β-Lactams SB 212047 and SB 216754 are irreversible, time-dependent inhibitors of coenzyme A-independent transacylase

Molecular Pharmacology

Volumn 53, Issue 2, 1998, Pages 322-329

  Winkler, James D ^a   Sung, Chiu Mei ^a   Chabot Flecher, Marie ^a   Griswold, Don E ^a   Marshall, Lisa A ^a   Chilton, Floyd H ^b   Bondinell, William ^a   Mayer, Ruth J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (2 ISOBUTENYLOXY) 3 TRIPHENYLMETHYLAMINO 2 AZETIDINONE; 6 BROMO 6 [HYDROXY(1 METHYL 1,2,3 TRIAZOL 4 YL)METHYL]PENICILLANIC ACID 4 METHOXYBENZYL ESTER; ACYLTRANSFERASE INHIBITOR; BETA LACTAM DERIVATIVE; ICOSANOID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARACHIDONIC ACID METABOLISM; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG ACTIVITY; DRUG MECHANISM; EDEMA; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; ICOSANOID METABOLISM; INFLAMMATORY INFILTRATE; MALE; MONOCYTE; MOUSE; NONHUMAN; OTITIS; PRIORITY JOURNAL; TOPICAL DRUG ADMINISTRATION;

EID: 0031886941     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.53.2.322     Document Type: Article

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