Construction of a model of the Candida albicans lanosterol 14-α- demethylase active site using the homology modelling technique

Pharmaceutica Acta Helvetiae

Volumn 72, Issue 5, 1998, Pages 271-277

  Höltje, Hans Dieter ^a   Fattorusso, Caterina ^b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF SALERNO   (Italy)

Author keywords

CVFF; Cytochrome P450 model; Homology modelling; Lanosterol 14 demethylase; Molecular dynamics

Indexed keywords

CYTOCHROME P450 ISOENZYME; STEROL 14ALPHA DEMETHYLASE; UNCLASSIFIED DRUG;

ARTICLE; CANDIDA ALBICANS; ENZYME ACTIVE SITE; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; STEROL METABOLISM;

BINDING SITES; CANDIDA ALBICANS; CYTOCHROME P-450 ENZYME SYSTEM; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OXIDOREDUCTASES; PROTEIN STRUCTURE, SECONDARY; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0031891490     PISSN: 00316865     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-6865(97)00036-8     Document Type: Article

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