Effects of intravenous nicardipine in Chinese patients with hypertensive emergencies

Current Therapeutic Research - Clinical and Experimental

Volumn 59, Issue 3, 1998, Pages 188-195

  Tao, Ping ^a   Zheng, De Yu ^a   Yu, Xia Jun ^b  

^a FUWAI HOSPITAL   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Calcium channel blocker; Hypertensive emergency; Nicardipine

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; NICARDIPINE;

ADULT; AGED; ARTICLE; BOLUS INJECTION; CHINESE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; EMERGENCY; FEMALE; HEART RATE; HOT FLUSH; HUMAN; HYPERTENSION; HYPOTENSION; INFUSION; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; NOSE CONGESTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SYSTOLIC BLOOD PRESSURE; XEROSTOMIA;

EID: 0031888715     PISSN: 0011393X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0011-393X(98)85016-9     Document Type: Article

References (20)

1. Abdelwahab W, Frishman W, Landau A. Management of hypertensive urgencies and emergencies. J Clin Pharmacol. 1995;35:747-762.
2. Cotton DB, Gonik B, Dorman KF. Cardiovascular alterations in severe pregnancy-induced hypertension seen with an intravenously given hydralazine bolus. Surg Gynecol Obstet. 1985;161:240-244.
3. Garett BN, Kaplan NM. Efficacy of slow infusion of diazoxide in the treatment of severe hypertension without organ hypoperfusion. Am Heart J. 1982;103:390-394.
4. Flaherty JT, Magee PA, Gardner TL, et al. Comparison of intravenous nitroglycerin and sodium nitroprusside for treatment of acute hypertension developing after coronary artery bypass surgery. Circulation. 1982;65:1072-1077.
5. Yoshinaga K, Iimura O, Abe K, et al. Trial of clinical usefulness of nicardipine hydrochloride injection on hypertensive emergencies and urgencies. J Clin Exp Med. 1993;165: 437-456.
6. Bertel O, Conen LD. Treatment of hypertensive emergencies with the calcium channel blocker nifedipine. Am J Med. 1985;79(Suppl 4A):32-35.
7. DiPette DJ, Ferraro JC, Evans RR, et al. Enalaprilat, an intravenous angiotensin converting enzyme inhibitor, in hypertensive crises. Clin Pharmacol Ther. 1985;38:199-204.
8. Aroney CN, Semigran MJ, Dec GW, et al. Inotropic effects of nicardipine in patients with heart failure: Assessment by left ventricular and systolic pressure volume analysis. J Am Coll Cardiol. 1989;14:1331-1338.
9. Charles RL, Lambert CR, Pepine CJ. Acute antianginal hemodynamic effects of nicardipine in coronary artery disease. Am Heart J. 1990;119:457-462.
10. Takenaka T, Handa J. Cerebrovascular effects of YC-93, a new vasodilator in dogs, monkeys, and human patients. Int J Clin Pharmacol Biochem. 1979;17:1-11.
11. Yoshinaga K, Iinuma O, Abe K. Antihypertensive efficacy and usefulness of nicardipine sustained release formulation (YC-93LA) in patients with essential hypertension. J Clin Exp Med. 1987;140:691-715.
12. Ohtomo E. Clinical efficacy of YC-93 (nicardipine hydrochloride) on disturbance of cerebral vascular disease. Clin Rep. 1979;13:1207-1213.
13. Goldberg ME, Clark S, Joseph J, et al. Nicardipine versus placebo for the treatment of postoperative hypertension. Am Heart J. 1990;119:446-450.
14. Halpern NA, Alicea M, Karakoff LR, et al. Postoperative hypertension: A prospective, placebo-controlled, randomized, double-blind trial, with intravenous nicardipine hydrochloride. Angiology. 1990;41:992-1004.
15. Wallin JD, Cook ME, Blanski L, et al. Intravenous nicardipine for the treatment of severe hypertension. Am J Med. 1988;85:331-338.
16. Clifton GG, Wallin JD. Intravenous nicardipine: An effective new agent for the treatment of severe hypertension. Angiology. 1990;41:1005-1009.
17. Dow RJ, Graham DJM. A review of the human metabolism and pharmacokinetics of nicardipine hydrochloride. Br J Clin Pharmacol. 1986;22:195S-202S.
18. Campbell B, Kelman A, Sumner D, et al. Non-invasive measurement of the acute haemodynamic effects of a new calcium channel blocker, nicardipine. Br J Clin Pharmacol. 1984;17:188P-189P.
19. Jamieson MJ, Jeffers TA, Dow R. Nicardipine infusion: Pharmacokinetics, haemodynamics and effects on the systolic time intervals. Br J Clin Pharmacol. 1985;19:536P.
20. Neutel JM, Smith DH, Wallin D, et al. A comparison of intravenous nicardipine and sodium nitroprusside in the immediate treatment of severe hypertension. Am J Hypertens. 1994;7:623-628.