Glomerular pathology: Recent advances

Journal of Pathology

Volumn 184, Issue 2, 1998, Pages 123-129

  Gibson, I W ^a   More, I A R ^a  

^a WESTERN INFIRMARY   (United Kingdom)

Author keywords

Glomerular basement membrane; Glomerular pathology; Glomerulonephritis; Glomerulopathy

Indexed keywords

FOCAL GLOMERULOSCLEROSIS; GLOMERULONEPHRITIS; GLOMERULUS BASEMENT MEMBRANE; GLOMERULUS EPITHELIUM; IMMUNE COMPLEX NEPHRITIS; INFLAMMATORY INFILTRATE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW;

BASEMENT MEMBRANE; GLOMERULONEPHRITIS; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HIV INFECTIONS; HUMANS; KIDNEY DISEASES; KIDNEY GLOMERULUS; NEPHROTIC SYNDROME;

EID: 0031888651     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199802)184:2<123::AID-PATH16>3.0.CO;2-X     Document Type: Review

References (96)

1. Couser WG. Pathogenesis of glomerulonephritis. Kidney Int 1993; 44: S19-S26.
2. Johnson RJ, Lovett D, Lehrer RJ, Couser WG, Klebanoff SJ. Role of oxidants and proteases in glomerular injury. Kidney Int 1994; 45: 352-359.
3. Brady HR. Leucocyte adhesion molecules and kidney diseases. Kidney Int 1994; 45: 1285 1300.
4. Johnson RJ. Platelets in inflammatory glomerular injury. Semin Nephrol 1991; 11: 276-284.
5. Main IW, Nikolic-Paterson DJ, Atkins RC. T cells and macrophages and their role in renal injury. Semin Nephrol 1992; 12: 393-407.
6. Couser WG, Johnson RJ. Mechanisms of progressive renal disease in glomerulonephritis. Am J Kidney Dis 1994; 23: 193-198.
7. Johnson RJ, Floege JF, Yoshimura A, lida H, Couser WG, Alpers CE. The activated mesangial cell: a glomerular 'myofibroblast'. J Am Soc Nephrol 1992; 2: 5190-5197.
8. Yoshioka K, Takemura T, Murakami K, et al. Transforming growth factor-β protein and mRNA in glomeruli in normal and diseased human kidneys. Lab lnvest 1993; 68: 154 163.
9. Young B, Johnson RJ, Alpers C, et al. Cellular events in the evolution of experimental diabetic nephropathy. Kidney Int 1995; 47: 935-944.
10. Kopp JB, Factor VM, Mozes M, et al. Transgenic mice with increased plasma levels of TGF-β1 develop progressive renal disease. Lab Invest 1996; 74: 991-1003.
11. Farquhar MG. Molecular analysis of the pathological autoimmune antigens of Heymann nephritis. Am J Pathol 1996; 148: 1331-1337.
12. Farquhar MG, Saito A, Orlando RA. The Heymann nephritis antigenic complex: megalin (gp330) and RAP. J Am Soc Nephrol 1995; 6: 35 47.
13. Neale TJ, Ullrich R, Ojha P, Poczewski H, Verhoeven AJ, Kerjaschki D. Expression of a neutrophil respiratory burst cytochrome and reactive oxygen species in kidney glomeruli in association with proteinuria in passive Heymann nephritis. Proc Natl Acad Sci USA 1993; 90: 3645-3649.
14. Cavallo T. Membranous nephropathy: insights from Heymann nephritis. Am J Pathol 1994; 144: 651-658.
15. Tryggvason K. Biochemistry and genetic disease of the glomerular basement membrane. Semin Nephrol 1993; 5: 447-456.
16. Furness PN. Basement membrane synthesis and degradation. J Pathol 1997; 183: 1-3
17. Feingold J, Bois E, Chompret A, Broyer M, Gubler MC, Grunfeld JP. Genetic heterogeneity ot Alport syndrome. Kidney Int 1985; 27: 672-677.
18. Gubler M, Levy M, Broyer M, et al. Alport syndrome: a report of 58 cases and a review of the literature. Am J Med 1981; 70: 493-505.
19. Churg J, Sherman RL. Pathologic characteristics of hereditary nephritis. Arch Pathol 1973; 95: 374-379.
20. Hill GS, Jenis EH, Goodloe S. The nonspecificity of the ultrastructural alterations in hereditary nephritis: with additional observations on benign familial hematuria. Lab Invest 1974; 31: 516-532.
21. Habib R, Gubler MC, Hinglais N, et al. Alporl syndrome: experience at Hôpital Necher. Kidney Int 1982; 21: 520.
22. Kleppel MM, Kashtan CE, Butkowski RJ, Fish AJ, Michael AF, Alport familial nephritis. Absence of 28 kilodalton non-collagenous monomers of type IV collagen in glomerular basement membrane. J Clin Invest 1987; 80: 263-266.
23. Hostikka SL, Eddy RL, Byers MG, Hoyhtya M, Shows TB, Tryggvason K. Identification of a distinct type IV collagen α chain with restricted kidney distribution and assignment of its gene to the locus of X chromosome-linked Alport syndrome. Proc Natl Acad Sci USA 1990; 87: 1606-1610.
24. Atkin CL, Hasstedt SJ, Menlove L, et al. Mapping of Alport syndrome to the long arm of the X chromosome. Am J Hum Genet 1988; 42: 249-255.
25. Barker DF, Hostikka SL, Zhou J, et al. Identification of mutations in the COL4A5 collagen gene in Alport syndrome. Science 1990; 248: 1224-1227.
26. Antignac C, Dechenes G, Gros F, Knebelmann B, Tryggvason K, Gubler MC. Mutations in the COL4A5 gene in Alport syndrome. J Am Soc Nephrol 1991; 2: 249.
27. Zhou J, Barker DF, Hostikka SL, Gregory MC, Atkin CL, Tryggvason K. Single base mutation in alpha-5(IV) collagen chain gene converting a conserved cysteine to serine in Alport syndrome. Genomics 1991; 9: 10-18.
28. Tryggvason K, Zhou J, Hostikka SL, Shows TB. Molecular genetics of Alport syndrome. Kidney Int 1993; 43: 38-44.
29. Kalluri R, Weber M, Netzer KO, et al. COL4A5 gene deletion and production of post transplant anti-α3(IV) collagen alloantibodies in Alport syndrome. Kidney Int 1994; 45: 721-726.
30. Kashtan CE, Michael AF, Kleppel MM. Alport syndrome: association of deletions in the COL4A5 gene with post-transplant anti-GBM nephritis. J Am Soc Nephrol 1991; 2: 256.
31. Naito I, Kawai S, Nomura S, et al. Relationship between COL4A5 gene mutation and distribution of type IV collagen in male X-linked Alport syndrome. Kidney Int 1996; 50: 304-311.
32. Zhou J, Mochizuki T, Smeets H, et al. Deletions of the paired α5(IV) and α6(IV) collagen genes in inherited smooth muscle tumours. Science 1993; 261: 1167-1169.
33. Mochizuki T, Lemmink HH, Mariyama M, et al. Identification of mutations in the α3(IV) and α4(IV) collagen genes in autosomal recessive Alport syndrome. Nature Genet 1994; 8: 77-82.
34. Gubler MC, Knebelmann B, Beziau A, et al. Autosomal recessive Alport syndrome: immunohistochemical study of type IV collagen distribution. Kidney Int 1995; 47: 1142-1147.
35. Olsen DL, Anand SK, Landing BH, Heuser E, Grushkin CM, Lieberman E. Diagnosis of hereditary nephritis by failure of glomeruli to bind antiglomerular basement membrane antibodies. J Pediatr 1980; 96: 697-699.
36. Weislander J, Barr JF, Butkowski R, et al. Goodpasture antigen of the glomerular basement membrane: localisation of noncollagenous regions of type IV collagen. Proc Natl Acad Sci USA 1984; 81: 3838-3842.
37. Saus J, Weislander J, Langeveld JPM, Quinones S, Hudson BG. Identification of the Goodpasture antigen as the α3(IV) chain of collagen IV. J Biol Chem 1988; 263: 13374-13380.
38. Hudson BG, Kalluri R, Gunwar S, et al. Molecular characteristics of the Goodpasture autoantigen. Kidney Int 1993; 43: 135-139.
39. Hudson BG, Kalluri R, Tryggvason K. Pathology of glomerular basement membrane nephropathy. Curr Opin Nephrol Hypertension 1994; 3: 334-339.
40. Savin VJ. Mechanisms of proteinuria in non-inflammatory glomerular diseases. Am J Kidney Dis 1993; 21: 347-362.
41. Savin VJ, Sharma R, Sharma M, et al. Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis. N Engl J Med 1996; 334: 878-883.
42. Artero ML, Sharma R, Savin VJ, Vincenti F. Plasmapheresis reduces proteinuria and serum capacity to injure glomeruli in patients with recurrent focal glomerulosclerosis. Am J Kidney Dis 1994; 23: 574-581.
43. Dantal J, Bigot E, Bogers W, et al. Effect of plasma protein adsorption on protein excretion in kidney transplant recipients with recurrent nephrotic syndrome. N Engl J Med 1994; 330: 7-14.
44. Jennette JC, Falk RJ. Pathogenetic potential of anti-neutrophil cytoplasmic autoantibodies. Lab Invest 1994; 70: 135-137.
45. Savage COS, Cooke SP. The role of the endothelium in systemic vasculitis. J Autoimmun 1993; 6: 237-249.
46. Falk RJ, Terrell R Charles LA, Jennette JC. Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to dearanulate and produce oxygen radicals. Proc, Natl Acad Sci USA 1990; 87: 4115-4119.
47. Ewert BH, Jennette JC, Falk RJ. Anti-myeloperoxidase antibodies stimulate neutrophils to damage human endothelial cells. Kidney Int 1992; 41: 375-383.
48. Kallenberg CGM, Brouwer E, Weening J, Cohen-Tervaert JWC. Antineutrophil cytoplasmic antibodies: current diagnostic and pathophysiologic potential. Kidney Int 1994; 46: 1-15.
49. Jayne DRW, Gaskin G, Pusey CD, et al. ANCA and predicting relapse in systemic vasculitis. Q J Med 1995; 88: 127-133.
50. De Oliviera J, Gaskin G, Dash A, et al. Relationship between disease activity and anti-neutrophil cytoplasmic antibody (ANCA) concentration in long term management of systemic vasculitis. Am J Kidney Dis 1995; 25: 380-389.
51. Bonsib SM, Goeken JA, Kemp JD, Chandran P, Shadur C, Wilson L. Co-existent anti-neutrophil cytoplasmic antibody and anti-glomerular basement membrane antibody associated disease-report of six cases. Mod Pathol 1993; 6: 526-530.
52. Schwartz MM, Korbet SM. Primary focal segmental glomerulosclerosis. Pathology, pathogenesis and relationship to secondary forms. Am J Kidney Dis 1993; 22: 874-883.
53. Schwartz MM, Lewis EJ. Focal segmental glomerular sclerosis: the cellular lesion. Kidney Int 1985; 28: 968-974.
54. Korbet SM, Schwartz MM, Lewis EJ. Recurrent nephrotic syndrome in renal allografts. Am J Kidney Dis 1988; 11: 270-276.
55. Korbet SM, Rydel J, Schwartz MM, Lewis EJ. The prognosis of FSGS in adults. J Am Soc Nephrol 1993; 4: 280.
56. Schwartz MM, Korbet SM, Rydel J, Borok R, Genchi R. Primary focal segmental glomerular sclerosis in adults: prognostic value of histological variants. Am J Kidney Dis 1995; 25: 845-852.
57. Weiss MA, Daquioag E, Margolin EG, Pollack VE. Nephrotic syndrome, progressive irreversible renal failure and glomerular 'collapse': a new clinicopathologic entity? Am J Kidney Dis 1986; 7: 20-28.
58. Detwiler RK, Falk RJ, Hogan SL, Jennette JC. Collapsing glomerulopathy: a clinically and pathologically distinct variant of focal segmental glomerulosclerosis. Kidney Int 1994; 45: 1416-1424.
59. D'Agati V, Suh JI, Carbone L, Cheng J-T. Appel GB. Pathology of HIV-associated nephropathy: a detailed morphologic and comparative study. Kidney Int 1989; 35: 1358-1370.
60. Humphrey's MH. Human immunodeficiency virus-associated glomerulosclerosis. Kidney Int 1995; 48: 311-320.
61. Cohen AH, HIV-associated nephropathy: racial difference in severity of renal damage. J Am Soc Nephrol 1990; 1: 305.
62. Smith SR, Svetkey LP, Dennis VW. Racial differences in the incidence and progression of renal diseases. Kidney Int 1990; 40: 815-822.
63. Rich SA. De novo synthesis and secretion of a 36-kD protein by cells that form lupus inclusions in response to alpha-interferon. J Clin Invest 1995; 95: 219-223.
64. Cohen AH, Nast CC. HIV-associated nephropathy. A unique combined glomerular, tubular and interstitial lesion. Mod Pathol 1988; 1: 87-97.
65. Green DF, Resnick L, Gourgoignie JJ. HIV infects endothelial and mesangial but not epithelial cells. Kidney Int 1992; 41: 956-960.
66. Kimmel PL, Ferreira-Centeno A, Farkas-Szallasi T, Abraham AA, Garrett CT. Viral DNA in microdissected renal biopsy tissue from HIV infected patients with nephrotic syndrome. Kidney Int 1993; 43: 1347-1352.
67. Kopp JB, Klotman ME, Adler SH, et al. Progressive glomerulosclerosis and enhanced renal accumulation of basement membrane components in mice transgenic for human immunodeficiency virus type I genes. Proc Natl Acad Sci USA 1992; 89: 1577-1581.
68. Kopp JB, Ray PE, Adler SH, et al. Nephropathy in HIV-transgenic mice. Contr Nephrol 1994; 107: 194-204.
69. Ray PE, Bruggeman LA, Weeks BS, et al. βFGF and its low affinity receptors in the pathogenesis of HIV-associated nephropathy in transgenic mice. Kidney Int 1994; 46: 759-772.
70. Detwiler RK, Hogan SL, Falk RJ, Jennette JC. Collapsing glomerulopathy in renal transplant patients: recurrence, and de novo occurrence. J Am Soc Nephrol 1996; 7: 1331 (Abstract).
71. Rosenmann E, Eliakim M. Nephrotic syndrome associated with amyloidlike glomerular deposits. Nephron 1977; 18: 301-308.
72. Alpers CE, Rennke HG, Hopper J Jr, Biava C. Fibrillary glomerulonephritis: an entity with unusual immunofluorescence features. Kidney Int 1987; 31: 781-789.
73. Schwartz MM, Lewis EJ. The quarterly case: nephrotic syndrome in a middle aged man. Ultastruct Pathol 1980; 1: 575-582.
74. Iskander SS, Falk RJ, Jennette JC. Clinical and pathologic features of fibrillary glomerulonephritis. Kidney Int 1992; 42: 1401-1407.
75. Fogo A, Qureshi N, Horn RG. Morphologic and clinical features of fibrillary glomerulonephritis versus immunotactoid glomerulopathy. Am J Kidney Dis 1993; 22: 367-377.
76. Alpers CE. Immunotactoid (microtubular) glomerulopathy: an entity distinct from fibrillary glomerulonephritis? Am J Kidney Dis 1992; 19: 185 191.
77. Masson RG, Rennke HG, Gorrleib MN. Pulmonary hemorrhage in a patient with fibrillary glomerulonephritis. N Engl J Med 1992; 326: 36 39.
78. Calls Ginestra J, Torras A, Ricart MJ, et al. Fibrillary glomerulonephritis and pulmonary hemorrhage in a patient with renal transplantation. Clin Nephrol 1995; 43: 180-183.
79. Korbet SM, Rosenberg BF, Schwanz MM, Lewis EJ. Course of renal transplantation in immunotactoid glomerulopathy. Am J Med 1990; 89: 91-95.
80. Korbet SM, Schwartz MM, Lewis EJ. Immunotactoid glomerulopathy. Am J Kidney Dis 1991; 17: 247-257.
81. Alpers CE. Fibrillary glomerulonephritis and immunotactoid glomerulopathy: two entities, not one. Am J Kidney Dis 1993: 22: 448-451.
82. Schwanz M M. Immunotactoid glomerulopathy: the case for Occum's razor. Am J Kidney Dis 1993; 22: 446-147.
83. Mazzucco G, Maran E, Rollino C, Monga G. Glomerulonephritis with organized deposits: a mesangiopathic, not immune complex-mediated disease? A pathologic study of two cases in the same family. Hum Pathol 1992; 23: 63-68.
84. Strom EH, Banfi G, Krapf R, et al. Glomerulopathy associated with predominant fibronectin deposits: a newly recognised hereditary disease. Kidney Int 1995; 48: 163-170.
85. Assmann KJ, Koene RA, Wetzels JF. Familial glomerulonephritis characterised by massive deposits of fibronectin. Am J Kidney Dis 1995; 25: 781-791.
86. Hoyer JR, Michael AF, Vernier RL. Renal disease in nail-patella syndrome: clinical and morphologic studies. Kidney Int 1972; 2: 231-238.
87. Dombros N, Katz A. Nail patella-like renal lesions in the absence of skeletal abnormalities. Am J Kidney Dis 1982; 1: 237-240.
88. Salcedo JR. An autosomal recessive disorder with glomerular basement membrane abnormalities similar to those seen in the nail patella syndrome: report of a kindred. Am J Med Genet 1984; 19: 579-584.
89. Gubler MC, Dommergues JP, Furioli J, et al. Nail-patella syndrome without extra-renal lesions. A new hereditary glomerular nephropathy. Ann Pediatr (Paris) 1990; 37: 78-82.
90. McPhail AH, Harvey DL, Falk RJ, Jennette JC. Collagen glomerulopathy: a pathologically distinct disease. Mod Pathol 1993; 6: 118 (Abstract).
91. Yoshida F, Yuzawa Y, Shigematsu H, et al. Nephrotic syndrome with massive accumulation of type I and type III collagen in the glomeruli. Intern Med 1993; 32: 171-176.
92. Ikeda K, Yokoyama H, Tomosugi N, Kida H, Ooshima A, Kobayashi K. Primary glomerular fibrosis: a new nephropathy caused by diffuse intraglomerular increase in atypical type III collagen fibres. Clin Nephrol 1990; 33: 155-159.
93. Imbasciati E, Gherardi G, Morozumi K, et al. Collagen type III glomerulopathy: a new idiopathic glomerular disease. Am J Nephrol 1991; 11: 422-429.
94. Mizuiri S, Hasegawa A, Kikuchi A, Amagasaki Y, Nakamura N, Sakaguchi H. A case of collagenofibrotic glomerulopathy associated with hepatic perisinusoidal fibrosis. Nephron 1993; 63: 183-187.
95. Gubler MC, Dommergues JP, Foulard M, et al. Collagen type III glomerulopathy: a new type of hereditary nephropathy. Peldiatr Nephrol 1993; 7: 354-360.
96. Tamura H, Matsuda A, Kidoguchi N, Matsumura O, Mitarai T, Isoda K. A family with two sisters with collagenofibrotic glomerulonephropathy. Am J Kidney Dis 1996; 27: 588-595.