A rapid dosimetric methacholine challenge in asthma diagnostics: A clinical study of 230 patients with dyspnoea, wheezing or a cough of unknown cause

Respiratory Medicine

Volumn 92, Issue 1, 1998, Pages 32-39

  Hedman, J ^a   Poussa, T ^b   Nieminen, M M ^c  

^a PÄIJÄT HÄME CENTRAL HOSPITAL   (Finland)

^b STAT Consulting   (Finland)

^c TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

METHACHOLINE;

ADULT; ARTICLE; ASTHMA; BAYES THEOREM; BRONCHUS HYPERREACTIVITY; CELL COUNT; CLINICAL TRIAL; COUGHING; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DOSIMETRY; DYSPNEA; EOSINOPHIL; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; MAJOR CLINICAL STUDY; MALE; PEAK EXPIRATORY FLOW; PRICK TEST; PRIORITY JOURNAL; PROVOCATION TEST; REGRESSION ANALYSIS; SMOKING; SPIROMETER; STATISTICS; SYMPTOM; WHEEZING;

EID: 0031888151     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0954-6111(98)90029-4     Document Type: Article

References (23)

1. Cockcroft DW, Killian DN, Mellon JJA, Hargreave FE. Bronchial reactivity to inhaled histamine: a method and clinical survey. Clin Allergy 1977; 7: 235-243.
2. Britton J, Mortagy A, Tattersfield AE. Histamine challenge testing: comparison of three methods. Thorax 1986; 41: 128-132.
3. Nieminen MM. Unimodal distribution of bronchial hyperresponsiveness to methacholine in asthmatic patients. Chest 1992; 102: 1537-1543.
4. Sovijärvi ARA, Malmberg LP, Reinikainen K, Rytilä P, Poppius H. A rapid dosimetric method with controlled tidal breathing for histamine challenge. Repeatability and distribution of bronchial reactivity in a clinical material. Chest 1993; 104: 164-170.
5. Sterk PJ, Fabbri LM, Quanjer PhH et al. Airway Responsiveness - Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults. Eur Respir J 1993; 6: 53-83.
6. Sont JK, van Krieken JHJM, Evertse CE, Hooijer R, Willems LNA, Sterk PJ. Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids. Thorax 1996; 51: 496-502.
7. Hedman J, Alanko K, Nieminen MM. Repeatability of a rapid dosimetric method for methacholine challenge using a pocket turbine spirometer for FEV1 measurements. Clin Physiol 1996; 16: 353-359.
8. Viljanen AA, Haittunen PK, Kreus KE, Viljanen BC. Spirometric studies in non-smoking, healthy adults. Scand J Clin Lab Invest 1982; 42 (Suppl. 159): 5-20.
9. Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC. Lung volumes and forced ventilatory flows. Eur Respir J 1993; 6 (Suppl. 16): 4-40.
10. American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Am Rev Respir Dis 1987; 136: 225-244.
11. Ulrik C.S. Peripheral eosinophil counts as a marker of disease activity in intrinsic and extrinsic asthma. Clin Exp Allergy 1995; 25: 820-827.
12. Nieminen MM, Lahdensuo A, Kellomäki L, Karvonen J. Muittari A. Methacholine bronchial challenge using a dosimeter with controlled tidal breathing. Thorax 1988; 43: 896-900.
13. Kennedy SM, Contreras GR. Measurement of non-specific bronchial responsiveness in epidemiologic studies: methacholine challenge testing in the field. Occupational Med 1993; 8: 303-321.
14. Perpina M, Pellicer C, de Diego A, Compte L, Macian V. Diagnostic value of the bronchial provocation test with methacholine in asthma. A Bayesian analysis approach. Chest 1993; 104: 149-154.
15. Knottnerus JA, Leffers P. The influence of referral patterns on the characteristics of diagnostic tests. J Clin Epidemiol 1992; 45: 1143-1154.
16. Popa V, Singleton J. Provocation dose and discriminant analysis in histamine bronchoprovocation. Are the current predictive data satisfactory? Chest 1988; 94: 466-475.
17. Neukirch F, Liard R, Segala C, Korobaeff M, Henry C, Cooreman J. Peak expiratory flow variability and bronchial responsiveness to methacholine. An epidemiologic study of 117 workers. Am Rev Respir Dis 1992; 146: 71-75.
18. Sears MR, Burrows B, Herbison GP, Holdaway MD, Flannery EM. Atopy in childhood. II. Relationship to airway responsiveness, hay fever and asthma. Clin Exp Allergy 1993; 23: 949-956.
19. Postma DS, Bleecker ER, Amelung PJ et al Genetic susceptibility to asthma-bronchial hyperresponsiveness coinherited with a major gene for atopy. N Engl J Med 1995; 333: 894-900.
20. Cockcroft DW, Berscheid BA, Murdock BSN. Unimodal distribution of bronchial responsiveness to inhaled histamine in a random population. Chest 1983; 83: 751-754.
21. Trigg CJ, Bennett JB, Tooley M, Sibbald B, D'Souza MFD, Davies RJ. A general practice based survey of bronchial hyperresponsiveness and its relation to symptoms, sex, age, atopy, and smoking. Thorax 1990; 45: 866-872.
22. Rijcken B, Schouten JP, Mensinga TT, Weiss ST, de Vries K, van der Lende R. Factors associated with bronchial responsiveness to histamine in a population sample of adults. Am Rev Respir Dis 1993; 147: 1447-1453.
23. Annema JT, Sparrow D, OConnor GT et al. Chronic respiratory symptoms and airway responsiveness to methacholine are associated with eosinophilia in older men: The Normative Aging Study. Ew Respir J 1995; 8: 62-69.