Opioid inhibition of adenylyl cyclase in membranes from pertussis toxin- related NG108-15 cells

Journal of Receptor and Signal Transduction Research

Volumn 18, Issue 1, 1998, Pages 25-49

  Selley, Dana E ^a   Breivogel, Christopher S ^a   Childers, Steven R ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; DELTA OPIATE RECEPTOR ANTAGONIST; ENZYME INHIBITOR; GUANINE NUCLEOTIDE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE TRIPHOSPHATASE; GUANYLYLIMIDODIPHOSPHATE; NALTRINDOLE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PERTUSSIS TOXIN; PHOSPHORUS 32; PROSTAGLANDIN E1; SULFUR 35;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ABUSE; DRUG RECEPTOR BINDING; ENZYME ASSAY; ENZYME INHIBITION; HYDROLYSIS; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; OPIATE ADDICTION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0031891582     PISSN: 10799893     EISSN: None     Source Type: Journal    
DOI: 10.3109/10799899809039163     Document Type: Article

References (50)

1. Bergsbaken, C.L.; Sommers, S.L.; and Law, P.Y. Effect of forskolin and isobutylmethylxanthine on Delta-opioid receptor activity in neuroblastoma x glioma NG108-15 cells, J. Pharmacol. Exp. Ther. 264, 1474-1483, 1993.
2. Birnbaumer, L.; Yatani, A.; Vandongen, A.M.J.; Graf, R.; Codina, J.; Okabe, K.; Mattera, R.; and Brown, A.M. G protein coupling of receptors to ionic channels and other effector systems, British Journal of Clinical Pharmacology 30, 13S-22S, 1990.
3. Bradford, M.M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem. 72, 248-254, 1976.
4. Burns, D.L.; Hewlett, E.L.; Moss, J.; and Vaughan, M. Pertussis toxin inhibits enkephalin stimulation of GTPase of NG108-15 cells., J. Biol. Chem. 258, 1435-1438, 1983.
5. z, a guanine nucleotide-binding with unique biochemical properties, J. Biol. Chem. 265, 2383-2390, 1990.
6. Chang, K.-J.; and Cuatrecasas, P. Multiple opiate receptors: Enkephalins and morphine bind to receptors of different specificity, J. Biol. Chem. 254, 2610-2618, 1979.
7. s-stimulated adenylate cyclase, J. Neurochem. 50, 543-553, 1988.
8. Costa, T.; Klinz, F.-J.; Vachon, L.; and Herz, A. Opioid receptors are coupled tightly to G proteins but loosely to adenylate cyclase in NG108-15 cell membranes, Mol. Pharmacol. 34, 744-754, 1988.
9. Costa, T.; Lang, J.; Gless, C.; and Herz, A. Spontaneous association between opioid receptors and GTP-binding proteins in native membranes: specific regulation by antagonists and sodium ions, Mol. Pharmacol. 37, 383-394, 1990.
10. Evans, C.J.; Keith Jr., D.E.; Morrison, H.; Magendzo, K.; and Edwards, R.H. Cloning of a delta opioid receptor by functional expression, Science 258, 1952-1955, 1992.
11. Fawzi, A.B.; Fay, D.S.; Murphy, E.A.; Tamir, H.; Erdos, J.J.; and Northup, J.K. Rhodopsin and the retinal G-protein distinguish among G-protein βγ subunit forms, J. Biol. Chem. 266, 12194-12200, 1991.
12. o in reconstituted phospholipid vesicles, J. Biol. Chem. 264, 3909-3915, 1989.
13. Fung, B.K.-K. Characterization of transducin from bovine retinal rod outer segments: I. Separation and reconstitution of the subunits, J. Biol. Chem. 258, 10495-10502, 1983.
14. Hilf, G.; Gierschik, P.; and Jakobs, K.H. Muscarinic acetylcholine receptor-stimulated binding of guanosine 5′-O-(3-thiotriphosphate) to guanine-nucleotide-binding proteins in cardiac membranes, Eur. J. Biochem. 186, 725-731, 1989.
15. Hsia, J.A.; Moss, J.; Hewlett, E.L.; and Vaughan, M. ADP-ribosylation of adenylate cyclase by pertussis toxin: Effects on inhibitory agonist binding, J. Biol. Chem. 259, 1086-1090, 1984.
16. Huff, R.M.; and Neer, E.J. Subunit interactions of native and ADP-ribosylated α39 and α41, two guanine nucleotide-binding proteins from bovine cerebral cortex, J. Biol. Chem. 261, 1105-1110, 1986.
17. Katada, T.; Oinuma, M.; and Ui, M. Mechanisms for inhibition of the catalytic activity of adenylate cyclase by the guanine nucleotide-binding proteins serving as the substrate of islet-activating protein, pertussis toxin, J. Biol. Chem. 261, 5215-5221, 1986.
18. Kieffer, B.L.; Befort, K.; Gaveriaux-Ruff, C.; and Hirth, C.G. The 6-opioid receptor: Isolation of a cDNA by expression cloning and pharmacological characterization, Proc. Natl. Acad. Sci. USA 89, 12048-12052, 1992.
19. Kikkawa, S.; Takahashi, K.; Takahashi, K.-i.; Shimada, N.; Ui, M.; Kimura, N.; and Katada, T. Conversion of GDP into GTP by nucleoside diphosphate kinase on the GTP-binding proteins, J. Biol. Chem. 265, 21536-21540, 1990.
20. z, J. Biol. Chem. 270, 1734-1741, 1995.
21. Kurose, H.; Katada, T.; Amano, T.; and Ui, M. Specific uncoupling by islet-activating, pertussis toxin, of negative signal transduction via α-adrenergic, cholinergic, and opiate receptors in neuroblastoma x glioma hybrid cells., J. Biol. Chem. 258, 4870-4875, 1983.
22. z coupling to the rat κ-opioid receptor, FEBS Letts. 360, 97-99, 1995.
23. Law, P.Y.; Horn, D.S.; and Loh, H.H. Opiate receptor down-regulation and desensitization in neuroblastoma x glioma NG108-15 hybrid cells are two separate cellular adaptation processes, Mol. Pharmacol. 24, 413-424, 1983.
24. Law, P.Y.; Louie, A.K.; and Loh, H.H. Effect of pertussis toxin treatment on the down-regulation of opiate receptors in neuroblastoma x glioma NG108-15 hybrid cells, J. Biol. Chem. 260, 14818-14823, 1985.
25. sα highlights the requirement for dissociation of G protein subunits, J. Biol. Chem. 267, 1212-1218, 1992.
26. 35S]thio)triphosphate binding, Mol. Pharmacol. 44, 115-123, 1993.
27. i2, Biochem. J. 267, 391-398, 1990.
28. Moss, J.; Tsai, S.-C.; Bruni, P.; Adamik, R.; Kanaho, Y.; Hewlett, E.L.; and Vaughan, M. Pertussis toxin-catalyzed ADP-ribosylation of adenylate cyclase: effects of guanyl nucleotides and rhodopsin, Developements in Biological Standardization 61, 34-49, 1985.
29. Neer, E.J.; Lok, J.M.; and Wolf, L.G. Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase, J. Biol. Chem. 259, 14222-14229, 1984.
30. z?, Molecular and Cellular Endocrinology 100, 71-74, 1994.
31. + channels, J. Biol. Chem. 265, 12854-12858, 1990.
32. Onaran, H.O.; Costa, T.; and Rodbard, D. βγ Subunits of guanine nucleotide-binding proteins and regulation of spontaneous receptor activity: Thermodynamic model for the interaction between receptors and guanine nucleotide-binding protein subunits, Mol. Pharmacol. 43, 245-256, 1993.
33. Ott, S.; Costa, T.; and Herz, A. Sodium modulates opioid receptors through a membrane component different from G-proteins, J. Biol. Chem. 263, 10524-10533, 1988.
34. Parker, E.M.; Kameyama, K.; Higashijima, T.; and Ross, E.M. Reconstitutively active G protein-coupled receptors purified from baculovirus-infected insect cells, J. Biol. Chem. 266, 519-527, 1991.
35. Polastron, J.; Jauzac, P.; and Meunier, J.-C. The δ-opioid receptor in neuroblastoma X glioma NG108-15 hybrid cells is strongly precoupled to a G-protein, Eur. J. Pharmacol. 226, 133-139, 1992.
36. Premont, R.T.; Inglese, J.; and Lefkowitz, R.J. Protein kinases that phosphorylate activated G protein-coupled receptors, FASEB Journal 9, 175-182, 1995.
37. Randazzo, P.A.; Northup, J.K.; and Kahn, R.A. Regulatory GTP-binding proteins (ADP-ribosylation factor, Gt, and RAS) are not activated directly by nucleoside diphosphate kinase, J. Biol. Chem. 267, 18182-18189, 1992.
38. Salomon, Y. Adenylate cyclase assay, Advances in Cyclic Nucleotide Research 10, 35-55, 1979.
39. m GTPase studies, J. Pharmacol. Exp. Ther. 263, 99-104, 1992.
40. Selley, D.E.; Breivogel, C.S.; and Childers, S.R. Modification of opioid receptor-G-protein function by low pH pretreatment of membranes from NG108-15 cells: Increase in opioid agonist efficacy by decreased inactivation of G-proteins, Mol. Pharmacol. 44, 731-741, 1993.
41. 35S]GTPγS binding in rat thalamus and cultured cell lines: Signal transduction mechanisms underlying agonist efficacy, Mol. Pharmacol. 51, 87-96, 1997.
42. Sharma, S.K.; Nirenberg, M.; and Klee, W.A. Morphine receptors as regulators of adenylate cyclase activity, Proc. Natl. Acad. Sci. USA 72, 590-594, 1975.
43. z proteins, Biochemical and Biophysical Research Communications 208, 223-229, 1995.
44. 13, J. Biol. Chem. 269, 19796-19802, 1994.
45. 13 α-subunits are immunochemically detectable in most membranes of various mammalian cells and tissues, Biochemical and Biophysical Research Communications 198, 906-914, 1994.
46. i proteins: Effects of pertussis toxin, Molecular Endocrinology 3, 1115-1124, 1989.
47. 35S]thio)triphosphate binding to membranes from human neuroblastoma SH-SY5Y cells, Mol. Pharmacol. 47, 848-854, 1995.
48. Vachon, L.; Costa, T.; and Herz, A. GTPase and adenylate cyclase desensitize at different rates in NG108-15 cells, Mol. Pharmacol. 31, 159-168, 1987.
49. West, R.E.; Moss, J.; Vaughan, M.; Liu, T.; and Liu, T.-Y. Pertussis toxin-catalyzed ADP-ribosylation of transducin, J. Biol. Chem. 260, 14428-14430, 1985.
50. z-Mediated hormonal inhibition of cyclic AMP accumulation, Science 255, 339-342, 1992.