Bupivacaine-induced convulsion is suppressed by MK-801

Regional Anesthesia

Volumn 23, Issue 1, 1998, Pages 71-76

  Kasaba, Toshiharu ^a   Shiraishi, Seiji ^a   Taniguchi, Masahiko ^a   Takasaki, Mayumi ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Bupivacaine; Convulsion; Hypotension; Local anesthetics; MK 801

Indexed keywords

BUPIVACAINE; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ARTICLE; CAT; CONTROLLED STUDY; CONVULSION; DRUG EFFECT; ELECTROENCEPHALOGRAM; HEART RATE; HYPOTENSION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION;

EID: 0031889523     PISSN: 0146521X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00115550-199823010-00013     Document Type: Article

References (23)

1. Tanaka K, Yamasaki M. Blocking of cortical inhibitory synapses by intravenous lidocaine. Nature 1966: 209: 207-208.
2. Warnick JE, Kee RD, Yim GKW. The effects of lidocaine on inhibition in the cerebral cortex. Anesthesiology 1971: 34: 327-332.
3. de Jong RH, Bonin JD. Benzodiazepines protect mice from local anesthetic convulsions and deaths. Anesth Analg 1981: 60: 385-389.
4. Ikeda M, Dohi T, Tsuijimoto A. Protection from local anesthetic-induced convulsions by γ-aminobutyric acid. Anesthesiology 1982: 56: 365-368.
5. Stone TW. Glutamate as the neurotransmitter of cerebellar granule cells in the rat: Electrophysiological evidence. Br J Pharmacol 1979: 66: 291-296.
6. Baughman RW, Gilbert CD. Aspartate and glutamate as possible neurotransmitters of cells in layer 6 of the visual cortex. Nature 1980: 287: 848-850.
7. Peterson DW, Collins JF, Bradford HF. The kindled amygdala model of epilepsy: Anticonvulsant action of amino acid antagonists. Brain Res 1983: 275: 169-172.
8. Gilbert ME. The NMDA-receptor antagonist, MK-801, suppresses limbic kindling and kindled seizures. Brain Res 1989: 463: 90-99.
9. Bernards CM, Artru AA. Hexamethonium and midazolam terminate dysrhythmias and hypertension caused by intracerebroventricular bupivacaine in rabbits. Anesthesiology 1991: 74: 89-96.
10. Heavner JE. Cardiac dysrhythmias induced by infusion of local anesthetics into the lateral cerebral ventricle of cats. Anesth Analg 1986: 65: 133-138.
11. Snider RS, Niemer WT. A sterotaxic atlas of the cat brain. Chicago, University of Chicago Press, 1961.
12. Mather LE, Tucker GT. Meperidine and other basic drugs: General method for their determination in plasma. J Pharm Sci 1974: 63: 306-307.
13. Gill R, Brazell C, Woodruff GN, Kemp JA. The neuroprotective action of dizocilpine (MK-801) in the rat middle cerebral artery occlusion model of focal ischaemia. Br J Pharmacol 1991: 103: 2030-2036.
14. Park CK, Nehls DG, Graham DI, Teasdale GM, McCulloch J. The glutamate antogonist MK-801 reduces focal ischemic brain damage in the rat. Ann Neurol 1988: 24: 543-551.
15. Gotti B, Benavides J, MacKenzie ET, Scatton B. The pharmacotherapy of focal cortical ischaemia in the mouse. Brain Res 1990: 522: 290-307.
16. Skeie B, Meidell NK, Steen PA. Long-term bupivacaine infusion did not alter the acute seizure threshold to bupivacaine in rats. Anesth Analg 1988: 67: 61-63.
17. Bernards C. Carpenter RL, Rupp SM, Brown DL, Morse BV, Morell RC, Thompson GE. Effect of midazolam and diazepam premedication on central nervous system and cardiovascular toxicity. Anesthesiology 1989: 70: 318-323.
18. Malagodi MH, Munson ES, Embro WJ. Relation of etidocaine and bupivacaine toxicity to rate of infusion in rhesus monkeys. Br J Anaesth 1977: 49: 121-125.
19. Sage DJ, Feldman HS, Arthur GR, Datta S, Ferretti AM, Norway SB, Covino BG. Influence of lidocaine and bupivacaine on isolated guinea pig atria in the presence of acidosis and hypoxia. Anesth Analg 1984: 63: 1-7.
20. Liu PL, Feldman HS, Giasi R, Patterson MK, Covino BG. Comparative CNS toxicity of lidocaine, etidocaine, bupivacaine, and tetracaine in awake dogs following rapid intravenous administration. Anesth Analg 1983: 62: 375-379.
21. Chadwick HS. Toxicity and resuscitation in lidocaine-or bupivacaine-infused cats. Anesthesiology 1985: 63: 385-390.
22. de Jong Rh, Ronfeld RA, DeRosa RA. Cardiovascular effects of convulsant and supraconvulsant doses of amide local anesthetics. Anesth Analg 1982: 61: 3-9.
23. de La Coussaye JE, Eledjam JJ, Bruelle P, Lefrant JY, Bassoul B, Peray PA, Desch G, Sassine A. Mechanisms of the putative cardioprotective effect of hexamethonium in anesthetized dogs given a large dose of bupivacaine. Anesthesiology 1994: 80: 595-605.