Mutual inhibition between quinine and etoposide by human liver microsomes: Evidence for cytochrome P4503A4 involvement in their major metabolic pathways

Drug Metabolism and Disposition

Volumn 26, Issue 2, 1998, Pages 188-191

  Zhao, Xue Jun ^b   Kawashiro, Takashi ^b   Ishizaki, Takashi ^a  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ETOPOSIDE; KETOCONAZOLE; QUININE; TROLEANDOMYCIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CATALYSIS; DRUG DETERMINATION; DRUG ELIMINATION; DRUG INHIBITION; DRUG METABOLISM; ENZYME SPECIFICITY; HEART ARRHYTHMIA; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROXYLATION; HYPOGLYCEMIA; LEG CRAMP; LEUKOPENIA; LIVER METABOLISM; LIVER MICROSOME; MALARIA; PRIORITY JOURNAL;

CYTOCHROME P-450 ENZYME SYSTEM; ETOPOSIDE; HUMANS; KETOCONAZOLE; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; OXIDOREDUCTASES, O-DEMETHYLATING; QUINIDINE; QUININE; TROLEANDOMYCIN;

CINCHONA PUBESCENS;

EID: 0031891442     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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