Run-down of the cardiac L-type Ca2+ channel: Partial restoration of channel activity in cell-free patches by calpastatin

Pflugers Archiv European Journal of Physiology

Volumn 435, Issue 3, 1998, Pages 344-349

  Kameyama, Masaki ^a   Kameyama, Asako ^a   Takano, Emiko ^b   Maki, Masatoshi ^c  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b Division of Pediatrics   (Japan)

^c NAGOYA UNIVERSITY   (Japan)

Author keywords

Calcium channel; Calpastatin; Cardiac myocyte; Cytoplasm; Patch clamp; Run down

Indexed keywords

ADENOSINE TRIPHOSPHATE; BENZAMIDINE; BENZYLSULFONYL FLUORIDE; CALCIUM; CALCIUM CHANNEL; CALPASTATIN; IODOACETAMIDE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOPLASM; HEART MUSCLE CELL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM CHANNELS; CALCIUM-BINDING PROTEINS; CALPAIN; CATTLE; CYTOPLASM; ERYTHROCYTES; GUINEA PIGS; HEART VENTRICLES; HUMANS; MOLECULAR WEIGHT; MUSCLE, SKELETAL; MYOCARDIUM; ORGAN SPECIFICITY; PATCH-CLAMP TECHNIQUES; RABBITS; RECOMBINANT PROTEINS; SPECIES SPECIFICITY; SWINE;

EID: 0031887141     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240050521     Document Type: Article

References (31)

1. Armstrong DL, Eckert R (1987) Voltage-dependent calcium channels that must be phosphorylated to respond to membrane depolarization. Proc Natl Acad Sci USA 84:2518-2522
2. Asada K, Ishino Y, Shimada M, Shimojo T, Endo M, Kimizuka F, Kato I, Maki M, Hatanaka M, Murachi T (1989) cDNA cloning of human calpastatin: sequence homology among human, pig, and rabbit calpastatins. J Enzyme Inhib 3:49-56
3. Belles B, Malecot CO, Hescheler J, Trautwein W (1988) "Run-down" of the Ca current during long whole-cell recordings in guinea-pig heart cells: role of phosphorylation and intracellular calcium. Pflügers Arch 411:353-360
4. Belles B, Hescheler J, Trautwein W, Blomgren K, Karlsson JO (1988) A possible physiological role of the Ca-dependent protease calpain and its inhibitor calpastatin on the Ca current in guinea pig myocytes. Pflügers Arch 412:554-556
5. 2+ channels in guinea pig myocytes. Pflügers Arch 398:284-297
6. Chad JE, Eckert R (1985) An enzymatic mechanism for calcium current inactivation in dialyzed Helix neurones. J Physiol (Lond) 378:31-51
7. Doroshenko PA, Kostyuk PG, Martynyuk AE, Kursky MD, Vorobetz ZD (1984) Intracellular protein kinase and calcium inward currents in perfused neurones of the snail Helix pomatia. Neuroscience 11:263-267
8. Emori Y, Kawasaki H, Imajoh S, Imahori K, Suzuki K (1987) Endogenous inhibitor for calcium-dependent cysteine protease contains four internal repeats that could be responsible for its multiple reactive sites. Proc Natl Acad Sci USA 84:3590-3594
9. Fenwick EM, Marty A, Neher E (1982) Sodium and calcium channels in bovine chromaffin cells. J Physiol (Lond) 331: 599-535
10. Hagiwara S, Byerly L (1983) The calcium channel. Trends Neurosci 6:189-193
11. Imajoh S, Kawasaki H, Emori Y, Suzuki K (1987) Calcium-activated neutral protease inhibitor from rabbit erythrocytes lacks the N-terminal region of the liver inhibitor but retains three inhibitory units. Biochem Biophys Res Commun 146:630-637
12. Kameyama M, Kameyama A, Nakayama T, Kaibara M (1988) Tissue extract recovers cardiac calcium channels from 'run-down'. Pflügers Arch 412:328-330
13. 2+ channel: characterization and restoration of channel activity by cytoplasmic factors. Pflügers Arch 433:547-556
14. Kostyuk PG (1984) Intracellular perfusion of nerve cells and its effects on membrane currents. Physiol Rev 64:435-454
15. Lee WJ, Hatanaka M, Maki M (1992) Multiple forms of rat calpastatin cDNA in the coding region of functionally unknown amino-terminal domain. Biochim Biophys Acta 1129:251-253
16. Lee WJ, Ma H, Takano E, Yang HQ, Hatanaka M, Maki M (1992) Molecular diversity in ammo-terminal domains of human calpastatin by exon skipping. J Biol Chem 267:8437-8442
17. McDonald TF, Pelzer S, Trautwein W, Pelzer D (1994) Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells. Physiol Rev 74:365-507
18. Melloni E, Salamino F, Sparatore B (1992) The calpain-calpastatin system in mammalian cells: properties and possible functions. Biochimie 74:217-223
19. Murachi T (1989) Intracellular regulatory system involving calpain and calpastatin. Biochem Int 18:263-294
20. Nilius B, Hess P, Lansmann JB, Tsien RW (1985) A novel type of cardiac calcium channel in ventricular cells. Nature 316:443-446
21. Ono K, Fozzard HA (1992) Phosphorylation restores activity of L-type calcium channels after rundown in inside-out patches from rabbit cardiac cells. J Physiol (Lond) 454:387-404
22. Romanin C, Grosswagen P, Schindler H (1991) Calpastatin and nucleotides stabilize cardiac calcium channel activity in excised patches. Pflügers Arch 418:86-92
23. Sakmann B, Neher E (eds) (1995) Single-channel recording (2nd ed). Plenum, New York, p 700
24. 2+ channel run-down cannot be mimicked by sythetic calpain inhibitors. Pflügers Arch 429:503-510
25. Suzuki K, Imajoh S, Emori Y, Kawasaki H, Minami Y, Ohno S (1988) Regulation of activity of calcium activated neutral protease. Adv Enzyme Regul 27:153-169
26. Takano E, Murachi T (1982) Purification and some properties of human erythrocyte calpastatin. J Biochem (Tokyo) 92: 2021-2028
27. Takano E, Kitahara A, Sasaki T, Kannagi R, Murachi T (1986) Two different molecular species of pig calpastatin. Structural and functional relationship between 107 kDa and 68 kDa molecules. Biochem J 235:97-102
28. Takano E, Maki M, Mori H, Hatanaka M, Marti T, Titani K, Kannagi R, Ooi T, Murachi T (1988) Pig heart calpastatin: identification of repetitive domain structures and anomalous behavior in polyacrylamide gel electrophoresis. Biochemistry 27:1964-1972
29. Towbin H, Staehelin T, Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76:4350-4354
30. Yazawa K, Kaibara M, Ohara M, Kameyama M (1990) An improved method for isolating cardiac myocytes useful for patchclamp studies. Jpn J Physiol 40:157-163
31. 2+ channel activity in a mechanism independent of protein phosphorylation. Pflügers Arch 433:557-562