J. Pharmacol. Exp. Therap. 192:592-604.
4. Junko, S. and Etsuka, F. (1984). “Changes in alkaline phasphatase activity in rats administered cadmium chloride Eisei.” Kagasku 30:309-312.
5. Longhurst, P.A., Lacagnin, L.B., Stoats, D.E., and Colby H.D. (1986). “Changes in hepatic drug metabolism in alloxan diabetic male rabbits.” Biochem. Pharmacol. 35:1768-1771.
6. Morton, R.K. (1955). Method in Enzymology (S.P. Colowick and N.O. Kaplon, eds.) Academic Press, New York, NY. pp. 1–25.
7. Orlouski, M. and Meister, A. (1973). “γ-glutamyl cyclotransferase distribution, isozymic forms and specificity.” J. Biol. Chem. 248:2836-2844.
8. Past, M.R. and Cook, D.E. (1982). “Effect of diabetes on rat liver cytochrome P450. Evidence for a unique diabetes dependent rat liver cytochrome P450.” Biochem. Pharmacol. 31:3329-3334.
9. Price, V.F. and Jollow, D.J. (1982). “Increased resistance of diabetic rats to acetaminophen induced hepatotoxicity.” J. Pharmacol. Exp. Therap. 220:504-513.
10. Price, V.F. and Jollow, D.J. (1983). “Mechanism of Ketone induced protection from acetaminophen hepatotoxicity in the rat.” Drug. Metab. Dispos. 11:451-457.
11. Rana, S.V.S., Agarwal, V.P., and Bhardwaj, N.G. (1983). “Some observations on liver function in rats after cadmium poisoning.” Sci Cult. 49:331-330.
12. Rana, S.V.S., Agarwal, V.P., and Bhardwaj, N.G. (1984). “Cadmium and zinc induced nuclear changes in the liver and kidney of rats.” Int. J. Tiss. Reac. 3:57-64.
13. Rana, S.V.S., Rastogi, S., and Sharma, S. (1993). “Lipid-peroxidation induced by cadmium in the liver and kidney of diabetic rats.” In: Trace and Toxic Elements in Nutrition and Health. (M. Abdulla, S.B. Vohra, and M. Athar, eds.). Wiley Easten Limited, New Delhi, India. pp. 223–226.
14. Rana, S.V.S. and Rastogi, N. (1997). “Antioxidative enzymes in the liver and kidney of diabettic rats and their implicattions in cadmium toxicity,” Redox Report (In Press).
15. Reitman, S. and Frankel, S. (1957). “A colorimeter method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminase.” Amer. J. Clin. Pathol. 28:56-63.
16. Robinson, D.S. (1961). “Alloxan-diabetes and insulin effects on amino acid incorporation activity of rat liver microsomes.” Proc. Soc. Exp. Biol. Med. 106:115-118.
17. Saunders, G.K. (1987). “The effects of excess renal copper on kidney function in diabetic rats.” Res. Commun. Chem. Path Pharmacology 52:45-49.
18. Sjegers, C.P. and Watkins, J.B., III (1991). “Biliary excretion of drugs and other chemicals. “ In: Progress in Pharmacology and Clinical Pharmacology. Fischer Verlag, Stuttgart, Gerrmany 8(4).
19. Watkins, J.B., III and Saunders, RA (1991). “The effects of diabetes on hepatobiliary function.” In: Biliary Excretion of Drugs and Other Chemicals, (C.P Siegers and J.B. Watkins III, eds.). Progress in Pharmacology and Clinical Pharmacology. Fischer Verlag, Stuttgart, Germany 8:475-496.