Age-related differences in distractibility and response to methylphenidate in monkeys

Cerebral Cortex

Volumn 8, Issue 2, 1998, Pages 164-172

  Prendergast, Mark A ^a,b,d   Jackson, William J ^a   Terry Jr , Alvin V ^a   Kille, Nancy J ^a   Arneric, Stephen P ^c   Decker, Michael W ^c   Buccafusco, Jerry J ^a,b  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c ABBOTT LABORATORIES   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLPHENIDATE;

AGED; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ARTICLE; ATTENTION DEFICIT DISORDER; DOSE RESPONSE; HABITUATION; HYPOPHAGIA; LOCOMOTION; MONKEY; NONHUMAN; PRIORITY JOURNAL; SHORT TERM MEMORY; STIMULUS RESPONSE;

AGING; ANIMALS; ATTENTION; CONDITIONING (PSYCHOLOGY); DOPAMINE AGENTS; FEMALE; HIPPOCAMPUS; MACACA MULATTA; MACACA NEMESTRINA; MALE; MEMORY, SHORT-TERM; METHYLPHENIDATE; REACTION TIME; TIME FACTORS;

EID: 0031890429     PISSN: 10473211     EISSN: None     Source Type: Journal    
DOI: 10.1093/cercor/8.2.164     Document Type: Article

References (22)

1. Aman MG, Marks RE, Turbott SH, Wilsher CP, Merry SN (1991) Methylphenidate and thioridazine in the treatment of intellectually subaverage children: effects on cognitive-motor performance. J Am Acad Child Adolesc Psychiat 30:816-824.
2. Arendt T, Bigl V, Tennstedt A, Arendt A (1985) Neuronal loss in different parts of the nucleus basalis is related to neurotic plaque formation in cortical target areas in Alzheimer's disease. Neuroscience 14:1-14.
3. Arnsten AFT, Contant TA (1992) Alpha-2 adrenergic agonists decrease distractibility in aged monkeys performing the delayed response task. Psychopharmacology 108:159-169.
4. Arnsten AFT, Goldman-Rakic PS (1984) Catecholamines and cognitive decline in aged nonhuman primates. Ann NY Acad Sci 444:218-234.
5. Arnsten AFT, Cai JX, Murphy BL, Goldman-Rakic PS (1994) Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys. Psychopharmacology 116:143-151.
6. Arnsten AFT, Cai JX, Steer JC, Goldman-Rakic PS (1995) Dopamine D2 receptor mechanisms contribute to age-related cognitive decline: the effects of quinpirole on memory and motor performance in monkeys. J Neurosci 15:3429-3439.
7. Arnsten AFT, Goldman-Rakic PS (1985) Alpha-2 adrenergic mechanisms in prefrontal cortex associated with cognitive decline in aged nonhuman primates. Science 230:1273-1276.
8. Bartus RT (1979) Four stimulants of the central nervous system: effects on short-term memory in young versus aged monkeys. Am Gerontol Soc 27:289-297.
9. Bartus RT, Dean RL (1979) Recent memory in aged non-human primates: hypersensitivity to visual interference during retention. Exp Aging Res 5:386-400.
10. Bartus RT, Levere TE (1977) Frontal decortication in rhesus monkeys: a test of the interference hypothesis. Brain Res 119:233-248.
11. Bartus RT, Dean RL, Fleming DL (1979) Aging in the rhesus monkey: effects on visual discrimination learning and reversal learning. J Gerontol 34: 209-219.
12. Broks P, Preston C, Traub P, Poppleton P, Ward C, Stahl SM (1988) Modeling dementia; effects of scopolamine on memory and attention. Neuropsychologia 28: 685-700.
13. Brozoski T, Brown RM, Rosvold HE, Goldman PS (1979) Cognitive deficits caused by regional depletion of dopamine in prefrontal cortex of rhesus monkey. Science 205:929-931.
14. Buccafusco JJ, Jackson WJ (1991) Beneficial effects of nicotine administered prior to a delayed matching-to-sample task in the young and aged monkey. Neurobiol Aging 12:233-238.
15. Buccafusco JJ, Jackson WJ, Terry AV, Jr, Marsh KC, Decker MW, Arneric SP (1995) Improvement in performance of a delayed matching-to-sample task by monkeys following ABT-418: a novel cholinergic channel activator for memory enhancement. Psychopharmacology 120:256-266.
16. Camp-Bruno JA, Herting RL (1994) Cognitive effects of milacemide and methylphenidate in healthy young adults. Psychopharmacology 115:46-52.
17. Charles L, Schain RJ, Zelniker T, Guthrie D (1979) Effects of methylphenidate on hyperactive children's ability to sustain attention. Pediatrics 64:412-418.
18. Costellanos FX, Giedd JN, Eckburg P, Marsh WL, Vaituzis AC, Kaysen D, Hamburger SD, Rapoport JL (1994) Quantitative morphology of the caudate nucleus in attention deficit hyperactivity disorder. Am J Psychiat 151:1791-1796.
19. Davis HP, Cohen A, Gandy M, Colombo P, VanDusseldorp G, Simolke N, Romano J (1990) Lexical priming deficits as a function of age. Behav Neurosci 104:288-297.
20. Elia J (1993) Drug treatment for hyperactive children. Therapeutic guidelines. Drugs 46:863-871.
21. Fox AM, Reider MJ (1993) Risks and benefits of drugs used in the management of the hyperactive child. Drug Safety 9:38-50.
22. Goldman PR, Rosvold HE (1970) Localization of function within the dorsolateral prefrontal cortex of the rhesus monkey. Exp Neurol 27:291-304.