Synthesis and structure-activity relationship of 3-substituted benzamide, benzo[b]furan-7-carboxamide, 2,3-dihydrobenzo[b]furan-7- carboxamide, and indole-5-carboxamide derivatives as selective serotonin 5- HT4 receptor agonists

Chemical and Pharmaceutical Bulletin

Volumn 46, Issue 1, 1998, Pages 42-52

  Kakigami, Takuji ^a   Usui, Toshinao ^a   Tsukamoto, Katsura ^a   Kataoka, Tadashi ^b  

^a SANWA KAGAKU KENKYUSHO CO LTD   (Japan)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

2,3 dihydrobenzo b furan 7 carboxamide; Benzo b furan 7 carboxamide; Serotonin 5 HT4 agonistic activity; Structure activity relationship

Indexed keywords

8 AMINO 7 CHLORO 1,4 BENZODIOXAN 5 CARBOXYLIC ACID 1 BUTYL 4 PIPERIDINYLMETHYL ESTER; AMIDE; BENZAMIDE DERIVATIVE; BENZOFURAN DERIVATIVE; CISAPRIDE; DIHYDROBENZOFURAN DERIVATIVE; METOCLOPRAMIDE; SEROTONIN AGONIST;

ARTICLE; DRUG ACTIVITY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; LACTATION; NONHUMAN; PROLACTIN BLOOD LEVEL; STOMACH MOTILITY; STRUCTURE ACTIVITY RELATION;

EID: 0031886715     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.46.42     Document Type: Article

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