Effect of prostaglandins on cyclic AMP production in cultured human ciliary muscle cells

Journal of Ocular Pharmacology and Therapeutics

Volumn 14, Issue 1, 1998, Pages 45-55

  Zhan, G L ^a   Camras, C B ^a   Opere, C ^b   Tang, L ^b   Ohia, S E ^b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b CREIGHTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA;

ARTICLE; CELL CULTURE; CILIARY MUSCLE; HUMAN; HUMAN CELL; INTRAOCULAR PRESSURE; SECOND MESSENGER; SMOOTH MUSCLE FIBER;

EID: 0031892718     PISSN: 10807683     EISSN: None     Source Type: Journal    
DOI: 10.1089/jop.1998.14.45     Document Type: Article

References (36)

1. Ohia, S.E. and Jumblatt, J.E. Prejunctional inhibitory effects of prostanoids on sympathetic neurotransmission in the rabbit iris-ciliary body. J. Pharmacol. Exp. Ther., 255:11-16, 1990.
2. Ohia, S.E. and Jumblatt, J.E. Prejunctional prostaglandin receptors in the human iris-ciliary body. Curr. Eye Res., 10:967-975, 1991.
3. 2 subtype. Invest. Ophthalmol. Vis. Sci., 32:360-365, 1991.
4. Al-zadjali, K.H., Imler, M.P. and Ohia, S.E. Inhibitory effect of prostaglandins on dopamine release from the retina. Gen. Pharmacol., 25:289-296, 1994.
5. Yousufzai, S.Y.K., Ye, Z. and Abdel-Latif, A.A. Muscarinic stimulation of arachidonic acid release and prostaglandin synthesis in bovine ciliary muscle: prostaglandins induce cyclic AMP formation and muscle relaxation. Exp. Eye Res., 58:513-522, 1994.
6. Goh, Y., Hotehama, Y. and Mishima, H.K. Characterization of ciliary muscle relaxation induced by various agents. Invest. Ophthalmol. Vis. Sci., 36:1188-1192, 1995.
7. 2, FP, or TP prostanoid-receptor stimulation may reduce intraocular pressure. Invest. Ophthalmol. Vis. Sci., 31:2560-2567, 1990.
8. Protzman, C.E. and Woodward, D.F. Prostanoid-induced blood aqueous barrier breakdown in rabbits involves the EP receptor subtype. Invest. Ophthalmol. Vis. Sci., 31:2463-2466, 1990.
9. 2 receptor is the predominant prostanoid-receptor in the human ciliary muscle. Br. J. Ophthalmol., 77:110-114, 1993.
10. 2-receptor stimulated cyclic AMP synthesis in cultured human non-pigmented ciliary epithelium. Exp. Eye Res., 58:563-566, 1994.
11. Zhao, C., Fujimoto, N. and Shichi, H. Immunocytochemical localization of prostaglandin E2 receptor subtypes in porcine ocular tissues. I. Uveal tissues. J. Ocul. Pharmacol. Ther., 11:421-435, 1995.
12. Schaad, N.C., Magistretti, P.J. and Schorderet, M. Prostanoids and their role in cell-cell interactions in the central nervous system. Neurochem. Int., 18:303-322, 1991.
13. Bhatacherjee, P., Rhodes, L. and Paterson, C.A. Prostaglandin receptors coupled to adenylyl cyclase in the iris-ciliary body of rabbits, cats and cows. Exp. Eye Res., 56:327-333, 1993.
14. 4-antagonist, AH22921. Adv. Prostaglandin Thromboxane Leukot. Res., 23:241-246, 1995.
15. Ohia, S.E., Opere, C., Tang, L. and Al-zadjali, K. Role of cyclic AMP in prostaglandin mediated responses in the neural retina. J. Ocul. Pharmacol. Ther., 11:73-81, 1995.
16. Camras, C.B., Bito, L.Z. and Eakins, K.E. Reduction of intraocular pressure by prostaglandins applied topically to the eyes of conscious rabbits. Invest. Ophthalmol. Vis. Sci., 16:1125-1134, 1977.
17. Camras, C.B. Prostaglandins. In: The Glaucoma, 2nd Edition, Ritch, R., Shields, M.B. and Krupin, T., eds. Mosby-Year Book, Inc., 1996, p. 1449-1461.
18. 2α increases uveoscleral outflow in cynomolgus monkey. Exp. Eye Res., 49:389-402, 1989.
19. 2α-1-isopropyl ester in cynomolgus monkey. Exp Eye Res., 48:707-716, 1989.
20. 2α analogue, on aqueous humor dynamics in human eyes. Ophthalmology 100:1297-1304, 1993.
21. Sears, M.L. Regulation of aqueous flow by the adenylate cyclase receptor complex in the ciliary epithelium. Am. J. Ophthalmol., 100:194-198, 1985.
22. Kaufman, P.L. Adenosine 3′,5′-cyclic-monophosphate and outflow facility in monkey eyes with intact and retrodisplaced ciliary muscle. Exp. Eye Res., 44:415-423, 1987.
23. Erickson, K., Liang, L., Shum, P. and Nathanson, J.A. Adrenergic regulation of aqueous outflow. J. Ocular Pharmacol., 10:241-252, 1994.
24. Zhan, G-L., Ohia, S., Camras, C.B., Opere, C. and Tang, L. Effects of prostaglandins on cyclic AMP formation in cultured human ciliary muscle cells. Invest. Ophthalmol. Vis. Sci., 35(suppl):1887, 1994.
25. Tamm, E., Frugel, C., Baur, A. and Lutjen-Drecoll E. Cell cultures of human ciliary muscle: growth, ultrastructural and immunocytochemical characteristics. Exp. Eye Res., 53:375-387, 1991.
26. Woldemussie, E., Feldmann, B.J. and Chen, J. Characterization of muscarinic receptors in cultured human iris sphincter and ciliray muscle cells. Exp. Eye Res., 56:385-392, 1993.
27. Campell, G.R., Chanley, J.H. and Burnstock, G. Development of smooth muscle cells in tissue culture. J. Anat. 117(2):295-312, 1974.
28. 2α on porcine ciliary smooth muscle cells in culture. Curr. Eye Res., 14:1155-1163, 1995.
29. Dong, Y.J., Jones, R.L. and Wilson, N.H. Prostaglandin E receptor subtypes in smooth muscle: Agonist activities of stable prostacyclin analogues. Br. J. Pharmacol., 87:97-107, 1986.
30. Eglen, R.M. and Whiting, R.L. Characterization of the prostanoid receptor profile of enprostil and isomers in smooth muscle and platelets in vitro. Br. J. Pharmacol., 98:1335-1343, 1989.
31. Coleman, R.A., Kennedy, I., Humphrey, P.P.A., Bunce, K. and Lumley, P. Prostanoids and their receptors. In Comprehensive Medicinal Chemistry: The Rational Design, Mechanistic Study and Therapeutic Application of Chemical Compounds, Hansch, C., Sammes, P.G. and Taylor, J.B., eds. Pergamon Press, New York, 1990, p. 643-714.
32. Coleman, R.A., Smith, W.L. and Narumiya, S. Classification of prostanoid-receptors: properties, distribution, and structure of the receptors and their subtype. Pharmacol. Rev., 46:205-209, 1994.
33. 2 analogues on adenylate cyclic in rabbit iris-ciliary body membrane fraction. Exp. Eye Res., 51:585-590, 1990.
34. 2 by bovine cultured airway smooth muscle cells: regulation by cAMP. J. Appl. Physiol., 78:623-628, 1995.
35. 2α effects on isolated rhesus monkey ciliary muscle. Invest. Ophthalmol. Vis. Sci., 36:2461-2465, 1995.
36. 2α and its analogs induce release of endogenous prostaglandins in iris and ciliary muscles isolated from cat and other mammalian species. Exp. Eye Res., 63:305-310, 1996.