Effects of fractionated irradiation on the cytoskeleton and basal lamina in parotid glands: An immunohistochemical study

Acta Oncologica

Volumn 37, Issue 1, 1998, Pages 33-40

  Gustafsson, Hans ^a   Aalto, Yan ^a   Franzén, Lars ^a   Thornell, Lars Eric ^a   Henriksson, Roger ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN; DESMIN; FIBRONECTIN; GLIAL FIBRILLARY ACIDIC PROTEIN; LAMININ; MEMBRANE PROTEIN; VIMENTIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; CONTROLLED STUDY; CYTOSKELETON; ELECTRON MICROSCOPY; FEMALE; IMMUNOFLUORESCENCE; NONHUMAN; PAROTID GLAND TUMOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION DOSE FRACTIONATION; RAT;

ACTINS; ANIMALS; BASEMENT MEMBRANE; CYTOSKELETON; DESMIN; FEMALE; FIBRONECTINS; IMMUNOHISTOCHEMISTRY; LAMININ; MICROSCOPY, ELECTRON; PAROTID GLAND; RATS; RATS, SPRAGUE-DAWLEY; VIMENTIN;

EID: 0031893664     PISSN: 0284186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/028418698423159     Document Type: Article

References (30)

1. Henriksson R, Fröid Ö, Gustafsson H, Yi-Qing C. Franzen L. Bjermer L. Increase in mast cells and hyaluronic acid correlates to radiation induced damage and loss of serous acinar cells in salivary glands: the parotid and submundibular glands differ in their radiosensitivity. Br J Cancer 1994; 69: 320-6.
2. Akita S. Nagayama M, Kaneda T, Oka T, Ohishi N, Yagi K. Effects of 7-ray irradiation on Superoxide dismutase activity and lipid peroxidase level in mouse salivary glands. J Appl Biochem 1984; 6: 64-9.
3. Franzén L, Funegård U, Sundström S. Gustafsson H, Danielsson Henriksson R. Fractionated irradiation and early changes in salivary glands. Different effects on potassium efflux, exocytic amylase release and gland morphology. Lab Invest 1991; 64: 279-83.
4. Franzén L, Gustafsson H, Sundström S, Karlsson M, Littbrand B, Henriksson R. Fractionated irradiation and late changes in rat parotid gland: effects on the number of acinar cells, potassium efflux, and amylase secretion. Int J Radiat Biol 1993; 64: 93-101.
5. Pratt NE, Sodicoff M, Liss J, Davis M, Sinesi M. Radioprotection of the rat parotid gland by WR-2721: morphology at 60 days post-irradation. Int J Radiat Oncol Biol Phys 1980; 6: 431-5.
6. Savage NW, Kruger BJ, Adkins KF. The effects of fractionated megavoltage X-irradiation on the rat submandibular glands: an assessment by electron microscopy. Austr Dent J 1985; 30: 188-93.
7. Abok K, Brunk U, Jung B, Eriksson J. Morphologic and histochemical studies on the differing radiosensitivity of ductular and acinar cells of the rat submandibular gland. Virchows Arch B (Cell Pathol) 1984; 45: 443-60.
8. Norberg L, Lundquist P-G. An ultrastructural study of salivary gland radiosensitivity after alpha-adrenergic stimulation. ANL (Tokyo) 1988; 15: 1-17.
9. Pratt NE, Sodicoff M. Ultrastructural injury following X-irradiation of rat parotid gland acinar cells. Archs Oral Biol 1972; 17: 1177-86.
10. Cherry CP, Glücksman A. Injury and repair following irradiation of salivary glands in male rats. Br J Radiol 1959; 32: 596-608.
11. Gabbiani G. Kappanci Y, Barrazone P. Franke WW. Immunohistochemical identification of intermediate-sized filaments in human neoplastic cells. A diagnostic aid for the surgical pathologist. Am J Pathol 1981; 104: 206-16.
12. Moll R. Cytokeratins in the histological diagnosis of malignant tumours. Int J Biol Markers 1994; 9: 63-9.
13. McLean WH, Lane EB. Intermediate filaments in disease. Curr Opin Cell Biol 1995; 7: 118-25.
14. 14C-leucine administration. Stralentherapie 1979; 155: 508-11.
15. Virtanen I, Kallajoki M. Närvänen O, et al. Peritubular myoid cells of human rat testis are smooth muscle cells that contain desmin-type intermediate filaments. Anat Rec 1986; 215: 10 -20.
16. Vartio T, Laitinen L. Närvänen O, et al. Differential expression of the ED sequence form of cellular fibronectin in embryonic and adult human tissue. J Cell Sci 1987; 88: 419-30.
17. Gustafsson H, Kjörell U, Eriksson A, et al. Distribution of intermediate filament proteins in developing and adult salivary glands in man. Anat Embryol 1988; 178: 243-51.
18. Gustafsson H, Franzén L, Henriksson R. Regeneration of parotid acinar cells after high irradiation doses. A morphological study in the rat. Acta Oncol 1995; 34: 193-7.
19. Franzén L, Forsgren S, Gustafsson H, Henriksson R. Irradiation-induced effects on the innervation of rat salivary glands: Changes in enkephalin- and bombesin-like immunoreactivity in ganglionic cells and intraglandular nerve fibers. Cell Tissue Res. 1993; 271: 529-36.
20. Aalto Y, Forsgren S. Kjörell U, Franzén L, Gustafsson H. Henriksson R. Time- and dose-related changes in the expression of substance P in salivary glands in response to fractionated irradiation. Int J Radiat Oncol Biol Phys 1995; 33: 297-305.
21. Moll R, Franke WW, Schiller DL, Geiger B, Krepler R. The catalog of human cytokeratins: patterns of expression in normal epithelia. tumors and cultured cells. Cell 1982; 31: 11-24.
22. Achtstätter T, Moll R, Anderson A, et al. Expression of glial filament protein (GFP) in nerve sheath and non-neural cells re-examined using monoclonal antibodies, with special emphasis on the co-expression of GFP and cytokeratins in epithelial cells of human salivary gland and pleomorphic adenomas. Differentiation 1986; 31: 206-27.
23. Gustafsson H, Bergman F, Virtanen I, Thornell LE. Myoepithelial cells in salivary gland neoplasms. APMIS 1989; 97: 49-55.
24. Gustafsson H. Salivary gland neoplasms. Studies on the cytoskeleton, the secretory apparatus and the nuclear content Umeå University Medical dissertations, Umeå 1986.
25. Born IA, Schwechheimer K, Maier H, Otto HF. Cytokeratin expression in normal salivary glands and in cystadenomas demonstrated by monoclonal antibodies against selective cytokeratin polypeptides. Virchows Arch A (Pathol Anat) 1987; 411: 583-9.
26. Ramaekers FCS, Puts JJG, Moesker O, Jap PHK, Vooijs GP. Use of antibodies to intermediate filaments in the characterization of human tumours. Cold Spring Harbor Symp Quant Biol 1985; 46: 331-9.
27. Virtanen I, Miettinen M. Lehto V-P, et al. Diagnostic application of monoclonal antibodies to intermediate filaments. Ann NY Acad Sci 1985; 455: 635-48.
28. Bloom GD, Carlsöö B, Gustafsson H. lntraacinar nerve terminals in four rodent parotid glands. Acta Anatomica 1977; 97: 291-9.
29. Gustafsson H, Kjörell U. Carlsöö B. Cytoskeletal proteins in oneocytic tumors of the parotid gland. Arch Otolaryngol 1985; 111: 99-105.
30. Kjörell U, Östberg Y. Distribution of intermediate filaments and actin microfilaments in parotid autoimmune sialoadenitis of Sjögren's syndrome. Histopathology 1984; 8: 991-1011.