-
1
-
-
0027239503
-
Antitumor and antimetastatic activity of interleukin 12 against murine tumors
-
Brunda, M. J., L. Luistro, R. R. Warrier, R. B. Wright, B. R. Hubbard, M. Murphy, S. F. Wolf, and M. K. Gately. 1993. Antitumor and antimetastatic activity of interleukin 12 against murine tumors. J. Exp. Med. 178:1223.
-
(1993)
J. Exp. Med.
, vol.178
, pp. 1223
-
-
Brunda, M.J.1
Luistro, L.2
Warrier, R.R.3
Wright, R.B.4
Hubbard, B.R.5
Murphy, M.6
Wolf, S.F.7
Gately, M.K.8
-
2
-
-
0027963161
-
Recombinant IL-12 administration induces tumor regression in association with IFN-γ production
-
Nastala, C. L., H. D. Edington, T. G. McKinney, H. Tahara, M. A. Nalesnik, M. J. Brunda, M. K. Gately, S. F. Wolf, R. D. Schreiber, W. J. Storkus, and M. T. Lotze. 1994. Recombinant IL-12 administration induces tumor regression in association with IFN-γ production. J. Immunol. 153:1697.
-
(1994)
J. Immunol.
, vol.153
, pp. 1697
-
-
Nastala, C.L.1
Edington, H.D.2
McKinney, T.G.3
Tahara, H.4
Nalesnik, M.A.5
Brunda, M.J.6
Gately, M.K.7
Wolf, S.F.8
Schreiber, R.D.9
Storkus, W.J.10
Lotze, M.T.11
-
3
-
-
0029090220
-
Administration of recombinant interleukin 12 prevents outgrowth of tumor cells metastasizing spontaneously to lung and lymph nodes
-
Mu, J., J.-P. Zou, N. Yamamoto, T. Tsutsui, X.-G. Tai, M. Kobayashi, S. Herrmann, H. Fujiwara, and T. Hamaoka. 1995. Administration of recombinant interleukin 12 prevents outgrowth of tumor cells metastasizing spontaneously to lung and lymph nodes. Cancer Res. 55:4404.
-
(1995)
Cancer Res.
, vol.55
, pp. 4404
-
-
Mu, J.1
Zou, J.-P.2
Yamamoto, N.3
Tsutsui, T.4
Tai, X.-G.5
Kobayashi, M.6
Herrmann, S.7
Fujiwara, H.8
Hamaoka, T.9
-
4
-
-
0028944328
-
Influence of interleukin 12 on p53 peptide vaccination against established Meth A sarcoma
-
Noguchi, Y., E. C. Richards, Y.-T. Chen, and L. J. Old. 1995. Influence of interleukin 12 on p53 peptide vaccination against established Meth A sarcoma. Proc. Natl. Acad. Sci. USA 92:2219.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 2219
-
-
Noguchi, Y.1
Richards, E.C.2
Chen, Y.-T.3
Old, L.J.4
-
5
-
-
0031110368
-
IL-12 induces T helper 1-directed antitumor response
-
Tsung, K., J. B. Meko, G. R. Peplinski, Y. Tsung, and J. A. Norton. 1997. IL-12 induces T helper 1-directed antitumor response. J. Immunol. 158:3359.
-
(1997)
J. Immunol.
, vol.158
, pp. 3359
-
-
Tsung, K.1
Meko, J.B.2
Peplinski, G.R.3
Tsung, Y.4
Norton, J.A.5
-
6
-
-
43949163341
-
Interleukin-12 and its role in the generation of T cells
-
Trinchieri, G. 1993. Interleukin-12 and its role in the generation of T cells. Immunol. Today 14:335.
-
(1993)
Immunol. Today
, vol.14
, pp. 335
-
-
Trinchieri, G.1
-
7
-
-
0025875022
-
Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells
-
Wolf, S. F., P. A. Temple, M. Kobayashi, D. Young, M. Dicig, L. Lowe, R. Dzialo, L. Fitz, C. Ferenz, R. M. Hewick, K. Kelleher, S. H. Herrmann, S. C. Clark, L. Azzoni, S. H. Chan, G. Trinchieri, and B. Perussia. 1991. Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells. J. Immunol. 146:3074.
-
(1991)
J. Immunol.
, vol.146
, pp. 3074
-
-
Wolf, S.F.1
Temple, P.A.2
Kobayashi, M.3
Young, D.4
Dicig, M.5
Lowe, L.6
Dzialo, R.7
Fitz, L.8
Ferenz, C.9
Hewick, R.M.10
Kelleher, K.11
Herrmann, S.H.12
Clark, S.C.13
Azzoni, L.14
Chan, S.H.15
Trinchieri, G.16
Perussia, B.17
-
8
-
-
0027491655
-
Interleukin 12 acts directly on CD4 T cells to enhance priming for interferon γ production and diminishes interleukin 4 inhibition of such priming
-
Seder, R. A., R. Gazzinelli, A. Sher, and W. E. Paul. 1993. Interleukin 12 acts directly on CD4 T cells to enhance priming for interferon γ production and diminishes interleukin 4 inhibition of such priming. Proc. Natl. Acad. Sci. USA 90:10188.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10188
-
-
Seder, R.A.1
Gazzinelli, R.2
Sher, A.3
Paul, W.E.4
-
9
-
-
0028593449
-
Interleukin 12 induces the differentiation of major histocompatibility complex class I-primed cytotoxic T-lymphocyte precursors into allospecific cytotoxic effectors
-
Chouaib, S., J. Chehimi, L. Bani, N. Genetet, T. Tursz, F. Gay, G. Trinchieri, and F. Mami-Chouaib. 1994. Interleukin 12 induces the differentiation of major histocompatibility complex class I-primed cytotoxic T-lymphocyte precursors into allospecific cytotoxic effectors. Proc. Natl. Acad. Sci. USA 91:12659.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12659
-
-
Chouaib, S.1
Chehimi, J.2
Bani, L.3
Genetet, N.4
Tursz, T.5
Gay, F.6
Trinchieri, G.7
Mami-Chouaib, F.8
-
10
-
-
0029922177
-
Inhibition of Angiogenesis by interleukin-12 is mediated by the γ interferon-inducible protein 10
-
Sgadari, C., A. L. Angiolillo, and G. Tosato. 1996. Inhibition of Angiogenesis by interleukin-12 is mediated by the γ interferon-inducible protein 10. Blood 87: 3877.
-
(1996)
Blood
, vol.87
, pp. 3877
-
-
Sgadari, C.1
Angiolillo, A.L.2
Tosato, G.3
-
11
-
-
0027309318
-
Resolution of cutaneous leishmaniasis: Interleukin 12 initiates a protective T helper type 1 immune response
-
Sypek, J. P., C. L. Chung, S. E. H. Mayor, J. M. Subramanyam, S. J. Goldman, D. S. Sieburth, S. F. Wolf, and R. G. Schaub. 1993. Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response. J. Exp. Med. 177:1797.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1797
-
-
Sypek, J.P.1
Chung, C.L.2
Mayor, S.E.H.3
Subramanyam, J.M.4
Goldman, S.J.5
Sieburth, D.S.6
Wolf, S.F.7
Schaub, R.G.8
-
12
-
-
0031112653
-
Immunity to chlamydia trachomatis is mediated by T helper 1 cells through IFNγ-dependent and -independent pathways
-
Perry, L. L., K. Feilzer, and H. D. Caldwell. 1997. Immunity to chlamydia trachomatis is mediated by T helper 1 cells through IFNγ-dependent and -independent pathways. J. Immunol. 158:3344.
-
(1997)
J. Immunol.
, vol.158
, pp. 3344
-
-
Perry, L.L.1
Feilzer, K.2
Caldwell, H.D.3
-
13
-
-
0030895747
-
Intracellular antimicrobial activity in the absence of interferon-γ: Effect of interleukin-12 in experimental visceral leishmaniasis in interferon-γ gene-disrupted mice
-
Taylor, A. P., and H. W. Murray. 1997. Intracellular antimicrobial activity in the absence of interferon-γ: effect of interleukin-12 in experimental visceral leishmaniasis in interferon-γ gene-disrupted mice. J. Exp. Med. 185:1231.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1231
-
-
Taylor, A.P.1
Murray, H.W.2
-
14
-
-
0017157153
-
Enhancement of delayed hypersensitivity by depletion of suppressor T cells with cyclophosphamide in mice
-
Mitsuoka, A., M. Baba, and S. Morikawa. 1976. Enhancement of delayed hypersensitivity by depletion of suppressor T cells with cyclophosphamide in mice. Nature 262:77.
-
(1976)
Nature
, vol.262
, pp. 77
-
-
Mitsuoka, A.1
Baba, M.2
Morikawa, S.3
-
15
-
-
0017210393
-
Kinetic aids to proper chemotherapeutic scheduling: Labeled nucleoside incorporation studies in vivo
-
Young, R. C. 1976. Kinetic aids to proper chemotherapeutic scheduling: labeled nucleoside incorporation studies in vivo. Cancer Treat. Rep. 60:1947.
-
(1976)
Cancer Treat. Rep.
, vol.60
, pp. 1947
-
-
Young, R.C.1
-
16
-
-
0018886371
-
Importance of timing in cyclophosphamide therapy of MOPC-315 tumor-bearing mice
-
Hengst, J. C. D., M. B. Mokyr, and S. Dray. 1980. Importance of timing in cyclophosphamide therapy of MOPC-315 tumor-bearing mice. Cancer Res. 40: 2135.
-
(1980)
Cancer Res.
, vol.40
, pp. 2135
-
-
Hengst, J.C.D.1
Mokyr, M.B.2
Dray, S.3
-
17
-
-
0024598609
-
Cyclophosphamide-induced immunologically mediated regression of a cyclophosphamide-resistant murine tumor: A consequence of eliminating precursor L3T4 suppressor T-cells
-
Awwad, M., and R. J. North. 1989. Cyclophosphamide-induced immunologically mediated regression of a cyclophosphamide-resistant murine tumor: a consequence of eliminating precursor L3T4 suppressor T-cells. Cancer Res. 49:1649.
-
(1989)
Cancer Res.
, vol.49
, pp. 1649
-
-
Awwad, M.1
North, R.J.2
-
18
-
-
0028827360
-
Role of interferon-γ in interleukin 12-induced pathology in mice
-
Car, B. D., V. M. Eng, B. Schnyder, M. LeHir, A. N. Shakhov, G. Woerly, S. Huang, M. Aguet, T. D. Anderson, and B. Ryffel. 1995. Role of interferon-γ in interleukin 12-induced pathology in mice. Am. J. Pathol 147:1693.
-
(1995)
Am. J. Pathol
, vol.147
, pp. 1693
-
-
Car, B.D.1
Eng, V.M.2
Schnyder, B.3
LeHir, M.4
Shakhov, A.N.5
Woerly, G.6
Huang, S.7
Aguet, M.8
Anderson, T.D.9
Ryffel, B.10
-
19
-
-
0029990630
-
Molecular mechanisms underlying IFN-γ mediated tumor growth inhibition induced during tumor immunotherapy with rIL-12
-
Yu, W.-G., N. Yamamoto, H. Takenaka, J. Mu, X.-G. Tai, J.-P. Zou, M. Ogawa, T. Tsutsui, R. Wijesuriya, R. Yoshida, S. Herrmann, H. Fujiwara, and T. Hamaoka. 1996. Molecular mechanisms underlying IFN-γ mediated tumor growth inhibition induced during tumor immunotherapy with rIL-12. Int. Immunol. 8:855.
-
(1996)
Int. Immunol.
, vol.8
, pp. 855
-
-
Yu, W.-G.1
Yamamoto, N.2
Takenaka, H.3
Mu, J.4
Tai, X.-G.5
Zou, J.-P.6
Ogawa, M.7
Tsutsui, T.8
Wijesuriya, R.9
Yoshida, R.10
Herrmann, S.11
Fujiwara, H.12
Hamaoka, T.13
-
20
-
-
0030070446
-
Cytokine and chemokine expression in tumors of mice receiving systemic therapy with IL-12
-
Tannenbaum, C. S., N. Wicker, D. Armstrong, R. Tubbs, J. Finke, R. M. Bukowski, and T. A. Hamilton. 1996. Cytokine and chemokine expression in tumors of mice receiving systemic therapy with IL-12. J. Immunol. 156:693.
-
(1996)
J. Immunol.
, vol.156
, pp. 693
-
-
Tannenbaum, C.S.1
Wicker, N.2
Armstrong, D.3
Tubbs, R.4
Finke, J.5
Bukowski, R.M.6
Hamilton, T.A.7
-
21
-
-
0018821195
-
Further observations on the effect of cyclophosphamide on intratumor and peripheral leukocyte levels
-
Evans, R. 1980. Further observations on the effect of cyclophosphamide on intratumor and peripheral leukocyte levels. Am. J. Pathol. 99:667.
-
(1980)
Am. J. Pathol.
, vol.99
, pp. 667
-
-
Evans, R.1
-
22
-
-
0018927731
-
Macrophage accumulation in murine ascites tumors: Cytoxan-induced dominance of macrophages over tumor cells and the anti-tumor effect of endotoxin
-
Dye, E. S., and R. J. North. 1980. Macrophage accumulation in murine ascites tumors: Cytoxan-induced dominance of macrophages over tumor cells and the anti-tumor effect of endotoxin. J. Immunol. 125:1650.
-
(1980)
J. Immunol.
, vol.125
, pp. 1650
-
-
Dye, E.S.1
North, R.J.2
-
23
-
-
0030067276
-
Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal carcinoma
-
Wigginton, J. M., K. L. Komschlies, T. C. Back, J. L. Franco, M. J. Brunda, and R. H. Wiltrout. 1996. Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal carcinoma. J. Natl. Cancer Inst. 88:38.
-
(1996)
J. Natl. Cancer Inst.
, vol.88
, pp. 38
-
-
Wigginton, J.M.1
Komschlies, K.L.2
Back, T.C.3
Franco, J.L.4
Brunda, M.J.5
Wiltrout, R.H.6
-
24
-
-
0025058783
-
Unique tumor-associated antigen identified by tumor infiltrating lymphocytes
-
Barth, R. J., S. N. Bock, J. J. Mule and S. A. Rosenberg. 1990. Unique tumor-associated antigen identified by tumor infiltrating lymphocytes. J. Immunol. 144: 1531.
-
(1990)
J. Immunol.
, vol.144
, pp. 1531
-
-
Barth, R.J.1
Bock, S.N.2
Mule, J.J.3
Rosenberg, S.A.4
-
25
-
-
0031586038
-
Treatment of subcutaneous tumor with adoptively transferred T cells
-
Peng, L., S. S. Shu, and J. C. Krauss. 1997. Treatment of subcutaneous tumor with adoptively transferred T cells. Cell. Immunol. 178:24.
-
(1997)
Cell. Immunol.
, vol.178
, pp. 24
-
-
Peng, L.1
Shu, S.S.2
Krauss, J.C.3
-
26
-
-
0018214808
-
The immunological basis of endotoxin-induced tumor regression
-
Berendt, M. J., R. J. North, and D. P. Kirstein. 1978. The immunological basis of endotoxin-induced tumor regression. J. Exp. Med. 148:1560.
-
(1978)
J. Exp. Med.
, vol.148
, pp. 1560
-
-
Berendt, M.J.1
North, R.J.2
Kirstein, D.P.3
-
27
-
-
0030051658
-
Regulation of murine macrophage IL-12 production
-
Skeen, M. J., M. A. Miller, T. M. Shinnick, and H. K. Ziegler. 1996. Regulation of murine macrophage IL-12 production. J. Immunol. 156:1196.
-
(1996)
J. Immunol.
, vol.156
, pp. 1196
-
-
Skeen, M.J.1
Miller, M.A.2
Shinnick, T.M.3
Ziegler, H.K.4
-
28
-
-
0028819323
-
Systemic treatment with interleukin-4 induces regression of pulmonary metastases in a murine renal cell carcinoma model
-
Hillman, G. G., E. Younes, D. Visscher, E. Ali, J. S. Lam, E. Montecillo, J. E. Pontes, G. P. Hasa, and R. K. Puri. 1995. Systemic treatment with interleukin-4 induces regression of pulmonary metastases in a murine renal cell carcinoma model. Cell. Immunol. 160:257.
-
(1995)
Cell. Immunol.
, vol.160
, pp. 257
-
-
Hillman, G.G.1
Younes, E.2
Visscher, D.3
Ali, E.4
Lam, J.S.5
Montecillo, E.6
Pontes, J.E.7
Hasa, G.P.8
Puri, R.K.9
-
29
-
-
0023892504
-
Improved therapeutic effects of interleukin 2 after the accumulation of lymphokine-activated killer cells in tumor tissue of mice previously treated with cyclophosphamide
-
Hosokawa, M., Y. Sawamura, T. Morkage, F. Okada, Z.-Y. Xu, K. Morikawa, K. Itoh, and H. Kobayashi. 1988. Improved therapeutic effects of interleukin 2 after the accumulation of lymphokine-activated killer cells in tumor tissue of mice previously treated with cyclophosphamide. Cancer Immunol. Immunother. 26:250.
-
(1988)
Cancer Immunol. Immunother.
, vol.26
, pp. 250
-
-
Hosokawa, M.1
Sawamura, Y.2
Morkage, T.3
Okada, F.4
Xu, Z.-Y.5
Morikawa, K.6
Itoh, K.7
Kobayashi, H.8
-
30
-
-
0024582623
-
Chemo-immunotherapy of murine tumors using interleukin-2(IL-2) and cyclophosphamide
-
Kedar, E., R. Ben-Aziz, E. Epstein, and B. Leshem. 1989. Chemo-immunotherapy of murine tumors using interleukin-2(IL-2) and cyclophosphamide. Cancer Immunol. Immunother. 29:74.
-
(1989)
Cancer Immunol. Immunother.
, vol.29
, pp. 74
-
-
Kedar, E.1
Ben-Aziz, R.2
Epstein, E.3
Leshem, B.4
-
31
-
-
0023215197
-
In vivo resistance of secondary antitumor immune response to cyclophosphamide: Effects on T cell subsets
-
Peppoloni, S., B. J. Mathieson, R. B. Herberman, R. W. Overton, and E. Gorelik. 1987. In vivo resistance of secondary antitumor immune response to cyclophosphamide: effects on T cell subsets. Cancer Immunol. Immunother. 24:49.
-
(1987)
Cancer Immunol. Immunother.
, vol.24
, pp. 49
-
-
Peppoloni, S.1
Mathieson, B.J.2
Herberman, R.B.3
Overton, R.W.4
Gorelik, E.5
-
32
-
-
0021273272
-
Adoptive immunization against an established tumor with cytolytic versus memory T cells
-
Dye, E. S., and R. J. North. 1984. Adoptive immunization against an established tumor with cytolytic versus memory T cells. Transplantation 37:600.
-
(1984)
Transplantation
, vol.37
, pp. 600
-
-
Dye, E.S.1
North, R.J.2
-
33
-
-
0019993698
-
Effects of cyclophosphamide on murine bone marrow and splenic megakaryocyte-CFC, granulocyte-macrophage-CFC, and peripheral blood cell levels
-
Yeager, A. M., F. C. Levin, and J. Levin. 1982. Effects of cyclophosphamide on murine bone marrow and splenic megakaryocyte-CFC, granulocyte-macrophage-CFC, and peripheral blood cell levels. J. Cell. Physiol. 112:222.
-
(1982)
J. Cell. Physiol.
, vol.112
, pp. 222
-
-
Yeager, A.M.1
Levin, F.C.2
Levin, J.3
-
34
-
-
0018818370
-
Relative susceptibilities of T cell subsets involved in delayed-type hypersensitivity to sheep red blood cells to the in vitro action of 4-hydroperoxycyclophosphamide
-
Kaufmann, S. H. E., H. Hahn, and T. Diamantstein. 1980. Relative susceptibilities of T cell subsets involved in delayed-type hypersensitivity to sheep red blood cells to the in vitro action of 4-hydroperoxycyclophosphamide. J. Immunol. 125: 1104.
-
(1980)
J. Immunol.
, vol.125
, pp. 1104
-
-
Kaufmann, S.H.E.1
Hahn, H.2
Diamantstein, T.3
-
35
-
-
0027075937
-
IL-12 augments antigen-dependent proliferation of activated T lymphocytes
-
Bertagnolli, M. M., B.-Y. Lin, D. Young, and S. H. Herrmann. 1992. IL-12 augments antigen-dependent proliferation of activated T lymphocytes. J. Immunol. 149:3778.
-
(1992)
J. Immunol.
, vol.149
, pp. 3778
-
-
Bertagnolli, M.M.1
Lin, B.-Y.2
Young, D.3
Herrmann, S.H.4
|