A randomized clinical trial comparing an extended-use hygroscopic condenser humidifier with heated-water humidification in mechanically ventilated patients

Chest

Volumn 113, Issue 3, 1998, Pages 759-767

  Kollef, Marin H ^a   Shapiro, Steven D ^a   Boyd, Vanessa ^b   Silver, Patricia ^b   Von Harz, Benjamin ^b   Trovillion, Ellen ^b   Prentice, Donna ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BARNES JEWISH HOSPITAL   (United States)

Author keywords

Airway humidification; Intensive care; Mechanical ventilation; Outcomes; Ventilator associated pneumonia

Indexed keywords

OXYGEN; WATER;

ADULT; AGED; ARTERIAL OXYGEN TENSION; ARTICLE; ARTIFICIAL VENTILATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; ENDOTRACHEAL TUBE; FEMALE; HEAT EXCHANGE; HOSPITALIZATION; HUMAN; HUMIDIFIER; INTENSIVE CARE UNIT; LUNG GAS EXCHANGE; MAJOR CLINICAL STUDY; MALE; MOISTURE; MORTALITY; MULTIPLE ORGAN FAILURE; PNEUMONIA; PRIORITY JOURNAL; VENTILATOR; WETTABILITY;

EID: 0031888824     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.113.3.759     Document Type: Article

References (35)

1. Chalon J, Loew D, Malebranche J. Effect of dry anesthetic gases or tracheobronchial epithelium. Anesthesiology 1972; 37:338-43
2. Marfatia S, Donahoe PK, Hendren WH. Effect of dry and humidified gases on the respiratory epithelium in rabbits. J Pediatr Surg 1975; 10:583-87
3. Williams R, Rankin N, Smith T, et al. Relationship between the humidity and temperature of inspired gases and the function of the airway mucosa. Crit Care Med 1996; 24:1920-29
4. Fonkalsrud EW, Sanchez M, Higashijima I, et al. A comparative study of the effects of dry vs humidified ventilation on canine lungs. Surgery 1975; 78:373-80
5. Hirsch JA, Tokayer JL, Robinson MJ, et al. Effects of dry air and subsequent huminidification on tracheal mucous velocity in dogs. J Appl Physiol 1975; 39:242-46
6. Hess DR, Kacmarek RM. Essentials of mechanical ventilation. New York: McGraw-Hill, 1996; 33-40
7. Craven DE, Goularte TA, Make BJ. Contaminated condensate in mechanical ventilator circuits: a risk factor for nosocomial pneumonia? Am Rev Respir Dis 1984; 129:625-28
8. Martin C, Thomachot L, Quinio B, et al. Comparing two heat and moisture exchangers with one vaporizing humidifier in patients with minute ventilation greater than 10 L/min. Chest 1995; 107:1411-15
9. Miyao H, Hirokawa T, Miyasaka K, et al. Relative humidity, not absolute humidity, is of great importance when using a humidifier with a heating wire. Crit Care Med 1992; 20:674-79
10. Mebius CA. Comparative evaluation of disposable humidifiers. Acta Anaesthesiol Scand 1983; 27:403-09
11. Martin C, Perrin G, Gevaudan M-J, et al. Heat and moisture exchangers and vaporizing humidifiers in the intensive care unit. Chest 1990; 97:144-49
12. Branson RD, Chatburn RL. Humidification of inspired gases during mechanical ventilation. Respir Care 1993; 38:461-68
13. Branson RD. Artificial noses: the unanswered questions. Respir Care 1989; 34:969-71
14. Misset B, Escudier B, Rivara D, et al. Heat and moisture exchanger vs heated humidifier during long-term mechanical ventilation: a prospective randomized study. Chest 1991; 100:160-63
15. Branson RD, Davis K, Campbell RS, et al. Humidification in the intensive care unit: prospective study of a new protocol utilizing heated humidification and a hygroscopic condenser humidifier. Chest 1993; 104:1800-05
16. Djedaini K, Billiard M, Mier L, et al. Changing heat and moisture exchangers every 48 hours rather than 24 hours does not affect their efficacy and the incidence of nosocomial pneumonia. Am J Respir Crit Care Med 1995; 152:1562-69
17. Dreyfuss D, Djedaini K, Gros I, et al. Mechanical ventilation with heated humidifiers or heat and moisture exchangers: effects on patient colonization and incidence of nosocomial pneumonia. Am J Respir Crit Care Med 1995; 151:986-92
18. Hess D, Burns E, Romagnoli D, et al. Weekly ventilator circuit changes: a strategy to reduce costs without affecting pneumonia rates [see comments]. Anesthesiology 1995; 82:903-11
19. Dreyfuss D, Djedaini K, Weber P, et al. Prospective study of nosocomial pneumonia and of patient and circuit colonization during mechanical ventilation with circuit changes every 48 hours versus no change. Am Rev Respir Dis 1991; 143:738-43
20. Kollef MH, Shapiro SD, Fraser VJ, et al. Mechanical ventilation with or without 7-day circuit changes: a randomized controlled trial [see comments]. Ann Intern Med 1995; 123:168-74
21. Kollef MH, Prentice D, Shapiro SD, et al. Mechanical ventilation with or without daily changes of in-line suction catheters. Am J Respir Crit Care Med 1997; 156:466-72
22. Menzies R, Gibbons W, Goldberg P. Determinants of weaning and survival among patients with COPD who require mechanical ventilation for acute respiratory failure. Chest 1989; 95:398-405
23. Knaus WA, Draper EA, Wagner DP, et al. APACHE II: a severity of disease classification system. Crit Care Med 1985; 13:818-29
24. Rubin DB, Wiener-Kronish JP, Murray JF, et al. Elevated von Willebrand factor antigen is an early phase predictor of acute lung injury in nonpulmonary sepsis syndrome. J Clin Invest 1990; 86:474-80
25. Pingleton SK, Fagon JY, Leeper KY Jr. Patient selection for clinical investigation of ventilator-associated pneumonia: criteria for evaluating diagnostic techniques. Chest 1992; 102: 553S-56S
26. SAS/STAT user's guide. (vol 2). Cary. NC: SAS Institute, 1990; 1071-1126
27. Cohen IL, Weinberg PF, Fein A, et al. Endotracheal tube occlusion associated with the use of heat and moisture exchangers in the intensive care unit. Crit Care Med 1988; 16:277-79
28. Roustan JP, Kienlen J, Aubas P, et al. Comparison of hydrophobic heat and moisture exchangers with heated humidifier during prolonged mechanical ventilation. Intensive Care Med 1992; 18:97-100
29. Suzukawa M, Usada Y, Numata K. The effects of sputum characteristics of combining an unheated humidifier with a heat-moisture exchanging filter. Respir Care 1989; 34:976-84
30. Gallagher J, Strangeways JE, Allt-Graham J. Contamination control in long-term ventilation: a clinical study using a heat-anil moisture-exchanging filter. Anaesthesia 1987; 42:476-81
31. Kirton O, DeHaven B, Morgan J, et al. Different rates of nosocomial ventilator associated pneumonia (VAP) with HME/ filters (HMEF) and heated wire humidification: a prospective, randomized trial [abstract]. Intensive Care Med 1996; 22:S326
32. Timsit JF, Chevret S, Valcke J, et al. Mortality of nosocomial pneumonia in ventilated patients: influence of diagnostic tools. Am J Respir Crit Care Med 1996; 154:116-23
33. Bregeon F, Papazian L, Visconti A, et al. Relationship of microbiologic diagnostic criteria to morbidity and mortality in patients with ventilator-associated pneumonia. JAMA 1997; 277:655-62
34. Martinez FJ, Pietchei S, Wise C, et al. Increased resistance of hygroscopic condenser humidifiers when using a closed circuit suction system. Crit Care Med 1994; 22:1668-73
35. Rosi R, Buscalferri A, Monfregola MR, et al. Systemic lithium resorption from lithium-chloride-coated heat and moisture exchangers. Intensive Care Med 1995; 21:937-40