Ifosfamide in the treatment of advanced or recurrent squamous cell carcinoma of the head and neck: A phase II hoosier oncology group trial

American Journal of Clinical Oncology: Cancer Clinical Trials

Volumn 21, Issue 2, 1998, Pages 195-197

  Sandler, Alan ^a,b   Saxman, S ^b   Bandealy, M ^b   Heilman, D ^b   Monaco, F ^a   McClean, J ^c   Arquette, M ^d  

^a Hoosier Oncology Group   (United States)

^b INDIANA UNIVERSITY   (United States)

^c Galesburg Clinic   (United States)

^d WASHINGTON UNIVERSITY   (United States)

Author keywords

Head and neck carcinoma; Ifosfamide; Squamous cell carcinoma

Indexed keywords

IFOSFAMIDE; MESNA;

ADULT; AGED; ANEMIA; ARTICLE; CANCER SURVIVAL; CARDIOTOXICITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; GRANULOCYTOPENIA; HEAD AND NECK CANCER; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LUNG TOXICITY; MAJOR CLINICAL STUDY; MALE; NEPHROTOXICITY; SQUAMOUS CELL CARCINOMA; THROMBOCYTOPENIA; TREATMENT OUTCOME; VOMITING;

EID: 0031896533     PISSN: 02773732     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000421-199804000-00021     Document Type: Article

References (12)

1. Parker SL, Tong T, Bolden S, et al. Cancer statistics. CA Cancer J Clin 1997;47:5-27.
2. Vokes EE, Weichselbaum RR, Lippman SM, et al. Head and neck cancer. N Engl J Med 1993;328:184-94.
3. Vokes EE. Head and neck cancer. In: Perry MC, ed. Chemotherapy source book. Baltimore: Williams & Wilkins, 1992:918-31.
4. Jacobs C, Lyman G, Velez-Garcia E, et al. A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck. J Clin Oncol 1992;10:257-63.
5. Forastiere AA, Metch B, Schuller DE, et al. Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: a Southwest Oncology Group study. J Clin Oncol 1992;10:1245-51.
6. Zalupski M, Baker LH. Ifosfamide. J Natl Cancer Inst 1988;80:556-66.
7. Buesa JM, Fernandez R, Esteban E, et al. Phase II trial of Ifosfamide in recurrent and metastatic head and neck cancer. Ann Oncol 1991;2:151-2.
8. Martin M, Duaz-Rubio E, Gonzalez Larriba JL, et al. Ifosfamide in advanced epidermoid head and neck cancer. Cancer Chemother Pharmacol 1993;31:340-2.
9. Kish JA, Tapazoglou E, Ensley J, et al. Activity of ifosfamide in recurrent head and neck cancer patients [Abstract]. Proceedings of the American Association of Cancer Research 1990;31:190.
10. Cervellino JC, Araujo CE, Pirisi C, et al. Ifosfamide and mesna for the treatment of advanced squamous cell head and neck cancer. A Getlac Study. Oncology 1991;48:89-92.
11. Pai VR, Parikh DN, Mazumdar AT, et al. Phase II study of high-dose ifosfamide as a single agent and in combination with cisplatin in the treatment of squamous cell carcinoma of head and neck. Oncology 1993;50:86-91.
12. Huber MH, Lippman SM, Benner SE, et al. A phase II study of ifosfamide in recurrent squamous cell carcinoma of the head and neck. Am J Clin Oncol 1996;19:379-82.