The N-terminal portion of parathyroid hormone-related protein mediates the inhibition of apical Na+/H+ exchange in opossum kidney cells

Journal of the American Society of Nephrology

Volumn 9, Issue 2, 1998, Pages 175-181

  Maeda, Shigeto ^a   Wu, Shouxing ^a   Green, Jacob ^a   Kim, Hyunsook ^b   Bosch, Ricardo ^b   Lee, Ivan ^b   Adams, John ^a   Clemens, Thomas L ^a   Kurtz, Ira ^b,c  

^a UNIVERSITY OF CINCINNATI   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPORTER; CALCIUM ION; CYCLIC AMP; INOSITOL PHOSPHATE; PARATHYROID HORMONE; PARATHYROID HORMONE RELATED PROTEIN; PROTEIN KINASE C; PROTON; SODIUM ION;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FLUORESCENCE MICROSCOPY; KIDNEY CELL; NONHUMAN; OPOSSUM; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; SIGNAL TRANSDUCTION;

EID: 0031888171     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Martin TJ, Moseley JM, Gillespie MT: Parathyroid hormone-related protein: Biochemistry and molecular biology [Review]. Crit Rev Biochem Mol Biol 26: 377-395, 1991
2. Orloff JJ, Reddy D, de Papp AE, Yang KH, Soifer NE, Stewart AF: Parathyroid hormone-related protein as a prohormone: Post-translational processing and receptor interactions [Review]. Endocr Rev 15: 40-60, 1994
3. Thiede M, Rodan G: Expression of a calcium mobilizing parathyroid hormone-like peptide in lactating mammary tissue. Science 242: 278-280, 1988
4. Kremer R, Karaplis AC, Henderson J, Gulliver W, Banville D, Hendy GN, Goltzman D: Regulation of parathyroid hormone-like peptide in cultured normal human keratinocytes: Effect of growth factors and 1,25 dihydroxyvitamin D3 on gene expression and secretion. J Clin Invest 87: 884-893, 1991
5. Hongo T, Kupfer J, Enomoto H, Sharifi B, Giannella-Neto D, Forrester JS, Singer FR, Goltzman D, Hendy GN, Pirola C: Abundant expression of parathyroid hormone-related protein in primary rat aortic smooth muscle cells accompanies serum-induced proliferation. J Clin Invest 88: 1841-1847, 1991
6. Thiede MA, Daifotis AG, Weir EC, Brines ML, Burtis WJ, Ikeda K, Dreyer BE, Garfield RE, Broadus AE: Intrauterine occupancy controls expression of the parathyroid hormone-related peptide gene in preterm rat myometrium. Proc Natl Acad Sci USA 87: 6969-6973, 1990
7. Thiede MA, Harm SC, McKee RL, Grasser WA, Duong LT, Leach RM Jr: Expression of the parathyroid hormone-related protein gene in the avian oviduct: Potential role as a local modulator of vascular smooth muscle tension and shell gland motility during the egg-laying cycle. Endocrinology 129: 1958-1966, 1991
8. Streutker C, Drucker DJ: Rapid induction of parathyroid hormone-like peptide gene expression by sodium butyrate in a rat islet cell line. Mol Endocrinol 5: 703-708, 1991
9. Weir EC, Brines ML, Ikeda K, Burtis WJ, Broadus AE, Robbins RJ: Parathyroid hormone-related peptide gene is expressed in the mammalian central nervous system. Proc Natl Acad Sci USA 87: 108-112, 1990
10. Soifer NE, Van Why SK, Ganz MB, Kashgarian M, Siegel NJ, Stewart AF: Expression of parathyroid hormone-related protein in the rat glomerulus and tubule during recovery from renal ischemia. J Clin Invest 92: 2850-2857, 1993
11. Burtis WJ: Parathyroid hormone-related protein: Structure, function, and measurement [Review]. Clin Chem 38: 2171-2183, 1992
12. Mok LL, Nickols GA, Thompson JC, Cooper CW: Parathyroid hormone as a smooth muscle relaxant [Review]. Endocr Rev 10: 420-436, 1989
13. Fadda GZ, Akmal M, Premdas FH, Lipson LG, Massry SG: Insulin release from pancreatic islets: Effects of CRF and excess PTH. Kidney Int 33: 1066-1072, 1988
14. Soifer NE, Dee KE, Insogna KL, Burtis WJ, Matovcik LM, Wu TL, Milstone LM, Broadus AE, Philbrick WM, Stewart AF: Parathyroid hormone-related protein: Evidence for secretion of a novel mid-region fragment by three different cell types. J Biol Chem 267: 18236-18243, 1992
15. Orloff JJ, Ganz MB, Nathanson MH, Moyer MS, Kats Y, Mitnick M, Behal A, Gasalla-Herraiz J, Isales CM: A midregion hormone-related peptide mobilizes cytosolic calcium and stimulates formation of inositol triphosphate in a squamous carcinoma cell line. Endocrinology 137: 5376-5385, 1996
16. Wu TL, Vasavada RC, Yang K, Massfelder T, Ganz M, Abbas SK, Care AD, Stewart AF: Structural and physiologic characterization of the mid-region secretory species of parathyroid hormone-related protein. J Biol Chem 271: 24371-24381, 1996
17. Behar V, Pines M, Nakamoto C, Greenberg Z, Bisello A, Stueckle SM, Bessalle R, Usdin TB, Chorev M, Rosenblatt M, Suva LJ: The human PTH2 receptor: Binding and signal transduction properties of the stably expressed recombinant receptor. Endocrinology 137: 2748-2757, 1996
18. Usdin TB, Bonner TI, Harta G, Mezey E: Distribution of parathyroid hormone-2 receptor messenger ribonucleic acid in rat. Endocrinology 137: 4285-4297, 1996
19. 2+, vitamin D, and Pi in acid-base homeostasis [Review]. Am J Physiol 248: F739-F752, 1985
20. Caverzasio J, Bonjour JP: Inhibition of phosphate transport by parathyroid hormone in the opossum kidney cell line. Kidney Int 27: 111, 1985
21. Rizzoli CJ, Martin TJ, Bonjour JP: Tumoral synthetic parathyroid hormone related peptide inhibits amiloride-sensitive sodium transport in cultured renal epithelia. Pflügers Arch 413: 96-98, 1988
22. Rouleau MF, Warshawsky H, Goltzman D: Parathyroid hormone binding in vivo to renal, hepatic, and skeletal tissues of the rat using a radioautographic approach. Endocrinology 118: 919-931, 1986
23. Teitelbaum AP, Strewler GJ: Parathyroid hormone receptors coupled to cyclic adenosine monophosphate formation in an established renal cell line. Endocrinology 114: 980-985, 1984
24. Cole JA, Forte LR, Krause WJ, Thorne PK: Clonal sublines that are morphologically and functionally distinct from parental OK cells. Am J Physiol 256: F672-F679, 1989
25. 4Cl. J Clin Invest 84: 1767-1774, 1989
26. Wu S, Pirola CJ, Green J, Yamaguchi DT, Okano K, Jueppner H, Forrester JS, Fagin JA, Clemens TL: Effects of N-terminal, midregion, and C-terminal parathyroid hormone-related peptides on adenosine 3′,5′-monophosphate and cytoplasmic free calcium in rat aortic smooth muscle cells and UMR-106 osteoblast-like cells. Endocrinology 133: 2437-2444, 1993
27. 11 proteins in transfected Cos-7 cells. J Biol Chem 267: 1811-1817, 1992
28. Yasuda I, Kishimoto A, Tanaka S, Tominaga M, Sakurai A, Nishizuka Y: A synthetic peptide substrate for selective assay of protein kinase C. Biochem Biophys Res Commun 166: 1220-1227, 1990
29. Bringhurst FR, Juppner H, Guo J, Urena P, Potts JT Jr, Kronenberg HM, Abou-Samra AB, Segre GV: Cloned, stably expressed parathyroid hormone (PTH)/PTH-related peptide receptors activate multiple messenger signals and biological responses in LLC-PK1 kidney cells. Endocrinology 132: 2090-2098, 1993
30. Fujimori A, Miyauchi AA, Hruska KA, Martin KJ, Avioli LV, Civitelli R: Desensitization of calcium messenger system in parathyroid hormone-stimulated opossum kidney cells. Am J Physiol 264: E918-E924, 1993
31. Cano A, Presig P, Alpern RJ: Cyclic adenosine monophosphate acutely stimulates Na/H antiporter in OKP cells. J Clin Invest 92: 1632-1638, 1993
32. + exchange in opossum kidney cells: Polarity and mechanisms. Pflügers Arch 416: 615-623, 1990
33. + exchanger NHE3-3 isoform in renal (OK) cells via a dual signaling cascade involving protein kinase A and C. J Biol Chem 270: 20004-20010, 1995