Rat group I metabotropic glutamate receptors inhibit neuronal Ca2+ channels via multiple signal transduction pathways in HEK 293 cells

Journal of Neurophysiology

Volumn 79, Issue 1, 1998, Pages 379-391

  McCool, Brian A ^a,d   Pin, Jean Phillipe ^b   Harpold, Michael M ^c   Brust, Paul F ^c   Stauderman, Kenneth A ^c   Lovinger, David M ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INSERM   (France)

^c SIBIA Corp   (United States)

^d TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; GUANINE NUCLEOTIDE BINDING PROTEIN; METABOTROPIC RECEPTOR; N ETHYLMALEIMIDE; PERTUSSIS TOXIN;

ANIMAL CELL; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ELECTRIC POTENTIAL; HUMAN; HUMAN CELL; NERVE CELL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0031893815     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1998.79.1.379     Document Type: Article

References (46)

1. ARAMORI, I. AND NAKANISHI, S. Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluR1, in transfected CHO cells. Neuron 8: 757-765, 1992.
2. ASANO, T. AND OGASAWARA, N. Uncoupling of γ-aminobutyric acid B receptors from GTP-binding proteins by N-ethylmaleimide: effect of N-ethylmaleimide on purified GTP-binding proteins. Mol. Pharmacol. 29: 244-249, 1986.
3. BASHIR, Z. I., BORTOLOTTO, Z. A., DAVIES, C. H., BERRETIA, N., IRVING, A. J., SEAL, A. J., HENLEY, J. M., JANE, D. E., WATKINS, J. C., AND COLLINGRIDGE, G. L. Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors. Nature 363: 347-350, 1993.
4. BEECH, D. J., BERNHEIM, L., AND HILLE, B. Pertussis toxin and voltage dependence distinguish multiple pathways modulating calcium channels of rat sympathetic neurons. Neuron 8: 97-106, 1992.
5. BRUST, P. F., SIMERSON, S., MCCUE, A. F., DEAL, C. R., SCHOONMAKER, S., WILLIAMS, M. E., VELICELEBI, G., JOHNSON, E. C., HARPOLD, M. M., AND ELLIS, S. B. Human neuronal voltage-dependent calcium channels: studies on subunit structure and role in channel assembly. Neuropharmacol 32: 1089-1102, 1993.
6. αo in rat sympathetic neurons. J. Physiol. (Lond.) 477: 415-422, 1994.
7. 2+ channels involves multiple receptor subtypes in cortical neurons. J. Neurosci. 16: 36-45, 1996.
8. CHOI, S., MCCOOL, B. A., IKEDA, S., AND LOVINGER, D. M. Mechanism of inhibition of calcium channels by multiple subtypes for mGluRs in isolated cortical neurons. Soc. Neurosci. Abstr. 21: 340, 1995.
9. CONN, P. J. AND PIN, J.-P. Pharmacology and functions of metabotropic glutamate receptors. Annu. Rev. Pharmacol. Toxicol. 37: 205-237, 1997.
10. CULLEN, G. P., HUSTON, E., AND DOLPHIN, A. C. Cycloheximide abolishes pertussis toxin-induced increase in glutamate release from cerebellar granule neurones. Neurosci. Lett. 166: 17-22, 1994.
11. DESAI, M. AND CONN, P. J. Excitatory effects of ACPD receptor activation in the hippocampus are mediated by direct effects on pyramidal cells and blockade of synaptic inhibition. J. Neurophysiol. 66: 40-52, 1991.
12. FLOR, P. J., GOMEZA, J., TONES, M. A., KUHN, R., PIN, J.-P., AND KNOPFEL, T. The C-terminal domain of the mGluR1 metabotropic glutamate receptor affects sensitivity to agonists. J. Neurochem. 67: 58-63, 1996.
13. GEREAU, R. W. AND CONN, P. J. Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmissions in hippocampal area CA1. J. Neurosci. 15: 6879-6889, 1995.
14. GLAUM, S. R., SLATER, N. T., ROSSI, D. J., AND MILLER, R. J. Role of metabotropic glutamate (ACPD) receptors at the Parallel Fiber-Purkinje cell synapse. J. Neurophysiol. 68: 1453-1462, 1992.
15. + current by metabotropic and muscarinic receptors in rat CA3 cells: mediation by G-proteins. J. Physiol. (Lond.) 474: 27-33, 1994.
16. HAMIL, O. P., MARTY, A., NEHER, E., SAKMANN, B., AND SIGWORTH, F. J. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch. 391: 85-100, 1981.
17. HAY, M. AND KUNZE, D. L. Glutamate metabotropic receptor inhibition of voltage-gated calcium currents in visceral sensory neurons. J. Neurophysiol. 72: 421-430, 1994.
18. HELL, J. W., APPLEYARD, S. M., YOKOYAMA, C. T., WARNER, C., AND CATTERALL, W. A. Differential phosphorylation of two size forms of the N-type calcium channel alpha 1 subunit which have different COOH termini. J. Biol. Chem. 269: 7390-7396, 1994.
19. HOSHINO, S.-I., KIKKAWA, S., TAKAHASHI, K., ITOH, H., KAZIRO, Y., KAWASAKI, H., SUZUKI, K., KATADA, T., AND UI, M. Identification of sites for alkylation by N-ethylmaleimide and pertussis toxin-catalyzed ADP-ribosylation on GTP-binding proteins. FEBS Lett. 276: 227-231, 1990.
20. IKEDA, S. R. Double-pulse calcium channel current facilitation in adult rat sympathetic neurones. J. Physiol. (Lond.) 439: 181-214, 1991.
21. IKEDA, S. R., LOVINGER, D. M., MCCOOL, B. A., AND LEWIS, D. L. Heterologous expression of metabotropic glutamate receptors in adult rat sympa-thetic neurons: subtype-specific coupling to ion channels. Neuron 14: 1029-1038, 1995.
22. JOLY, C., GOMEZA, J., BRABET, I., CURRY, K., BOCKAERT, J., AND PIN, J.-P. Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1. J. Neurosci. 15: 3970-3981, 1995.
23. KASAI, H. Tonic inhibition and rebound facilitation of a neuronal calcium channel by a GTP-binding protein. Proc. Natl. Acad. Sci. USA 88: 8855-8859, 1991.
24. KINGSTON, A. E., BURNETT, J. P., MAYNE, N. G., AND LODGE, D. Pharmacological analysis of 4-corboxyphenylglycine derivatives: comparison of effects on mGluR1α and mGluR5a subtypes. Neuropharmacology 34: 887-894, 1995.
25. KRAMER, R. H., KACZMAREK, L. K., AND LEVITAN, E. S. Neuropeptide inhibition of voltage-gated calcium channels mediated by mobilization of intracellular calcium. Neuron 6: 557-563, 1991.
26. LOVINGER, D. M., MERRITT, A., AND REYES, D. Involvement of N-and non-N-type calcium channels in synaptic transmission at corticostriatal synapses. Neuroscience 62: 31-40, 1994.
27. MCBAIN, C. J., DICHIARA, T. J., AND KAUER, J. A. Activation of metabotropic glutamate receptors differentially affects two classes of hippocampal interneurons and potentiates excitatory synaptic transmission. J. Neurosci. 14: 4433-4445, 1994.
28. MCCOOL, B. A., PIN, J.-P., BRUST, P. F., HARPOLD, M. M., AND LOVINGER, D. M. Functional coupling of rat group II metabotropic glutamate receptors (mGluR 2&3) to a ω-conotoxin GVI-sensitive calcium channel in HEK 293 cells. Mol. Pharmacol. 50: 912-922, 1996.
29. MILANI, D., CANDEO, P., FAVARON, M., BLACKSTONE, C. D., AND MANEV, H. A subpopulation of cerebellar granule neurons in culture express a functional mGluR1 metabotropic glutamate receptor: effect of depolarizing growing conditions. Receptors Channels 1: 243-250, 1993.
30. OCLESE, R., QIN, N., SCHNEIDER, T., NEELY, A., WEI, X., STEFANI, E., AND BIRNBAUMER, L. The amino terminus of a calcium channel β subunit sets rates of channel inactivation independently of the subunit's effect on activation. Neuron 13: 1433-1438, 1994.
31. PICKERING, D. S., THOMSEN, C., SUZDAK, P. D., FLETCHER, E. J., ROBITAILLE, R., SALTER, M. W., MACDONALD, J. F., HUANG, X., AND HAMPSON, D. R. A comparison of two alternatively spliced forms of a metabotropic glutamate receptor coupled to phosphoinositide turnover. J. Neurochem. 61: 85-92, 1993.
32. PIN, J.-P., WAEBER, C., PREZEAU, L., BOCKAERT, J., AND HEINEMANN, S. F. Alternative splicing generates metabotropic glutamate receptors inducing different patterns of calcium release in Xenopus oocytes. Proc. Natl. Acad. Sci. USA 89: 10331-10335, 1992.
33. SAHARA, Y. AND WESTBROOK, G. L. Modulation of calcium channels by a metabotropic glutamate receptor involves fast and slow kinetic components in cultured hippocampal neurons. J. Neurosci. 13: 3041-3050, 1993.
34. SCHMIDT, M., FASSELT, B., RUMENAPP, U., BIENEK, C., WIELAND, T., AND MALINOFF, P. B. Mechanisms of up-regulation of D2L dopamine receptors by agonists and antagonists in transfected HEK-293 cells. J. Pharmacol. Exp. Ther. 271: 1574-1582, 1994.
35. SCHOEPP, D., BOCKAERT, J., AND SLADECZEK, F. Pharmacological and functional characteristics of metabotropic excitatory amino acid receptors. Trends Pharmacol. Sci. 11: 508-515, 1990.
36. SCHOEPP, D. D. AND JOHNSON, B. G. Inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in the rat hippocampus by 2-amino-3-phosphonoproprionate. J. Neurochem. 53: 1865-1870, 1989.
37. 2+ channels by PTX-sensitive G-proteins is blocked by N-ethylmaleimide in rat sympathetic neurons. J. Neurosci. 14: 7109-7116, 1994a.
38. SHAPIRO, M., WOLLMUTH, L. P., AND HILLE, B. Angiotensin II inhibits calcium and M current in rat sympathetic neurons via G proteins. Neuron 12: 1319-1329, 1994b.
39. SUZDAK, P. D., SHEARDOWN, M. J., AND HONOR, T. Characterization of the metabotropic glutamate receptor in mouse cerebellar granule cells: lack of effect of 2,3-dihydroxy-6-nitro-7-sulphamoylben-zo(F)-quinoxaline (NBQX). Eur. J. Pharmacol. 245: 215-220, 1993.
40. SWARTZ, K. AND BEAN, B. P. Inhibition of calcium channels in rat CA3 pyramidal neurons by a metabotropic glutamate receptor. J. Neurosci. 12: 4358-4371, 1992.
41. TAKAHASHI, T. AND MOMIYAMA, A. Different calcium channels mediate central synaptic transmission. Nature 366: 156-158, 1993.
42. TANABE, Y., MASU, M., ISHII, T., SHIGEMOTO, R., AND NAKANISHI, S. A family of metabotropic glutamate receptors. Neuron 8: 169-179, 1992.
43. TOTH, P. T., SHEKTER, L. R., HUI MA, G., PHILIPSON, L. H., AND MILLER, R. L. Selective G-protein regulation of neuronal calcium channels. J. Neurosci. 16: 4617-4624, 1996.
44. WERZ, M. A., ELMSLIE, K. S., AND JONES, S. W. Phosphorylation enhances inactivation of N-type calcium channel current in bullfrog sympathetic neurons. Pflügers Arch. 424: 538-545, 1993.
45. ZHENG, F. AND GALLAGHER, J. P. Pharmacologically distinct, pertussis toxin-resistant inward currents evoked by metabotropic glutamate receptor (mGluR) agonists in dorsolateral septal nucleus (DLSN) neurons. J. Neurosci. 15: 504-510, 1995.
46. 2+ channels of sympathetic neurons via a pertussis toxin-insensitive but cholera toxin-sensitive pathway. Neuron 13: 657-669, 1994.