Leucine alters the interaction of the leucine-responsive regulatory protein (Lrp) with the fim switch to stimulate site-specific recombination in Escherichia coli

Molecular Microbiology

Volumn 27, Issue 4, 1998, Pages 751-761

  Roesch, Paula L ^a   Blomfield, Ian C ^a  

^a WAKE FOREST BAPTIST HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEUCINE; REGULATOR PROTEIN;

ARTICLE; BACTERIUM MUTANT; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; ESCHERICHIA COLI; FIMBRIA; GENE EXPRESSION; GENETIC RECOMBINATION; NONHUMAN; OPERON; PRIORITY JOURNAL;

BACTERIAL PROTEINS; BASE SEQUENCE; BINDING SITES; DNA-BINDING PROTEINS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; INTEGRASES; LEUCINE; LEUCINE-RESPONSIVE REGULATORY PROTEIN; MOLECULAR SEQUENCE DATA; RECOMBINATION, GENETIC; TRANSCRIPTION FACTORS;

EID: 0031893034     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1998.00720.x     Document Type: Article

References (41)

1. Abraham, J.M., Freitag, C.S., Clements, J.R., and Eisenstein, B.I. (1985) An invertible element of DNA controls phase variation of type 1 fimbria of Escherichia coli. Proc Natl Acad Sci USA 82: 5724-5727.
2. Argos, P., Landy, A., Abremski, K., Egan, J.B., Haggard-Ljungquist, E., Hoess, R.H., et al. (1986) The integrase family of site-specific recombinases: regional similarities and global diversity. EMBO J 5: 433-440.
3. Blomfield, I.C., Vaughn, V., Rest, R.F., and Eisenstein, B.I. (1991) Allelic exchange in Escherichia coli using the Bacillus subtilis sacB gene and a temperature-sensitive pSC101 replicon. Mol Microbiol 5: 1447-1457.
4. Blomfield, I.C., Calie, PJ., Eberhardt, K.J., MacClain, M.S., and Eisenstein, B.I. (1993) Lrp stimulates the phase variation of type 1 fimbriation in Escherichia coli K-12. J Bacteriol 175: 27-36.
5. Blomfield, I.C., Kulasekara, D.H., and Eisenstein, B.I. (1997) Integration host factor stimulates both FimB- and FimE-mediated site-specific DNA inversion that controls phase variation of type 1 fimbriae expression in Escherichia coli. Mol Microbiol 23: 705-717.
6. Borst, D.W., Blumenthal, R.M., and Matthews, R.G. (1996) Use of an in vivo titration method to study a global regulator: effect of varying Lrp levels on expression of gltBDF in Escherichia coli. J Bacteriol 178: 6904-6912.
7. Braaten, B.A., Platko, J.V., van der Woude, M.W., Simons, B.H., de Graaf, F.K., Calvo, J.M., et al. (1992) Leucine-responsive regulatory protein controls the expression of both pap and fan pili operons in Escherichia coli. Proc Natl Acad Sci USA 89: 4250-4254.
8. Calos, P.M. (1978) DNA sequence for a low-level promoter of the lac represser gene and an 'up' mutation. Nature 274: 762-765.
9. Calvo, J.M., and Matthews, R.G. (1994) The leucine-responsive regulatory protein, a global regulator of metabolism in Escherichia coli. Microbiol Rev 58: 466-490.
10. Gui, Y., Wang, Q., Stormo, G.D., and Calvo, J.M. (1995) A consensus sequence for binding of Lrp to DNA. J Bacteriol 177: 4872-4880.
11. Cui, Y., Midkiff, M.A., Wang, Q., and Calvo, J.M. (1996) The leucine-responsive regulatory protein (Lrp) from Escherichia coli: stoichiometry and minimal requirements for binding DNA. J Biol Chem 271: 6611-6617.
12. Dorman, C.J., and Higgins, C.F. (1987) Fimbrial phase variation in Escherichia coli: dependence on integration host factor and homologies with other site-specific recombinases. J Bacteriol 169: 3840-3843.
13. Echols, H. (1986) Multiple DNA-protein interactions governing high-precision DNA transactions. Science 233: 1050-1056.
14. Eisenstein, B.I., Sweet, D.S., Vaughn, V., and Friedman, D.I. (1987) Integration host factor is required for the DNA inversion that controls phase variation in Escherichia coli. Proc Natl Acad Sci USA 84: 6506-6510.
15. Ernsting, B.R., Denninger, J.W., Blumenthal, R.M., and Matthews, R.G. (1993) Regulation of the gltBDF operon of Escherichia coli: how is a leucine-insensitive operon regulated by the leucine-responsive regulatory protein? J Bacteriol 175: 7160-7169.
16. Gally, D.L., Bogan, J.A., Eisenstein, B.I., and Blomfield, I.C. (1993) Environmental regulation of the fim switch controlling type 1 fimbrial phase variation in Escherichia coli K-12: effects of temperature and media. J Bacteriol 175: 6186-6193.
17. Gally, D.L., Rucker, T.J., and Blomfield, I.C. (1994) The leucine-responsive regulatory protein binds to the fim switch to control phase variation of type 1 fimbrial expression in Escherichia coli K-12. J Bacteriol 176: 5665-5672.
18. Gally, D.L., Leathart, J., and Blomfield, I.C. (1996) Interaction of FimB and FimE with the fim switch that controls the phase variation of type 1 fimbriae in Escherichia coli K-12. Mol Microbiol 21: 725-738.
19. Grosschedl, R. (1995) Higher-order nucleoprotein complexes in transcription: analogies with site-specific recombination. Curr Opin Cell Biol 7: 362-370.
20. Guyer, M.S., Reed, R.R., Steitz, J.A., and Low, K.B. (1981) Identification of a sex-factor-affinity site in E. coli as gamma delta. Cold Spring Harb Symp Quant Biol 45: 135-140.
21. Hamilton, C.M., Aldea, M., Washburn, B.K., Babitzke, P., and Kushner, S.R. (1989) New method for generating deletions and gene replacements in Escherichia coli. J Bacteriol 171: 4617-4622.
22. Hertzberg, R.P., and Dervan, P.B. (1982) Cleavage of DNA with methidiumpropyl-EDTA-iron (II): reaction conditions and product analyses. Biochemistry 23: 3934-3945.
23. Norton, R.M., Ho, S.N., Pullen, J.K., Hunt, H.D., Cai, Z., and Pease, L.R. (1993) Gene splicing by overlap extension. Methods Enzymol 217: 270-279.
24. Klemm, P. (1986) Two regulatory fim genes, fimB and fimE, control the phase variation of type 1 fimbriae in Escherichia coli. EMBO J 5: 1389-1393.
25. Kosturko, L.D., Daub, E., and Murialdo, H. (1989) The interaction of E. coli integration host factor and lambda cos DNA: multiple complex formation and protein-induced bending. Nucleic Acids Res 17: 317-334.
26. Landolfi, N.F., Yin, X., Capra, J.D., and Tucker, P. (1989) Protection analysis (or 'footprinting') of specific protein-DNA complexes in crude nuclear extracts using methidiumpropyl-EDTA-Iron (II). BioTechniques 7: 500-504.
27. Lin, R., Ernsting, B., Hirshfield, I.N., Matthews, R.G., Neidhardt, F.C., Clark, R.L., et al. (1992) The lrp gene product regulates expression of lysU in Escherichia coli K-12. J Bacteriol 174: 2779-2784.
28. Linn, T., and St Pierre, R. (1990) Improved vector system for constructing transcriptional fusions that ensures independent translation of lacZ. J Bacteriol 172: 1077-1084.
29. Neidhardt, F.C., Bloch, P.L., and Smith, D.F. (1974) Culture media for enterobacteria. J Bacteriol 119: 736-747.
30. Newman, E.B., and Lin, R. (1995) Leucine-responsive regulatory protein: a global regulator of gene expression in E. coli. Annu Rev Microbiol 49: 747-775.
31. Oram, M., Szczelkun, M.D., and Halford, S.E. (1995) Pieces of the site-specific recombination puzzle. Curr Biol 5: 1106-1109.
32. Quay, S.C., Dick, T.E., and Oxender, D.L. (1977) Role of transport systems in amino acid metabolism: leucine toxicity and the branched-chain amino acid transport systems. J Bacteriol 129: 1257-1265.
33. Ricca, E., Aker, D.A., and Calvo, J.M. (1989) A protein that binds to the regulatory region of the Escherichia coli ilvIH operon. J Bacteriol 171: 1658-1664.
34. Sadowski, P.D. (1993) Site-specific genetic recombination: hops, flips, and flops. FASEB J 7: 760-767.
35. Silhavy, T.J., Berman, M.L., and Enquist, L.W. (1984) Experiments with Gene Fusions. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
36. Thompson, J.F., and Landy, A. (1988) Empirical estimation of protein-induced DNA bending angles: application to lambda site-specific recombination complexes. Nucleic Acids Res 16: 9687-9705.
37. van der Woude, M.W., and Low, D.A. (1994) Leucine-responsive regulatory protein and deoxyadenosine methylase control the phase variation and expression of the E. coli sfa and daa pili operons. Mol Microbiol 11: 605-618.
38. Wang, Q., and Calvo, J.M. (1993a) Lrp, a major regulatory protein in Escherichia coli, bends DNA and can organize the assembly of a higher-order nucleoprotein structure. EMBO J 12: 2495-2501.
39. Wang, Q., and Calvo, J.M. (1993b) Lrp, a global regulatory protein of Escherichia coli, binds co-operatively to multiple sites and activates transcription of ilvIH. J Mol Biol 229: 306-318.
40. Wiese, II, D.E., Ernsting, B.R., Blumenthal, R.M., and Matthews, R.G. (1997) A nucleoprotein activation complex between the leucine-responsive regulatory protein and DNA upstream of the gltBDF operon in Escherichia coli. J Mol Biol 270: 152-168.
41. Willins, A.K., Ryan, C.W., Platko, J.V., and Calvo, J.M. (1991) Characterization of Lrp, an Escherichia coli regulatory protein that mediates a global response to leucine. J Biol Chem 266: 10768-10774.