Interleukin-6 and small intestinal luminal immunoglobulins

Digestive Diseases and Sciences

Volumn 43, Issue 2, 1998, Pages 442-445

  Riordan, Stephen M ^a   McIver, Christopher J ^b   Wakefield, Denis ^b   Thomas, Mervyn C ^b   Duncombe, Vic M ^b   Bolin, Terry D ^b  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b NONE

Author keywords

Interleukin 6; Luminal immunoglobulins; Small intestine

Indexed keywords

IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN A1; IMMUNOGLOBULIN A2; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; IMMUNOGLOBULIN M; INTERLEUKIN 6;

ADULT; ARTICLE; BACTERIAL OVERGROWTH; CHRONIC DIARRHEA; CLINICAL ARTICLE; DYSPEPSIA; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; INTESTINE SECRETION; IRRITABLE COLON; PRIORITY JOURNAL; SMALL INTESTINE MUCOSA;

ADULT; AGED; AGED, 80 AND OVER; COLONIC DISEASES, FUNCTIONAL; DIARRHEA; DYSPEPSIA; HUMANS; IMMUNOGLOBULINS; INTERLEUKIN-6; INTESTINAL DISEASES; INTESTINAL MUCOSA; INTESTINE, SMALL; LINEAR MODELS; MIDDLE AGED;

EID: 0031893304     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018891313829     Document Type: Article

References (25)

1. Kishimoto T, Hirano T: Molecular regulation of B lymphocyte response. Annu Rev Immunol 6:485-512, 1988
2. McGhee JF, Mestecky J, Elson CO, Kiyono H: Regulation of IgA synthesis and immune response by T cells and interleukins. J Clin Immunol 9:175-199, 1989
3. Biewenga J, Van Rees EP, Sminia T: Induction and regulation of IgA responses in the microenvironment of the gut. Clin Immunol Immunopathol 67:1-7, 1993
4. McGhee JR, Beagley KW, Eldridge JH, Fujihashi K, Lue C, Moldoveanu Z, Mestecky J, Radl, J, Kiyono, M: Interleukin cascade for the regulation of IgA synthesis and immune responses. Protides Biol Fluids 36:183-191, 1989
5. Williams RC, Gibbons RJ: Inhibition of bacterial adherence by secretory immunoglobulin A: A mechanism of antigen disposal. Science 177:697-699, 1972
6. Fubara ES, Freter R: Protection against enteric bacterial infection by secretory IgA antibodies. J Immunol 111:395-400, 1973
7. Brandtzaeg P, Halstensen TS, Kett K, Krajci P, Kvale D, Rognum TO, Scott M. Sollid LM: Immunobiology and immunopathology of human gut mucosa: Humoral immunity and intraepithelial lymphocytes. Gastroenterology 97:1562-1584, 1989
8. 14C-D-xylose breath test for detecting bacterial overgrowth in gastrointestinal motility disorders. Scand J Gastroenterol 28:963-968, 1993
9. Simon GL, Gorbach SL: The human intestinal microflora. Dig Dis Sci 31(suppl):147-162, 1986
10. Kirsch G: Bacterial overgrowth. Am J Gastroenterol 85:231-237, 1990
11. Riordan SM, McIver CJ, Bolin TD, Duncombe VM: Fasting breath hydrogen concentrations in gastric and small intestinal bacterial overgrowth. Scand J Gastroenterol 30:252-257, 1995
12. Morson BC, Dawson IMP, Day DW, Jass JR, Price AB, Williams GT: Gastrointestinal Pathology, 3rd ed. Oxford, Blackwell Scientific Publications, 1990
13. Meillet D, Kapel N, Favennec L, Raichvarg G, Savel J, Gobert JG: Correction factors for single radial immunodiffusion and electroimmunodiffusion assays of IgA in secretory fluids. Clin Chim Acta 214:235-241, 1993
14. James SP, Fiocchi C, Graeff AS, Strober W: Immunoregulatory function of lamina propria T cells in Crohn's disease. Gastroenterology 88:1143-1150, 1985
15. Gomez-Guerrero C, Lopez-Armada MJ, Gonzalez E, Egido J: Soluble IgA and IgG aggregates are catabolised by cultured rat mesangial cells and induce production of TNF-α and IL-6, and proliferation. J Immunol 153:5247-5255, 1994
16. Daynes RA, Araneo BA, Ershler WB, Maloney C, Li GZ, Ryu SY: Altered regulation of IL-6 production with normal aging. J Immunol 150:5219-5230, 1993
17. Mestecky J, Lue C, Tarkowski A, Ladjeva I, Peterman JH, Moldoveanu Z, Russell MW, Brown TA, Radl J, Haaijman JJ, Kiyono M, McGhee JR: Comparative studies of the biological properties of human IgA subclasses. Protides Biol Fluids 36:173-182, 1989
18. Kett K, Baklien K, Bakken A, Kral JG, Fausa O, Brandtzaeg P: Intestinal B-cell isotype response to local bacterial load: Evidence for immunoglobulin A subclass adaptation. Gastroenterology 109:819-825, 1995
19. MacDermott RP, Nahm MH: Expression of human immunoglobulin G subclasses in inflammatory bowel disease. Gastroenterology 93:1127-1134, 1987
20. Mosmann TR, Moore KW: The role of IL-10 in cross regulation of TH1 and TH2 responses. Immunol Today 12:49-53, 1991
21. Targan SR: The lamina propria: A dynamic, complex mucosal compartment. Ann NY Acad Sci 664:61-68, 1992
22. Gordon JR, Burd PR, Galli SJ: Mast cells as a source of multifunctional cytokines. Immunol Today 11:458-464, 1990
23. 2-interferon by tumour necrosis factor: A homeostatic mechanism in the control of cell proliferation. Cell 45:659-666, 1986
24. Jirik FR, Podor TJ, Hirano T, Kishimoto T, Loskutoff DJ, Carson DA, Lotz M: Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells. J Immunol 142:144-147, 1989
25. Shirota K, Le Duy L, Yuan SY, Jothy S: Interleukin-6 and its receptor are expressed in human intestinal epithelial cells. Virchows Arch B Cell Pathol 58:303-308, 1990