Pharmacokinetics and inflammatory fluid penetration of clinafloxacin

Antimicrobial Agents and Chemotherapy

Volumn 42, Issue 2, 1998, Pages 428-430

  Wise, R ^a   Jones, S ^a   Das, I ^a   Andrews, J M ^a  

^a CITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CLINAFLOXACIN;

ADULT; ARTICLE; BLISTER; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG PENETRATION; DRUG URINE LEVEL; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; TISSUE WATER;

ADULT; ANTI-INFECTIVE AGENTS; CANTHARIDIN; FLUOROQUINOLONES; HUMANS; INFLAMMATION; MALE; QUINOLONES;

EID: 0031894929     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Bennett, J. V., J. L. Brodie, E. J. Benner, and W. M. M. Kirby. 1966. Simplified, accurate method for antibiotic assay of clinical specimens. Appl. Microbiol. 14:170-177.
2. Bron, N. J., M. B. Dorr, T. S. Mant, C. Webb, and A. B. Vassos. 1996. The tolerance and pharmacokinetics of clinafloxacin (CI-960) in healthy subjects. J. Antimicrob. Chemother. 38:1023-1029.
3. Child, J., F. Boswell, N. Brenwald, J. M. Andrews, and R. Wise. 1995. In vitro activity of CP 99,219, a new naphthyridone antimicrobial: a comparison with other fluoroquinolone agents. J. Antimicrob. Chemother. 35:869-876.
4. Johnson, J. H., M. A. Cooper, J. M. Andrews, and R. Wise. 1992. Pharmacokinetics and inflammatory fluid penetration of sparfloxacin. Antimicrob. Agents Chemother. 36:2444-2446.
5. Norrby, S. R., and M. Jonsson. 1988. Comparative in vitro activity of PD 127,391, a new fluorinated 4-quinolone derivative. Antimicrob. Agents Chemother. 32:1278-1281.
6. Stone, J. W., J. M. Andrews, J. P. Ashby, D. Griggs, and R. Wise. 1988. Pharmacokinetics and tissue penetration of orally administered lomefloxacin. Antimicrob. Agents Chemother. 32:1508-1510.
7. Wise, R., A. P. Gillette, B. Cadge, S. R. Durham, and S. Baker. 1980. The influence of protein binding upon tissue levels of six beta lactam antibiotics. J. Infect. Dis. 142:77-82.
8. Wise, R., J. P. Ashby, and J. M. Andrews. 1988. In vitro activity of PD 127,391, an enhanced-spectrum quinolone. Antimicrob. Agents Chemother. 32:1251-1256.
9. Wise, R., D. Mortiboy, J. Child, and J. M. Andrews. 1996. Pharmacokinetics and penetration into inflammatory fluid of trovafloxacin (CP-99,219). Antimicrob. Agents Chemother. 40:47-49.