Indinavir crystalluria: Identification of patients at increased risk of developing nephrotoxicity

Archives of Pathology and Laboratory Medicine

Volumn 122, Issue 3, 1998, Pages 256-259

  Trainor, Lance D ^a   Steinberg, James P ^b   Austin, Glenn W ^c   Solomon, Harvey M ^d  

^a EMORY UNIVERSITY HOSPITAL   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Louis C Herring and Company   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; COTRIMOXAZOLE; DAPSONE; INDINAVIR; LAMIVUDINE; PROTEINASE INHIBITOR; STAVUDINE; ZIDOVUDINE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CRYSTALLURIA; HIGH RISK PATIENT; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; NEPHROLITHIASIS; NEPHROTOXICITY; URINALYSIS; URINE PH; URINE SEDIMENT;

CRYSTALLIZATION; HIV INFECTIONS; HIV PROTEASE INHIBITORS; HUMANS; HYDROGEN-ION CONCENTRATION; INDINAVIR; KIDNEY CALCULI; MALE; RISK FACTORS; URINE;

EID: 0031896249     PISSN: 00039985     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Crixivan® (indinavir sulfate) package insert. West Point, Pa: Merck & Co Inc.
2. Deeks SG, Smith M, Holodniy M. HIV-1 protease inhibitors. JAMA. 1997; 277:145-153.
3. Balani SK, Ariso BH, Mathai L. Metabolites of L-735,524, a potent HIV-1 protease inhibitor, in human urine. Drug Metab Dispos. 1995;23:266-270.
4. Lin JH, Chen I-W, Vastag KJ, et al. pH-dependent oral absorption of L-735,524, a potent HIV protease inhibitor, in rats and dogs. Drug Metab Dispos. 1995;23:730-735.
5. Daudon M, Estepa L, Viard JP, et al. Urinary stones in HIV-1-positive patients treated with indinavir. Lancet. 1997;349:1294-1295.
6. Brau N, Leaf HL, Wieczorek RL, et al. Severe hepatitis in three AIDS patients treated with indinavir. Lancet. 1997;349:924-925.
7. Tashima KT, Horowitz JD, Rosen S. Indinavir nephropathy. N Engl J Med. 1997;336:1138-1140.
8. Sulfamethoxazole and trimethoprim tablet package insert. Pine Brook, NJ: Medirex Inc.
9. Phelps P, Steele AD, McCarty DJ. Compensated polarized light microscopy. JAMA. 1968;203:166-170.
10. Daudon M, Réveillard RJ. Cristalluries medicamenteuses: mythes et réalités. Ann Biol Clin. 1986;44:25-34.
11. Kopp JB, Miller KD, Mican JAM, et al. Crystalluria and urinary tract abnormalities associated with indinavir. Ann Intern Med. 1997;127:119-125.