Drug marker absorption in relation to pellet size, gastric motility and viscous meals in humans

Pharmaceutical Research

Volumn 15, Issue 2, 1998, Pages 233-238

  Rhie, Julie K ^a,b   Hayashi, Yayoi ^a,c   Welage, Lynda S ^a,d   Frens, Jeremy ^a   Wald, Randy J ^e   Barnett, Jeffrey L ^d   Amidon, Gregory E ^e   Putcha, Lakshmi ^f   Amidon, Gordon L ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c NAGOYA CITY UNIVERSITY   (Japan)

^d UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^e PFIZER INC   (United States)

^f NASA JOHNSON SPACE CENTER   (United States)

Author keywords

Acetaminophen; Caffeine; Enteric coated; Gastric emptying; Gastric motility; Oral absorption; Viscous meal

Indexed keywords

CAFFEINE; PARACETAMOL;

ADULT; ARTICLE; CALORIC INTAKE; CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET RESTRICTION; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG PELLET; ENTERIC COATED TABLET; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MEAL; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; PRIORITY JOURNAL; STOMACH ANTRUM; STOMACH EMPTYING; STOMACH MOTILITY; VISCOSITY;

NASA CENTER JSC; NASA DISCIPLINE REGULATORY PHYSIOLOGY; NON-NASA CENTER;

ACETAMINOPHEN; ADULT; AREA UNDER CURVE; CAFFEINE; FEMALE; FOOD-DRUG INTERACTIONS; GASTRIC EMPTYING; HUMANS; MALE; VISCOSITY;

EID: 0031894013     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011962501270     Document Type: Article

References (22)

1. J. H. Meyer, J. Elashoff, V. Porter-Fink, J. Dressman, and G. L. Amidon. Gastroenterology. 94:1315-1325 (1988).
2. R. Khosla, L. C. Feely, and S. S. Davis. Int J Pharm. 53:107-117 (1989).
3. J. H. Meyer, Y. Gu, J. Elashoff, T. Reedy, J. Dressman, and G. L. Amidon. Am J Phys. 250:G161-G164 (1986).
4. S. S. Davis, A. F. Stockwell, M. J. Taylor, J. G. Hardy, D. R. Whalley, C. G. Wilson, H. Bechgaard, and F. N. Christensen. Pharm Res. 3:208-213 (1986).
5. P. J. Sirois, G. L. Amidon, J. H. Meyer, J. Doty, and J. B. Dressman. Am J Phys. 258:G65-G72 (1990).
6. N. Najib, A. R. Mansour, and G. L. Amidon. Chem Eng J. 37:B39-B46 (1988).
7. L. A. Houghton, N. W. Read, R. Heddle, M. Horowitz, P. J. Collins, B. Chatterton, and J. Dent. Gastroenterology. 94:1285-1291 (1988).
8. P. R. McHugh and J. Auton Nerv Sys. 9:221-231 (1983).
9. R. J. Wald. Personal Communication. Pharmacia & Upjohn. Kalamazoo, MI 1995.
10. The Dow Chemical Co. Methocel Cellulose Ethers Technical Handbook. Dow Chemical, Midland, MI, 1988.
11. H. N. Alkaysi, M. S. Salem, and Y. M. El-Sayed. J. Clin Pharm Ther. 13:109-115 (1988).
12. S. E. O'Connell and F. J. Zurzola. J Pharm Sci. 71:1291-1294 (1982).
13. D. Bratchel and E. Richter. Z. Gastroenterologie. 26:245-251 (1988).
14. T. E. Chvasta and A. R. Cooke. Gastroenterology. 61:838-843 (1971).
15. J. A. Clements, R. C. Heading, W. S. Nimmo, and L. F. Prescott. J. Clin. Pharmacol. Ther. 24:420-431 (1978).
16. J. Blanchard and S. J. A. Sawers. Eur J Clin Pharmacol. 24:93-98 (1983).
17. W. S. Nimmo, R. C. Heading, J. Wilson, P. Tothill, and L. F. Prescott. 2:509-513 (1975).
18. N. Kaniwa, N. Aoyagi, H. Ogata, and A. Ejima. J Pharmacobio Dynamics. 4:563-570 (1988).
19. C. Reppas, J. H. Meyer, P. J. Sirois, and J. B. Dressman. Gastroenterology. 100:1217-1223 (1991).
20. A. Medhus, O. Sandstad, J. Bredesen, and E. Husebye. Neurogastroenterol Mot. 7:1-8 (1995).
21. Sirois P. J. Size and density discrimination of nondigestible solids during emptying from the canine stomach: a hydrodynamic correlation. Doctoral Disseration, Ann Arbor, 1989.
22. P. Mojaverian, P. H. Vlasses, P. E. Kellner, and M. L. Rocci. Pharm. Res. 5:639-644 (1988).