Cytotoxic strains of Pseudomonas aeruginosa can damage the intact corneal surface in vitro

CLAO Journal

Volumn 24, Issue 1, 1998, Pages 41-47

  Fleiszig, Suzanne M J ^a   Lee, Ellen J ^a   Wu, Christine ^a   Andika, Renisa C ^a   Vallas, Vicky ^a   Portoles, Marta ^a   Frank, Dara W ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BACTERIUM ADHERENCE; CONTROLLED STUDY; CORNEA EPITHELIUM; CORNEA INJURY; CYTOTOXICITY; KERATITIS; NONHUMAN; PSEUDOMONAS AERUGINOSA; RABBIT; RAT; SOFT CONTACT LENS;

ANIMALS; BACTERIAL PROTEINS; CELL DEATH; DNA-BINDING PROTEINS; EPITHELIUM, CORNEAL; EYE INFECTIONS, BACTERIAL; GENES, BACTERIAL; HUMANS; KERATITIS; MICROSCOPY, ELECTRON, SCANNING; ORGAN CULTURE TECHNIQUES; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; TRANS-ACTIVATORS;

EID: 0031891691     PISSN: 07338902     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Alfonso E, Mandelbaum S, Fox MJ, et al: Ulcerative keratitis associated with contact lens wear. Am J Ophthalmol 1986;101:429-433.
2. Dunn JP, Mondino BJ, Weissman BA, et al: Corneal ulcers associated with disposable hydrogel lenses Am J Ophthalmol 1989;108:113-117
3. Bruce AS, Brennan NA: Corneal pathophysiology with contact lens wear. Surv Ophthalmol 1990;35:25-58.
4. Imayasu M, Pettroll WM, Jester JV, et al: The relationship between contact lens oxygen transmissibility and binding of Pseudomonas aeruginosa to the cornea after overnight wear Ophthalmology 1994;101:371-388.
5. Ramphal R, McNiece MT, Polack FD: Adherence of Pseudomonas aeruginosa to the injured cornea. A step in the pathogenesis of corneal infections. Ann Ophthalmol 1981;100:1956-1958.
6. Fleiszig SMJ, Zaidi TS, Preston MJ, et al: The relationship between cytotoxicity and epithelial cell invasion by corneal isolates of Pseudomonas aeruginosa. Infect Immun 1996;64:2288-2294.
7. Fleiszig SMJ, Zaidi TS, Fletcher EL, et al: Pseudomonas aeruginosa invades corneal epithelial cells during experimental infection. Infect Immun 1994;62:3485-3492.
8. Fleiszig SMJ, Zaidi TS, Pier GB: Pseudomonas aeruginosa survival and multiplication within corneal epithelial cells in vitro. Infect Immun 1995;63:4072-4077.
9. Apodaca G, Bomsel M, Lindstedt R, et al: Characterization of Pseudomonas aeruginosa induced MDCK cell injury: glycosylation-defective host cells are resistant to bacterial killing. Infect Immun 1995;63:1541-1551.
10. Fleiszig SMJ, Wiener-Kronish JP, Miyazaki H, et al: Pseudomonas aeruginosa-mediated cytotoxicity and invasion correlate to distinct genotypes at the loci encoding exoenzyme S. Infect Immun 1997;65:579-586.
11. Frank DW, Nair G, Schweizer HP: Construction and characterization of chromosomal insertional mutants of the Pseudomonas aeruginosa exoenzyme S trains-regulatory locus. Infect Immun 1994;62:554-563.
12. Fleiszig SMJ, Efron N, Pier GB: Extended wear enhances Pseudomonas aeruginosa adherence to human corneal epithelium. Invest Ophthalmol Vis Sci 1992;33:2908-2916.
13. Fleiszig SMJ, Zaidi TS, Ramphal R, et al: Modulation of P. aeruginosa adherence to the corneal surface by mucus. Infect Immun 1994;62:1799-1805.
14. Kudoh I, Wiener-Kronish JP, Hashimoto S, et al: Exoproduct secretions of Pseudomonas aeruginosa strains influence severity of alveolar epithelial injury. Am J Physiol 1994;267:L551-L556.
15. Fleiszig SMJ, Fletcher EL, Pier GB: Evidence that pre-cellular factors may be involved in the non-specific inhibition of bacterial adherence to intact cornea. (Abstract). Invest Ophthalmol Vis Sci 1992;33(Suppl.):1167.
16. Fleiszig SMJ, Zaidi TS, Pier GB: Ocular mucus and Pseudomonas aeruginosa adherence. Adv Exp Med Biol 1994;350:359-362.
17. Fleiszig SMJ, Evans DJ, Do N, et al: Epithelial cell polarity affects Pseudomonas aeruginosa invasion and cytotoxicity. Infect Immun 1997;65:2861-2867.
18. Smith JJ, Travis SM, Greenberg EP, et al: Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid. Cell 1996;85:229-236.
19. Yahr T L, Goranson J, Frank DW: Exoenzyme S of Pseudomonas aeruginosa is secreted by a type III pathway Mol Microbiol 1996;22:991-1003.
20. Gilbert P, Evans DJ, Brown MRW: Formation and dispersal of bacterial biofilms in vivo and in situ. J Appl Bacteriol 1993;74:675-785.
21. Fletcher EL, Fleiszig SMJ, Brennan NA: Lipopolysaccharide in adherence of P. aeruginosa to cornea and contact lenses. Invest Ophthalmol Vis Sci 1993;34:1930-1936.
22. Fletcher EL, Weissman BA, Efron N, et al: The role of pili in the attachment of Pseudomonas aeruginosa to unworn hydrogel contact lenses. Curr Eye Res 1993;12:1067-1071.
23. Fleiszig SMJ, Efron N: Microbial flora in current and former contact lens wearers. J Clin Microbiol 1992;30:1156-1161.