Serum concentrations of lignocaine and its metabolite monoethylglycinexylidide during fibre-optic bronchoscopy in local anaesthesia

Respiratory Medicine

Volumn 92, Issue 1, 1998, Pages 40-43

  Milman, N ^a,b   Laub, M ^a   Munch, E P ^a   Angelo, H R ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NAESTVED HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

DEETHYLLIDOCAINE; DRUG METABOLITE; LIDOCAINE; LOCAL ANESTHETIC AGENT;

ADULT; AEROSOL; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DOSE TIME EFFECT RELATION; DRUG BLOOD LEVEL; DRUG SAFETY; FEMALE; FIBEROPTIC BRONCHOSCOPY; HUMAN; LOCAL ANESTHESIA; MALE; PRIORITY JOURNAL; TOPICAL DRUG ADMINISTRATION; UPPER RESPIRATORY TRACT;

EID: 0031889274     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0954-6111(98)90030-0     Document Type: Article

References (15)

1. Wang K-P, Mehta AC, eds. Flexible Bronchoscopy. London: Blackwell Science, 1995.
2. Milman N, Munch EP, Faurschou P et al. Fiberoptic bronchoscopy in local anaesthesia. Indications, results and complications in 1,323 examinations. Acta Endoscopica 1993; 23: 151-162.
3. Angelo HR, Bonde J, Kampmann JP, Kastrup J. A HPLC method for simultaneous determination of disopyramide, lidocaine, and monodealkylated metabolites. Scand J Clin Lab Invest 1986; 46: 623-627.
4. Jacoby O. On anaesthesia for bronchoscopy. Ugeskr Laeg 1951; 113: 520-525.
5. Simpson FG, Arnod AG, Purvis A et al. Postal survey of bronchoscopic practice by physicians in the United Kingdom. Thorax 1986; 41: 311-317.
6. Boye NP, Bredesen JE. Plasma concentrations of lidocaine during inhalation anaesthesia for fiberoptic bronchoscopy. Scand J Respir Dis 1979; 60: 105-108.
7. Keane D, McNicholas WT. Comparison of nebulized and sprayed topical anaesthesia for fibreoptic bronchoscopy. Eur Respir J 1992; 5: 1123-1125.
8. Patterson JR, Blaschke TF, Hunt Jr KK, Meffin PJ. Lidocaine blood concentrations during fibreoptic bronchoscopy. Am Rev Respir Dis 1975; 112: 53-57.
9. Efthimiou J, Higenbottam T, Holt D, Cochrane GM. Plasma concentrations of lignocaine during fibreoptic bronchoscopy. Thorax 1982; 37: 68-71.
10. Tucker GT, Mather LE. Properties, absorption, and disposition of local anesthetic agents. In: Cousins MJ, Bridenbaugh PO, eds. Neural Blockade in Clinical Anesthesia and Management of Pain, 2nd ed. London: JB Lippincott, 1987: 47-110.
11. Breuer HWM, Krengel C, Heil E, Worth H. Side effects of topical anesthesia during fiberoptic bronchoscopy. Eur J Respir Dis 1988; 2: 391S.
12. Arthur GR. Pharmacokinetics of local anesthetics. In Strichartz GR, ed. Local Anesthetics, Handbook of Experimental Pharmacology, 1986; 81: 165-186.
13. Benowitz NL, Meister W. Clinical pharmacokinetics of lignocaine. Clin Pharmacokinet 1978; 3: 177-201.
14. Covino BG. Toxicity and systemic effects of local anesthetic agents. In: Strichartz GR, ed. Local Anesthetics, Handbook of Experimental Pharmacology, 1986; 81: 187-212.
15. Harrison DC, Stenson RE, Constantino RT. The relationship of blood levels, infusion rates, and metabolism of lidocaine to its antiarrhythmic action. In: Sandøe E, Flensted-Jensen E, Olesen KH, eds. Symposium on Cardiac Arrhythmias. Göteborg: Astra AB, 1970: 427-447.