Postmenopausal hormone replacement: Effects on autonomic, neuroendocrine, and immune reactivity to brief psychological stressors

Psychosomatic Medicine

Volumn 60, Issue 1, 1998, Pages 17-25

  Burleson, Mary H ^a   Malarkey, William B ^a,b,d   Cacioppo, John T ^a,c   Poehlmann, Kirsten M ^c   Kiecolt Glaser, Janice K ^a   Berntson, Gary G ^c   Glaser, Ronald ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^d THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

Author keywords

Cardiovascular reactivity; Cellular immune response; Estrogen; Postmenopausal hormone replacement; Psychological stress; Respiratory sinus arrhythmia

Indexed keywords

ADRENALIN; CATECHOLAMINE; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CONCANAVALIN A; CONJUGATED ESTROGEN; CORTICOTROPIN; ESTROGEN; GESTAGEN; HYDROCORTISONE; LYMPHOCYTE ANTIGEN; MEDROXYPROGESTERONE ACETATE; MITOGENIC AGENT; NORADRENALIN; PHYTOHEMAGGLUTININ;

ADULT; AGED; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BREATHING RATE; CELLULAR IMMUNITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ESTROGEN THERAPY; FEMALE; HEART RATE; HUMAN; LONG TERM CARE; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE TRANSFORMATION; MAJOR CLINICAL STUDY; MENTAL STRESS; NATURAL KILLER CELL; NEUROENDOCRINE SYSTEM; POSTMENOPAUSE; PRIORITY JOURNAL; SINUS ARRHYTHMIA; SPEECH; T LYMPHOCYTE SUBPOPULATION; TASK PERFORMANCE;

EID: 0031891893     PISSN: 00333174     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006842-199801000-00004     Document Type: Article

References (45)

1. Lindheim SR, Legro RS, Bernstein L, et al: Behavioral stress responses in premenopausal and postmenopausal women and the effects of estrogen. Am J Obstet Gynecol 167:1831-1836, 1992
2. Owens JF, Stoney CM, Matthews KA: Menopausal status influences ambulatory blood pressure levels and blood pressure changes during mental stress. Circulation 88:2794-2802, 1993
3. Saab PG, Matthews KA, Stoney CM, et al: Premenopausal and postmenopausal women differ in their cardiovascular and neuroendocrine responses to behavioral stressors. Psychophysiology 26:270-280, 1989
4. Del Rio G, Velardo A, Zizzo G, et al: Effect of estradiol on the sympathoadrenal response to mental stress in normal men. J Clin Endocrinol Metab 79:836-840, 1994
5. Krantz DS, Manuck SB: Acute psychophysiologic reactivity and risk of cardiovascular disease: A review and methodologic critique. Psychol Bull 96:435-464, 1984
6. Fredrikson M, Matthews KA: Cardiovascular responses to behavioral stress and hypertension: A meta-analytic review. Ann Behav Med 12:30-39, 1990
7. Backstrom T: Estrogen and progesterone in relation to different activities in the central nervous system. Acta Obstet Gynaecol Scand 66:1-17, 1977
8. Klaiber EL, Kobayashi Y, Broverman DM, et al: Plasma monoamine oxidase activity in regularly menstruating women and in amenorrheic women receiving cyclic treatment with estrogens and a progestin. J Clin Endocrinol 33:630-638, 1971
9. PEPI Trial Writing Group: Effects of estrogen or estrogen/ progestin regimens on heart disease risk factors in postmenopausal women: The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. JAMA 273:199-208, 1995
10. Ansar Ahmed S, Penhale WJ, Talal N: Sex hormones, immune responses and autoimmune diseases. Am J Pathol 121:531-551, 1985
11. Grossman CJ: Possible underlying mechanisms of sexual dimorphism in the immune response, fact and hypothesis. J Steroid Biochem 34:241-251, 1989
12. McCruden AG, Stimson WH: Sex hormones and immune function. In Ader R, Felten DL, Cohen N (eds), Psychoneuroimmunology, 2nd Edition. San Diego, CA, Academic Press, 1991, 475-493
13. Grossman CJ: Interactions between the gonadal steroids and the immune system. Science 227:257-261, 1985
14. Pacifici R, Brown C, Puscheck E, et al: Effect of surgical menopause and estrogen replacement on cytokine release from human blood mononuclear cells. Proc Nat Acad Sci 88:5134-5138, 1991
15. Paavonen T, Andersson LC, Adlercreutz H: Sex hormone regulation of in vitro immune response: Estradiol enhances human B cell maturation via inhibition of suppressor T cells in pokeweed mitogen-stimulated cultures. J Exp Med 154:1935-1945, 1981
16. Cohen JH, Daniel L, Cordier G, et al: Sex steroid receptors in peripheral T cells: Absence of androgen receptors and restriction of estrogen receptors to OKT8-positive cells. J Immunol 131: 2767-2771, 1983
17. Clemens LE, Sitteri PK, Stites DP: Mechanisms of immunosuppression of progesterone on maternal lymphocyte activation during pregnancy. J Immunol 122:127-132, 1979
18. Skinnider LF, Laxdal V: The effect of progesterone, oestrogens, and hydrocortisones on the mitogenic response of lymphocytes to phytohaemagglutinin in pregnant and nonpregnant women. Br J Obstet Gynaecol 88:1110-1117, 1981
19. Berntson GG, Cacioppo JT, Quigley KS: Respiratory sinus arrhythmia: Autonomic origins, physiological mechanisms, and psychophysiological implications. Psychophysiology 30:183-196, 1993
20. Berntson GG, Cacioppo JT, Binkley PF, et al: Autonomic cardiac control. III. Psychological stress and cardiac response in autonomic space as revealed by pharmacological blockades. Psychophysiology 31:599-608, 1994
21. Cacioppo JT, Malarkey WB, Kiecolt-Glaser JK, et al: Heterogeneity in neuroendocrine and immune responses to brief psychological stressors as a function of autonomic cardiac activation. Psychosom Med 57:154-164, 1995
22. Berntson GG, Quigley KS, Jang J, et al: A conceptual approach to artifact identification: Application to heart period data. Psychophysiology 27:568-598, 1990
23. Kiecolt-Glaser JK, Dura JR, Speicher CE, et al: Spousal care-givers of dementia victims: Longitudinal changes in immunity and health. Psychosom Med 49:13-34, 1991
24. Glaser R, Rice J, Speicher CE, et al: Stress depresses interferon production by leukocytes and natural killer cell activity in humans. Behav Neurosci 100:675-678, 1986
25. Kazimer RM, Whisler RL, Stephens RE, et al: Sensitivity of glioma and fetal brain cell lines to natural killer cytolysis in a monolayer assay. J Neurooncol 7:145-150, 1989
26. Blumenthal JA, Fredrikson M, Matthews KA, et al: Stress reactivity and exercise training in premenopausal and postmenopausal women. Health Psychol 10:384-391, 1991
27. Kiecolt-Glaser JK, Cacioppo JT, Malarkey WB, et al: Acute psychological stressors and short-term immune changes: What, why, for whom, and to what extent? Psychosom Med 54:680-685, 1992
28. Sgoutas-Emch SA, Cacioppo JT, Uchino BN, et al: The effects of an acute psychological stressor on cardiovascular, endocrine, and cellular immune response: A prospective study of individuals high and low in heart rate reactivity. Psychophysiology 31:264-271, 1993
29. Caggiula AR, McAllister CG, Matthews KA, et al: Psychological stress and immunological responsiveness in normally cycling, follicular-stage women. J Neuroimmunol 59:103-111, 1995
30. Herbert TB, Cohen S, Marsland AL, et al: Cardiovascular reactivity and the course of immune response to an acute psychological stressor. Psychosom Med 56:337-344, 1994
31. Sapolsky RM: The effects of stress upon hippocampal function. In Brown M, Rivier K, Koob G (eds), The Neurobiology and Neuroendocrinology of Stress. New York, Plenum, 1991
32. Manuck SB, Cohen S, Rabin BS, et al: Individual differences in cellular immune response to stress. Psychol Sci 2:111-115, 1991
33. Hrushesky WJM, Fader DJ, Schmitt O, et al: The respiratory sinus arrhythmia: A measure of cardiac age. Science 224:1001-1004, 1984
34. Saul JP, Cohen RJ: Respiratory sinus arrhythmia. In Levy MN, Schwartz PJ (eds), Vagal Control of the Heart: Experimental Basis and Clinical Implications. Armonk, NY, Futura Publishing Co Inc, 1994, 511-536
35. Johnson AK, Anderson EA: Stress and arousal. In Cacioppo JT, Tassinary LG (eds), Principles of Psychophysiology: Physical, Social and Inferential Elements. New York, Cambridge University Press, 1990, 216-252
36. Schedlowski M, Falk A, Rohne A, et al: Catecholamines induce alterations of distribution and activity of human natural killer (NK) cells. J Clin Immunol 13:344-351, 1993
37. Sanchez-Guerrero J, Liang MH, Karlson EW, et al: Postmenopausal estrogen therapy and the risk for developing systemic lupus erythematosus. Ann Intern Med 122:430-433, 1995
38. Malarkey WB, Pearl DK, Demers LM, et al: The influence of academic stress and season on 24-hour mean concentrations of ACTH, cortisol, and β-endorphin. Psychoneuroendocrinology 20:499-508, 1995
39. Sapolsky RM: Neuroendocrinology of the stress-response. In Becker JB, Breedlove SM, Crews D (eds), Behavioral Endocrinology. Cambridge, MA, The MIT Press, 1992, 287-324
40. Lieberman S: Are the differences between estradiol and other estrogens, naturally occurring or synthetic, merely semantical? J Clin Endocrinol Metab 81:850-851, 1996
41. Kelly JJ, Rajkovic IA, O'Sullivan AJ, et al: Effects of different oral oestrogen formulations on insulin-like growth factor-I, growth hormone, and growth hormone binding protein in post-menopausal women. Clin Endocrinol 39:561-567, 1993
42. Maschak CA, Lobo R, Dozono TR, et al: Comparison of pharmacodynamic properties of various estrogen formulations. Am J Obstet Gynecol 144:511-518, 1982
43. Nachtigall LE: Emerging delivery systems for estrogen replacement: Aspects of transdermal and oral delivery. Am J Obstet Gynecol 173:993-997, 1995
44. O'Sullivan AJ, Ho KKY: A comparison of the effects of oral and transdermal estrogen replacement on insulin sensitivity in post-menopausal women. J Clin Endocrinol Metab 80:1783-1788, 1995
45. Weissberger AJ, Ho KKY, Lazarus L: Contrasting effects of oral and transdermal routes of estrogen replacement therapy on 24-hour growth hormone (GH) secretion, insulin-like growth factor I, and GH-binding protein in postmenopausal women. J Clin Endocrinol Metab 72:374-381, 1991