Saturated Heterocycles. 254 [1]. Synthesis and Stereo-chemistry of Saturated or Partially Saturated Pyridazino-[6,1-b]- and Phthalazino[1,2-b]quinazolinones

Journal of Heterocyclic Chemistry

Volumn 35, Issue 1, 1998, Pages 201-208

  Bernáth, Gábor ^a   Miklós, Ferenc ^a   Stájer, Géza ^a   Sohár, Pal ^b   Böcskei, Zsolt ^b   Menyhárd, Dóra ^b  

^a UNIVERSITY OF SZEGED   (Hungary)

^b EÖTVÖS LORÁND UNIVERSITY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOBICYCLO[2.2.1]HEPTANE 2 CARBOXYLIC ACID; CYCLOALKANE; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE; HETEROCYCLIC COMPOUND; HYDRAZIDE; HYDRAZIDE DERIVATIVE; LACTAM DERIVATIVE; PHTHALAZINE DERIVATIVE; PYRIDAZINE DERIVATIVE; QUINAZOLINONE DERIVATIVE;

ARTICLE; CHEMICAL REACTION; DRUG ACTIVITY; DRUG SYNTHESIS; ISOMER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0031893098     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570350138     Document Type: Article

References (40)

1. Part 253: R. Sillanpää, E. Forró, F. Fülöp, G. Bernáth, Acta Chem. Scand., submitted for publication; Part 252; F. Fülöp, J. Tari, G. Bernáth, P. Sohár, A. Dancsó, Gy. Argay and A. Kálmán, Liebigs Ann. Chem., 34, 289 (1997); Part 251: F. Fülöp, E. Forró, G. Bernáth, I. Miskolczi, A. Martinsen and P. Vainiotalo: J. Heterocyclic Chem., 34, 1167 (1997).
2. Part 253: R. Sillanpää, E. Forró, F. Fülöp, G. Bernáth, Acta Chem. Scand., submitted for publication; Part 252; F. Fülöp, J. Tari, G. Bernáth, P. Sohár, A. Dancsó, Gy. Argay and A. Kálmán, Liebigs Ann. Chem., 34, 289 (1997); Part 251: F. Fülöp, E. Forró, G. Bernáth, I. Miskolczi, A. Martinsen and P. Vainiotalo: J. Heterocyclic Chem., 34, 1167 (1997).
3. Part 253: R. Sillanpää, E. Forró, F. Fülöp, G. Bernáth, Acta Chem. Scand., submitted for publication; Part 252; F. Fülöp, J. Tari, G. Bernáth, P. Sohár, A. Dancsó, Gy. Argay and A. Kálmán, Liebigs Ann. Chem., 34, 289 (1997); Part 251: F. Fülöp, E. Forró, G. Bernáth, I. Miskolczi, A. Martinsen and P. Vainiotalo: J. Heterocyclic Chem., 34, 1167 (1997).
4. G. Bernáth, Bull. Soc. Chim. Belg., 103, 509 (1994).
5. P. Sohár, G. Stájer, A. E. Szabó and G. Bernáth, J. Mol. Struct., 382, 187 (1996).
6. A. E. Szabó, G. Stájer, P. Sohár, R. Sillanpää and G. Bernáth, Acta Chem. Scand., 49, 751 (1995).
7. G. Stájer, A. E. Szabó, G. Bernáth and P. Sohár, Heterocycles, 38, 1061 (1994).
8. H. Orzalesi, P. Chevallet, G. Berge, M. Boucard, J. J. Serrano, G. Privat and C. Andrary, Eur. J. Med. Chem.-Chim. Ther., 13, 259 (1978).
9. A. Mertens, H. Zilch, B. König, W. Schäfer, T. Poll, W. Kampe, H. Seidel, V. Leser and H. Leinert, J. Med. Chem., 36, 2526 (1993).
10. V. Pestellini, M. Ghelardoni, G. Volterra and P. Del Soldato, Eur. J. Med. Chem.-Chim. Ther., 13, 296 (1978).
11. C. F. Schwender, B. R. Sunday, J. J. Kerbleski and D. J. Herzig, J. Med. Chem., 23, 964 (1980).
12. M. Lamchen, J. Chem. Soc. C, 573 (1996) and references therein.
13. V. Pestellini, M. Ghelardoni, C. Bianchini and A. Liquori, Boll. Chim. Farm., 117, 54 (1978).
14. F. K. Kirchner and A. W. Zalay, U. S. patent 3,843,654, 1974; Chem. Abstr., 82, 112098n (1975).
15. F. K. Kirchner and A. W. Zalay, U. S. patent 3,843,654, 1974; Chem. Abstr., 82, 112098n (1975).
16. M. Razvi, T. Ramalingam and P. B. Sattur, Indian J. Chem., 29B, 399 (1990).
17. M. A. I. Salem, A. M. El-Gendy and S. I. Nagdy, Rev. Roumain. Chim., 31, 9 (1989).
18. F. A. Khalifa, Archiv Pharm. (Weinheim), 323, 883 (1990).
19. V. Balasubramaniyan and N. P. Argade, Indian J. Chem., 27B, 906 (1988).
20. W. L. F. Armarego and T. Kobayashi, J. Chem. Soc. C, 1635 (1969).
21. D. T. Pegg, D. M. Doddrell and M. R. Bendall, J. Chem. Phys., 77, 2745 (1982).
22. R. R. Ernst, G. Bodenhausen and A. Wokaun, Principles of Nuclear Magnetic Resonance in One and Two Dimensions, Clarendon Press, Oxford, 1987, pp 471-479.
23. P. Sohár, Nuclear Magnetic Resonance Spectroscopy, CRC Press, Boca Raton, Florida, 1983, [a] Vol 1, pp 196, 197; [b] Vol 2, pp 89-90; Vol 2, pp 25-27; Vol 1, pp 38-41; [e] Vol 2, pp 154, 155.
24. P. Sohár, Nuclear Magnetic Resonance Spectroscopy, CRC Press, Boca Raton, Florida, 1983, [a] Vol 1, pp 196, 197; [b] Vol 2, pp 89-90; Vol 2, pp 25-27; Vol 1, pp 38-41; [e] Vol 2, pp 154, 155.
25. P. Sohár, Nuclear Magnetic Resonance Spectroscopy, CRC Press, Boca Raton, Florida, 1983, [a] Vol 1, pp 196, 197; [b] Vol 2, pp 89-90; Vol 2, pp 25-27; Vol 1, pp 38-41; [e] Vol 2, pp 154, 155.
26. P. Sohár, Nuclear Magnetic Resonance Spectroscopy, CRC Press, Boca Raton, Florida, 1983, [a] Vol 1, pp 196, 197; [b] Vol 2, pp 89-90; Vol 2, pp 25-27; Vol 1, pp 38-41; [e] Vol 2, pp 154, 155.
27. P. Sohár, Nuclear Magnetic Resonance Spectroscopy, CRC Press, Boca Raton, Florida, 1983, [a] Vol 1, pp 196, 197; [b] Vol 2, pp 89-90; Vol 2, pp 25-27; Vol 1, pp 38-41; [e] Vol 2, pp 154, 155.
28. J. K. M. Sanders and J. D. Mersch, Prog Nucl. Magn. Reson., 15, 353 (1982) and references cited therein.
29. M. J. Karplus, Chem. Phys., 30, 11, (1959); Chem. Phys., 33, 1842 (1960).
30. M. J. Karplus, Chem. Phys., 30, 11, (1959); Chem. Phys., 33, 1842 (1960).
31. D. M. Grant and B. V. Cheney, J. Am. Chem. Soc., 89, 5315 (1967).
32. P. Sohár, G. Stájer and G. Bernáth, Org. Magn. Reson., 21, 512 (1983).
33. M. R. Bendall, D. M. Doddrell, D. T. Pegg and W. E. Hull, High Resolution Multipulse NMR Spectra Editing and DEPT, Bruker, Karlsruhe, 1982.
34. G. M. Sheldrick, Acta Cryst., A46, 467 (1990).
35. P. T. Beurskens et al., Ed, The DIRDIF Program System, Technical Report of the Crystallography Laboratory, Toernooiveld, p 6525, Nijmegen, The Netherlands, 1984.
36. G. M. Sheldrick, SHELXL-93 Program for the Refinement of Crystal Structures, University of Göttingen, Germany, 1993.
37. TEXSAN TEXRAY, Crystal Structure Analysis Package, Version 1.6, Molecular Structure Corporation, The Woodlands, Texas, 1985 & 1992.
38. G. Stájer, A. E. Szabó, F. Fülöp, G. Bernáth and P. Sohár, Chem. Ber., 120, 259 (1987).
39. L. F. Fieser, F. C. Novello, J. Am. Chem. Soc., 64, 802 (1942).
40. G. Stájer, F. Csende, G. Bernáth, P. Sohár and J. Szúnyog, Monatsh. Chem., 125, 923 (1994).