Glucocorticoid-associated growth failure: Mechanisms and potential reversal

Endocrinologist

Volumn 8, Issue 1, 1998, Pages 21-30

  Allen, David B ^a,b  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b University of Wisconsin Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; CORTICOSTEROID; GLUCOCORTICOID; GROWTH HORMONE;

CHILD GROWTH; COLLAGEN SYNTHESIS; CORTICOSTEROID THERAPY; GROWTH DISORDER; GROWTH HORMONE RELEASE; HUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; REVIEW;

EID: 0031889757     PISSN: 10512144     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019616-199801000-00006     Document Type: Review

References (20)

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2. Guistina A, Wehrenberg WB: The role of glucocorticoids in the regulation of growth hormone secretion - mechanisms and clinical significance. Trends Endocrinol Metab 1992; 3: 306-11.
3. King APJ, Carter-Su C: Dexamethasone-induced antagonism of growth hormone (GH) action by down-regulation of GH binding in 3T3-F442A fibroblasts. Endocrinology 1995; 136: 4796-803.
4. Unterman TG, Phillips LS: Glucocorticoid effects on somatomedins and somatomedin inhibitors. J Clin Endocrinol Metab 1985; 61: 618-26.
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6. Barnes PJ: Inhaled glucocorticoids for asthma. N Engl J Med 1995; 332: 868-75.
7. Kamada AK, Szefler SJ, Martin RJ, et al.: Issues in the use of inhaled glucocorticoids. Am J Respir Crit Care Med 1996; 153: 1739-48.
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9. Martin AJ, McLennan LA, Landau LI, Phelan PD: The natural history of childhood asthma to adult life. Br Med J 1980; 280: 397-400.
10. Silverstein MD, Yunginger JW, Reed CE, et al.: Attained adult height after childhood asthma: effect of glucocorticoid therapy. J Allergy Clin Immunol 1997; 99: 466-74.
11. Allen DB, Bronsky EA, LaForce CF, et al.: Growth in asthmatic children treated with fluticasone propionate. J Pediatr 1997 (in press).
12. Agertoft L, Pederson S: Effects of long-term treatment with an inhaled corticosteroid on growth and pulmonary function in asthmatic children. Respir Med 1994; 88: 373-81.
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16. Selye H: Prevention of cortisone overdosage effects with the somatotropic hormone (STH). Am J Physiol 1952; 171: 381-4.
17. Allen DB, Goldberg BD: Stimulation of collagen synthesis and linear growth by growth hormone in glucocorticoid-treated children. Pediatrics 1992; 89: 416-21.
18. Tonshoff B, Haffner D, Mehls O: Efficacy and safety of growth hormone treatment in short children with renal allografts. Kidney Int 1993; 44: 199-207.
19. Allen DB, Julius JR, Breen TJ, et al.: Reversal of glucocorticoid-induced growth failure by human growth hormone [abstract]. Pediatr Res 1996; 39: 84A.
20. Horber FF, Haymond MW: Human growth hormone prevents the protein catabolic side effects of prednisone in humans. J Clin Invest 1990; 86: 265-72.