메뉴 건너뛰기




Volumn 38, Issue 2 SUPPL., 1998, Pages

Preclinical enantioselective pharmacology of (R)- and (S)- ketorolac

Author keywords

[No Author keywords available]

Indexed keywords

DELTA OPIATE RECEPTOR; IBUPROFEN; KAPPA OPIATE RECEPTOR; KETOPROFEN; KETOROLAC; LIPOXYGENASE; MORPHINE SULFATE; MU OPIATE RECEPTOR; NORADRENALIN; OPIATE RECEPTOR; PROSTAGLANDIN SYNTHASE INHIBITOR; SEROTONIN RECEPTOR;

EID: 0031886250     PISSN: 00912700     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1552-4604.1998.tb04414.x     Document Type: Article
Times cited : (24)

References (34)
  • 1
    • 0024948937 scopus 로고
    • Enantioselective aspects of drug action and disposition: Therapeutic pitfalls
    • Jamali F, Mehvar R, Pasutto FM: Enantioselective aspects of drug action and disposition: Therapeutic pitfalls. J Pharm Sci 1989;78:695-715.
    • (1989) J Pharm Sci , vol.78 , pp. 695-715
    • Jamali, F.1    Mehvar, R.2    Pasutto, F.M.3
  • 2
    • 0023881364 scopus 로고
    • Pharmacokinetics of enantiomers of chiral non-steroidal anti-inflammatory drugs
    • Jamali F: Pharmacokinetics of enantiomers of chiral non-steroidal anti-inflammatory drugs. Eur J Drug Metab Pharmacokinet 1989;13:1-9.
    • (1989) Eur J Drug Metab Pharmacokinet , vol.13 , pp. 1-9
    • Jamali, F.1
  • 3
    • 0023835819 scopus 로고
    • The metabolic chiral inversion and dispositional enantioselectivity of the 2-arylpropionic acids and their biological consequences
    • Caldwell J, Hutt AJ, Fournel-Gigleux S: The metabolic chiral inversion and dispositional enantioselectivity of the 2-arylpropionic acids and their biological consequences. Biochem Pharmacol 1988;37:105-114.
    • (1988) Biochem Pharmacol , vol.37 , pp. 105-114
    • Caldwell, J.1    Hutt, A.J.2    Fournel-Gigleux, S.3
  • 4
    • 0023598323 scopus 로고
    • The inhibitory activities of 480156-S and its related compounds on prostaglandin synthase
    • Yamaguchi T, Hirose K, Nakamura Y, Sugebo G: The inhibitory activities of 480156-S and its related compounds on prostaglandin synthase. Folia Pharmacol Jpn 1987;90:295-302.
    • (1987) Folia Pharmacol Jpn , vol.90 , pp. 295-302
    • Yamaguchi, T.1    Hirose, K.2    Nakamura, Y.3    Sugebo, G.4
  • 5
    • 0027132075 scopus 로고
    • Stereoselective cyclooxygenase inhibition in cellular models by the enantiomers of ketoprofen
    • Suesa N, Fernandez MF, Guiterrez M, Rufat MJ, Rotllan E, Calvo L, et al: Stereoselective cyclooxygenase inhibition in cellular models by the enantiomers of ketoprofen. Chirality 1993;5:589-595.
    • (1993) Chirality , vol.5 , pp. 589-595
    • Suesa, N.1    Fernandez, M.F.2    Guiterrez, M.3    Rufat, M.J.4    Rotllan, E.5    Calvo, L.6
  • 6
    • 2642671294 scopus 로고
    • Anti-inflammatory activity of S-(+)-ketoprofen in the carrageenan-induced paw edema of the rat
    • Ferrer X, Fernandez MF, Calvo L, et al: Anti-inflammatory activity of S-(+)-ketoprofen in the carrageenan-induced paw edema of the rat. Methods Find Exp Clin Pharmacol 1994;16(suppl 1):83-96.
    • (1994) Methods Find Exp Clin Pharmacol , vol.16 , Issue.1 SUPPL. , pp. 83-96
    • Ferrer, X.1    Fernandez, M.F.2    Calvo, L.3
  • 7
    • 0031887480 scopus 로고    scopus 로고
    • Clinical endoscopic evaluation of the gastroduodenal tolerance to (R)- Ketoprofen, (R)- flurbiprofen, racemic ketoprofen and paracetamol: A randomized, single-blind, placebo-controlled trial
    • Jerussi TP, Caubet JF, McCray JE, Handley DA: Clinical endoscopic evaluation of the gastroduodenal tolerance to (R)-ketoprofen, (R)-flurbiprofen, racemic ketoprofen and paracetamol: A randomized, single-blind, placebo-controlled trial. J Clin Pharmacol 1998;38(suppl):19S-24S.
    • (1998) J Clin Pharmacol , vol.38 , Issue.SUPPL.
    • Jerussi, T.P.1    Caubet, J.F.2    McCray, J.E.3    Handley, D.A.4
  • 8
    • 0028300256 scopus 로고
    • Antinociceptive actions of R(-)-flurbiprofen - A non-cyclooxygenase inhibiting 2 arylpropionic acid in rats
    • Geisslinger G, Ferreira SH, Menzel S, Schlott D, Brune K: Antinociceptive actions of R(-)-flurbiprofen - a non-cyclooxygenase inhibiting 2 arylpropionic acid in rats. Life Sci 1994;54:PL173-177.
    • (1994) Life Sci , vol.54
    • Geisslinger, G.1    Ferreira, S.H.2    Menzel, S.3    Schlott, D.4    Brune, K.5
  • 9
    • 0028149258 scopus 로고
    • Epimerization in humans and clinical implications of the use of racemates
    • Wechter WJ: Epimerization in humans and clinical implications of the use of racemates. J Clin Pharmacol 1994;34:1036-1042.
    • (1994) J Clin Pharmacol , vol.34 , pp. 1036-1042
    • Wechter, W.J.1
  • 11
    • 0029029296 scopus 로고
    • Inhibition of constitutive and inducible cyclooxygenase activity in human platelets and mononuclear cells by NSAIDs and COX-2 inhibitors
    • Grossman CJ, Wiseman J, Lucas FS, Trevethick MA, Birch PJ: Inhibition of constitutive and inducible cyclooxygenase activity in human platelets and mononuclear cells by NSAIDs and COX-2 inhibitors. Inflam Res 1995;44:253-257.
    • (1995) Inflam Res , vol.44 , pp. 253-257
    • Grossman, C.J.1    Wiseman, J.2    Lucas, F.S.3    Trevethick, M.A.4    Birch, P.J.5
  • 12
    • 0028867921 scopus 로고
    • Effects of flurbiprofen on pain-related chemosomatosensory-evoked potentials in human subjects
    • Lotsch J, Geisslinger G, Mohammadian P, Brune K, Kobal G: Effects of flurbiprofen on pain-related chemosomatosensory-evoked potentials in human subjects. Br J Clin Pharmacol 1995;40:339-346.
    • (1995) Br J Clin Pharmacol , vol.40 , pp. 339-346
    • Lotsch, J.1    Geisslinger, G.2    Mohammadian, P.3    Brune, K.4    Kobal, G.5
  • 13
    • 0021839067 scopus 로고
    • Synthesis and anti-inflammatory and analgesic activity of 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2a]pyrrole-1-carboxylic acids and related compounds
    • Muchowski JM, Unger S, Ackrell J, Cheung P, Cook J, et al: Synthesis and anti-inflammatory and analgesic activity of 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2a]pyrrole-1-carboxylic acids and related compounds. J Med Chem 1985;28:1037-1049.
    • (1985) J Med Chem , vol.28 , pp. 1037-1049
    • Muchowski, J.M.1    Unger, S.2    Ackrell, J.3    Cheung, P.4    Cook, J.5
  • 15
    • 0020286642 scopus 로고
    • The analgesic and anti-inflammatory profile of (±)-5-benzoyl-1,2-dihydro-3H-pyrrolo[1,2a]pyrrole-1-carboxylic acid (RS-37619)
    • Rooks WH, Tomolonis A, Maloney P, Wallack M, Schuler M: The analgesic and anti-inflammatory profile of (±)-5-benzoyl-1,2-dihydro-3H-pyrrolo[1,2a]pyrrole-1-carboxylic acid (RS-37619). Agents Actions 1982;12:684-690.
    • (1982) Agents Actions , vol.12 , pp. 684-690
    • Rooks, W.H.1    Tomolonis, A.2    Maloney, P.3    Wallack, M.4    Schuler, M.5
  • 18
    • 0026610297 scopus 로고
    • 3H]nisoxetine: A radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding
    • 3H]nisoxetine: A radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding. J Pharmacol Exp Ther 1992;260:427-436.
    • (1992) J Pharmacol Exp Ther , vol.260 , pp. 427-436
    • Tejani-Butt, S.M.1
  • 20
    • 0025966628 scopus 로고
    • Species differences in μ- and δ-opioid receptors
    • Yoburn BC, Lutfy K, Candido J: Species differences in μ-and δ-opioid receptors. Eur J Pharmacol 1991;193:105-108.
    • (1991) Eur J Pharmacol , vol.193 , pp. 105-108
    • Yoburn, B.C.1    Lutfy, K.2    Candido, J.3
  • 22
    • 0025757143 scopus 로고
    • 1-opioid receptor multiplicity in the guinea pig cerebellum
    • 1-opioid receptor multiplicity in the guinea pig cerebellum. Eur J Pharmacol 1991;207:135-141.
    • (1991) Eur J Pharmacol , vol.207 , pp. 135-141
    • Kinouchi, K.1    Pasternak, G.W.2
  • 23
    • 0027146692 scopus 로고
    • Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
    • Mitchell JA, Akarasereenont P, Thiemermann C, Flower RJ, Vane JR: Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci USA 1993;90:11693-11697.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11693-11697
    • Mitchell, J.A.1    Akarasereenont, P.2    Thiemermann, C.3    Flower, R.J.4    Vane, J.R.5
  • 24
    • 0018741634 scopus 로고
    • Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by dimethylsulfoxide
    • Collins SJ, Ruscetti FW, Gallagher RE, Gallo RC: Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by dimethylsulfoxide. J Exp Med 1979;149:969-974.
    • (1979) J Exp Med , vol.149 , pp. 969-974
    • Collins, S.J.1    Ruscetti, F.W.2    Gallagher, R.E.3    Gallo, R.C.4
  • 25
    • 0026343741 scopus 로고
    • Translocation of HL-60 cell 5-lipoxygenase
    • Kargman S, Prasit P, Evans JF: Translocation of HL-60 cell 5-lipoxygenase. J Biol Chem 1991;266:23745-23752.
    • (1991) J Biol Chem , vol.266 , pp. 23745-23752
    • Kargman, S.1    Prasit, P.2    Evans, J.F.3
  • 26
    • 0024388901 scopus 로고
    • Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate
    • Tayeh MA, Marletta MA: Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate. J Biol Chem 1989;264:19654-19658.
    • (1989) J Biol Chem , vol.264 , pp. 19654-19658
    • Tayeh, M.A.1    Marletta, M.A.2
  • 27
    • 0025750850 scopus 로고
    • Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured bovine aortic endothelial cells
    • Pollock JS, Fostermann U, Mitchell JA, Warner TD, Schmidt HHH, Nakane M, et al: Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured bovine aortic endothelial cells. Proc Natl Acad Sci USA 1991;88:10480-10484.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 10480-10484
    • Pollock, J.S.1    Fostermann, U.2    Mitchell, J.A.3    Warner, T.D.4    Schmidt, H.H.H.5    Nakane, M.6
  • 28
    • 0025191219 scopus 로고
    • Isolation of nitric oxide synthase, a calmodulin requiring enzyme
    • Bredt DS, Snyder SH: Isolation of nitric oxide synthase, a calmodulin requiring enzyme. Proc Natl Acad Sci USA 1990; 87:682-685.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 682-685
    • Bredt, D.S.1    Snyder, S.H.2
  • 30
    • 0028867921 scopus 로고
    • Effects of flurbiprofen enantiomers on pain-related chemo-somatosensory evoked potentials in human subjects
    • Lotsch J, Geisslinger G, Mahammadian P, Brune, Kobal G: Effects of flurbiprofen enantiomers on pain-related chemo-somatosensory evoked potentials in human subjects. Br J Clin Pharmacol 1995;40:339-346.
    • (1995) Br J Clin Pharmacol , vol.40 , pp. 339-346
    • Lotsch, J.1    Geisslinger, G.2    Mahammadian, P.3    Brune4    Kobal, G.5
  • 31
    • 2642642278 scopus 로고    scopus 로고
    • R(-) but not the S(+)-ketoprofen attenuates neurogenic inflammation within the rat meninges
    • Limmroth V, Yu X, Moskowitz MA: R(-) but not the S(+)-ketoprofen attenuates neurogenic inflammation within the rat meninges. Pharmacologist 1997;39:81.
    • (1997) Pharmacologist , vol.39 , pp. 81
    • Limmroth, V.1    Yu, X.2    Moskowitz, M.A.3
  • 33
    • 0029953234 scopus 로고
    • Protective activity of ketoprofen lysine salt against the pulmonary effects induced by bradykinin in guinea-pigs
    • Daffonchio L, Rossoni G, Clavenna G, Omini C, Berti F: Protective activity of ketoprofen lysine salt against the pulmonary effects induced by bradykinin in guinea-pigs. Inflam Res 1995;45:259-264.
    • (1995) Inflam Res , vol.45 , pp. 259-264
    • Daffonchio, L.1    Rossoni, G.2    Clavenna, G.3    Omini, C.4    Berti, F.5
  • 34
    • 0030469843 scopus 로고    scopus 로고
    • Pharmacodynamics and pharmacokinetics of the profens: Enantioselectivity, clinical implications, and special reference to (S+)-ibuprofen
    • Evans AM: Pharmacodynamics and pharmacokinetics of the profens: Enantioselectivity, clinical implications, and special reference to (S+)-ibuprofen. J Clin Pharmacol 1996;36:7S-15S.
    • (1996) J Clin Pharmacol , vol.36
    • Evans, A.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.