Robot-aided functional imaging: Application to a motor learning study

Human Brain Mapping

Volumn 6, Issue 1, 1998, Pages 59-72

  Krebs, Hermano I ^a,b,e   Brashers Krug, Thomas ^b   Rauch, Scott L ^c   Savage, Cary R ^c   Hogan, Neville ^a,b   Rubin, Robert H ^b,c,d   Fischman, Alan J ^b,c   Alpert, Nathaniel M ^c  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^e NONE   (United States)

Author keywords

Arm movement; Functional imaging; Motor learning; Robot aided

Indexed keywords

ADULT; ARM MOVEMENT; ARTICLE; BRAIN; CEREBELLUM CORTEX; CONTROLLED STUDY; HUMAN; HUMAN EXPERIMENT; IMAGING; LEARNING; MALE; MOTOR ACTIVITY; NERVE CONDUCTION; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; ROBOTICS; STRIATE CORTEX;

ADULT; BRAIN MAPPING; HUMANS; LEARNING; MALE; PSYCHOMOTOR PERFORMANCE; REFERENCE VALUES; ROBOTICS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0031890919     PISSN: 10659471     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0193(1998)6:1<59::AID-HBM5>3.0.CO;2-K     Document Type: Article

References (28)

1. Aisen ML, Krebs HI, McDowell F, Hogan N, Volpe BT (1997): The effect of robot assisted therapy and rehabilitative training on motor recovery following stroke. Arch Neurol 54:443-446.
2. Alpert NM, Berdichevsky D, Weise S, Tang J, Rauch SL (1993): Stereotatic transformation of PET scans by nonlinear least squares. In: Uemura K, Lassen NA, Jones T, Kanno I (eds): Quantification of Brain Function: Tracer Kinetics and Image Analysis in Brain PET, Amsterdam Elsevier pp 459-463.
3. Berns GS, Cohen JD, Mintun MA (1997): Brain regions responsive to novelty in the absence of awareness Science 276:1272-1275.
4. Brashers-Krug T, Shadmehr R, Bizzi E (1996): Consolidation in human motor memory. Nature 382:252-255.
5. Doyon J, Owen AM, Petrides M (1996): Functional anatomy of visuomotor skill learning in human subjects examined with positron emission tomography. Eur J Neurosci 8:637-648.
6. Friston K, Frith C, Liddle P, Frackowiak R (1991): Comparing functional (PET) images: The assessment of significant change. J Cereb Blood Flow Metab 11:690-699.
7. Georgopoulos AP, Kalaska JF, Crutcher MD, Caminiti R, Massey JT (1984): The representation of movement direction in the motor cortex: Single cell and population studies. In: Dynamic Aspects of Neocortical Function, New York: John Wiley & Sons.
8. Grafton ST, Woods RP, Tyszka M (1994): Functional imaging of procedural motor learning: Relating cerebral blood flow with individual subject performance. Hum Brain Mapping 1:221-234.
9. Grafton ST, Hazeltine E, Ivri R (1995): Functional mapping of sequence learning in normal humans. J Cogn Neurosci 7:497-510.
10. Graybiel AM (1995): Building action repertoires: Memory and learning functions of the basal ganglia. Curr Opin Neurobiol 5:733-741.
11. Hogan N, Krebs HI, Sharon A, Charnnarong J (1995): Interactive Robotic Therapist. U.S. Patent Number 5,466,213 MIT.
12. Kalaska JF, Cohen DA, Hyde ML, Prud'homme M (1989): A comparison of movement direction-related versus load direction-related activity in primate motor cortex using a two-dimensional reaching task. J Neurosci 9:2080-2102.
13. Kops ER, Herzog H, Schmidt A, Holte S, Feinendegen LE (1990): Performance characteristics of an eight-ring whole body PET scanner. J Comput Assist Tomogr 14:437-145.
14. Kosslyn SM, Alpert NM, Thompson WL, Chabris CF, Rauch SL, Anderson AK (1994): Identifying objects seen from canonical and noncanonical viewpoints: A PET investigation. Brain 117:1055-1071.
15. Krebs HI, Brashers-Krug T, Rauch SL, Savage CR, Hogan N, Rubin RH, Fischmann AJ, Alpert NM (1995): Robot-aided functional imaging. In: Proceedings of the second symposium on Medical Robotics and Computer Assisted Surgery, Baltimore: Wiley-Liss pp 296-299.
16. Krebs HI, Aisen ML, Volpe BT, Hogan N (1996): Pilot clinical trial of a robot-aided neuro-rehabilitation workstation with stroke patients. In: Proceedings of the Telemanipulator and Telepresence Technologies III. SPIE - The International Society for Optical Engineering, vol. 2901.
17. Krebs HI (1997): Robot-aided neuro-rehabilitation and functional imaging Ph.D. Thesis, Massachusetts Institute of Technology.
18. Mesulam M-M (1985): Principles of Behavioral Neurology, Philadelphia: F.A. Davis Company.
19. Mitz AR, Godschalk M, Wise SP (1991): Learning-dependent neuronal activity in the premotor cortex: Activity during the acquisition of conditional motor associations. J Neurosci 11:1855-1872.
20. Nissen MJ, Bullemer P (1987): Attentional requirements of learning: Evidence from performance measures. Cogn Psychol 19:1-32.
21. Oldfield RC (1971): The assessment and analysis of handedness: The Edinburgh Inventory Neuropsychologia 6:97-113.
22. Rauch SL, Savage CR, Brown HD, Curran T, Alpert NM, Kendrick A, Fischman AJ, Kosslyn SM (1995): A PET investigation of implicit and explicit sequence learning. Hum Brain Mapping 3:271-286.
23. Rauch SL, Whalen PJ, Savage CR, Curran T, Kendrick A, Brown HD, Bush G, Breiter HC, Rosen BR (1997): Striatal recruitment during an implicit sequence learning task as measured by functional magnetic resonance imaging. Hum Brain Mapping 5:124-132.
24. Roland PE, Larsen B, Lassen NA, Skinhoj E (1980): Supplementary motor area and other cortical areas in organization of voluntary movements in man. J Neurophysiol 43:118-136.
25. Schacter DL, Tulving E (eds) (1994): Memory Systems 1994, Cambridge, MA: MIT Press.
26. Shadmehr R, Mussa-Ivaldi FA (1994): Adaptive representation of dynamics during learning a motor task. J Neurosci 14:3208-3224.
27. Talairach J, Tournoux P (1988): Co-Planar Stereotaxic Atlas of the Human Brain, New York: Thieme Medical Publishers.
28. Woods RP, Cherry SR, Mazziota JC (1992): Rapid automated algorithm for aligning and reslicing PET images. J Comput Assist Tomogr 16:620-633.