Norepinephrine transporters in rat placenta labeled with [3H]nisoxetine

Journal of Pharmacology and Experimental Therapeutics

Volumn 284, Issue 2, 1998, Pages 736-743

  Shearman, Lauren P ^a,b   Meyer, Jerrold S ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA (4 IODOPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; AMFEBUTAMONE; CARRIER PROTEIN; CITALOPRAM; COCAINE; COCAINE DERIVATIVE; DESIPRAMINE; DIFLUOROPINE; DOPAMINE; MONOAMINE OXIDASE INHIBITOR; NISOXETINE; NOMIFENSINE; NORADRENALIN; RADIOLIGAND; UNCLASSIFIED DRUG; VANOXERINE; ZIMELDINE;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING COMPETITION; BINDING KINETICS; CATECHOLAMINE UPTAKE; FEMALE; LIGAND BINDING; NONHUMAN; PLACENTA; PRIORITY JOURNAL; PROTEIN BINDING; RAT; TISSUE DISTRIBUTION;

ANIMALS; AUTORADIOGRAPHY; BINDING, COMPETITIVE; CARRIER PROTEINS; FLUOXETINE; NEUROTRANSMITTER UPTAKE INHIBITORS; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PIPERAZINES; PLACENTA; RATS; RATS, SPRAGUE-DAWLEY; SYMPORTERS;

EID: 0031886152     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. Ahmed MS, Zhou D-H, Cavinato AG and Maulik D (1989) Opioid binding properties of the purified kappa receptor from human placenta. Life Sci 44:861-871.
2. Azoui R, Cuche J-L, Renaud J-F, Safar M and Dagher G (1996) A dopamine transporter in human erythrocytes: Modulation by insulin. Exp Physiol 81:421-434.
3. Belisle S, Petit A, Gallo-Payet N, Bellabarba D, Lehoux J-G and Lemaire S (1988) Functional opioid receptor sites in human placentas. J Clin Endocrinol Metab 66:283-289.
4. Bradford MM (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
5. Bzoskie L, Blount L, Kashiwai K, Humme J and Padbury JF (1997) The contribution of transporter-dependent uptake to fetal catecholamine clearance. Biol Neonate 71:102-110.
6. Bzoskie L, Blount L, Kashiwai K, Tseng Y-T, Hay WW Jr and Padbury JF (1995) Placental norepinephrine clearance: In vivo measurement and physiological role. Am J Physiol 269:E145-E149.
7. Chen CH, Klein DC and Robinson JC (1974) Catechol-O-methyltransferase in rat placenta, human placenta, and choriocarcinoma grown in culture. J Reprod Fert 39:407-410.
8. Collins LM and Meyer JS (1996) Prenatal cocaine alters dopamine transporter binding in postnatal day 10 rat striatum. Synapse 23:335-343.
9. Davies J and Glasser SR (1968) Histological and fine structural observations on the placenta of the rat. Acta Anat 69:542-608.
10. DeMaria FJ (1964) Placental monoamine oxidase in normal and toxemic patients. Am J Obstet Gynecol 88:490-494.
11. Di Chiara G, Tanda GL, Frau R and Carboni E (1992) Heterologous monoamine reuptake: Lack of transmitter specificity of neuron-specific carriers. Neurochem Int 20: suppl., 231S-235S.
12. Dyer DC (1970) The pharmacology of isolated sheep umbilical cord blood vessels. J Pharmacol Exp Ther 175:565-570.
13. Enders AC (1964) A comparative study of the fine structure of the trophoblast in several hemochorial placentas. Am J Anat 116:29-68.
14. Fant ME and Harbison RD (1981) Syncytiotrophoblast membrane vesicles: A model for examining the human placental cholinergic system. Teratology 24:187-199.
15. 3H]-dopamine uptake by human lymphocytes: Correlates with serotonin transporter activity. Pharmacology 48:320-327.
16. Flynn DD, Sanchez-Ramos L and Mash DC (1993) Perinatal cocaine exposure alters sigma binding site density in the placenta. Res Commun Subst Abuse 14:17-36.
17. Fox SB and Khong TY (1990) Lack of innervation of human umbilical cord: An immunohistological and histochemical study. Placenta 11:59-62.
18. Ganapathy V and Leibaeh FH (1995) Placental biogenic amines and their transporters, in Placental Toxicology (Sastry BVR, ed) pp 161-174, CRC Press, Boca Raton FL.
19. Gilbert WM, Lafferty CM, Benirschke K and Resnik R (1990) Lack of specific placental abnormality associated with cocaine use. Am J Obstet Gynecol 163:998-999.
20. Grullon K, Macobs MM, Li SX and Illsley NP (1995) Beta-adrenergic regulation of cyclic AMP synthesis in cultured human syncytiotrophoblast. Placenta 16:589-597.
21. Jayanthi LD, Prasa PD, Ramamoorthy S, Mahesh VB, Leibach FH and Ganapathy V (1993) Sodium- and chloride-dependent, cocaine-sensitive, high-affinity binding of nisoxetine to the human placental norepinephrine transporter. Biochemistry 32:12178-12185.
22. Jones CT (1980) Circulating catecholamines in the fetus: Their origin, actions and significance, in Biogenic Amines in Development (Parvez H and Parvez S, eds) pp 63-86, Elsevier/North-Holland Biomedical Press, Amsterdam.
23. Leiser R and Kaufmann P (1994) Placental structure: In a comparative aspect. Exp Clin Endocrinol 102:122-134.
24. Maigaard S, Forman A and Andersson K-E (1986) Relaxant and contractile effects of some amines and prostanoids in myometrial and vascular smooth muscle within the human uteroplacental unit. Acta Physiol Scand 128:33-40.
25. Matsubara S, Tamada T and Saito T (1987) Ultracytochemical localizations of adenylyl cyclase, guanylate cyclase and cyclic 3′-5′-nucleotide phosphodiesterase activity on the trophoblast in the human placenta: Direct histochemical evidence. Histochemistry 87:505-509.
26. Meltzer PC, Liang AY and Madras BK (1994) The discovery of an unusually selective and novel cocaine analog, difluoropine: Synthesis and inhibition of binding at cocaine recognition sites. J Med Chem 37:2001-2010.
27. Meyer JS, Shearman LP, Collins LM and Maguire RL (1993) Cocaine binding sites in fetal rat brain: Implications for prenatal cocaine action. Psychopharmacology 112:445-451.
28. Morgan CD, Sandler M and Panigel M (1972) Placental transfer of catecholamines in vitro and in vivo. Am J Obstet Gynecol 112:1068-1075.
29. Nair X and Dyer DC (1974) Responses of guinea pig umbilical vasculature to vasoactive drugs. Eur J Pharmacol 27:294-304.
30. Nulsen JC, Woolkalis MJ, Kopf GS and Strauss JF III (1988) Adenylate cyclase in human cytotrophoblasts: Characterization and its role in modulating human chorionic gonadotropin secretion. J Clin Endocrinol Metab 66:258-265.
31. Oike N, Iwashita M, Muraki T, Nomoto T, Takeda Y and Sakamoto S (1989) Effect of adrenergic agonists on human chorionic gonadotropin release by human trophoblast cells obtained from first trimester placenta. Horm Metab Res 22:188-191.
32. Pacholczyk T, Blakely RD and Amara SG (1991) Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter. Nature 350:350-354.
33. Perry BD (1988) Placental and blood element neurotransmitter receptor regulation in humans: Potential models for studying neurochemical mechanisms underlying behavioral teratology, in Biochemical Basis of Functional Neuroteratology (Boer GJ, Feenstra MGP, Mirmiran M, Swaab DF and Van Haaren F, eds) pp 189-205, Elsevier, Amsterdam.
34. 2-dopamine receptors in human term placenta. J Recept Res 10:205-215.
35. Ramamoorthy JD, Ramamoorthy S, Leibach FH and Ganapathy V (1995a) Human placental monoamine transporters as targets for amphetamines. Am J Obstet Gynecol 173:1782-1787.
36. Ramamoorthy JD, Ramamoorthy S, Mahesh VB, Leibach FH and Ganapathy V (1995b) Cocaine-sensitive σ-receptor and its interaction with steroid hormones in the human placental syncytiotrophoblast and in choriocarcinoma cells. Endocrinology 136:924-932.
37. Ramamoorthy S, Leibach FH, Mahesh VB and Ganapathy V (1992) Active transport of dopamine in human placental brush-border membrane vesicles. Am J Physiol 262:C1189-C1196.
38. Ramamoorthy S, Prasa PD, Kulanthaivel P, Leibach FH, Blakely RD and Ganapathy V (1993) Expression of a cocaine-sensitive norepinephrine transporter in the human placental syncytiotrophoblast. Biochemistry 32:1346-1353.
39. Ramsey EM (1962) Circulation in the intervillous space of the primate placenta. Am J Obstet Gynecol 84:1649-1663.
40. Reviriego J, Fernandez-Alfonso MS and Marín J (1990) Actions of vasoactive drugs on human placental vascular smooth muscle. Gen Pharmacol 21:719-727.
41. Rhodes KJ, Meiners KA and Rosene DL (1993) A novel hinge system and incubation chamber for emulsion-coated coverslip autoradiography. J Histochem Cytochem 41:1419-1427.
42. 3H]GBR-12935:binding characteristics. Brain Res 540:1-13.
43. Saarikoski S (1974) Fate of noradrenaline in the human foetoplacental unit. Acta Physiol Scand Suppl 421:1-82.
44. Salhab AS, DeVane CL, Medrano T, Buhi WC, Tebbett IR and Shiverick KT (1994) Fetoplacental growth and placental protein synthesis in rats after chronic maternal cocaine administration. J Pharmacol Exp Ther 270:392-398.
45. Sandier M, Ruthven CRJ, Contractor SF, Wood C, Booth RT and Pinkerton JHM (1963) Transmission of noradrenaline across the human placenta. Nature 197:598.
46. Schocken DD, Caron MG and Lefkowitz RJ (1980) The human placenta: A rich source of β-adrenergic receptors: Characterization of the receptors in particulate and solubilized preparations. J Clin Endocrinol Metab 50:1082-1088.
47. 125I]RTI-55-labeled cocaine binding sites in fetal and adult brain. J Pharmacol Exp Ther 277:1770-1783.
48. Simone C, Byrne BM, Derewlany LO and Keren G (1996) Cocaine inhibits hCG secretion by the human term placental cotyledon perfused in vitro. Life Sci 58:PL63-66.
49. Soares MJ, Faria TN, Roby KF and Deb S (1991) Pregnancy and the prolactin family of hormones: Coordination of anterior pituitary, uterine, and placental expression. Endocr Rev 12:402-423.
50. Sodha RJ, Proegler M and Schneider H (1984) Transfer and metabolism of norepinephrine studied from maternal-to-fetal and fetal-to-maternal sides in the in vitro perfused human placental lobe. Am J Obstet Gynecol 148:474-481.
51. Strauss JF III, Kido S, Sayegh R, Sakuragi N and Ga°fvels ME (1992) The cAMP signalling system and human trophoblast function. Placenta 13:389-403.
52. 3H]Nisoxetine: A radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding. J Pharmacol Exp Ther 260:427-436.
53. Thomas SA, Matsumoto AM and Palmiter RD (1995) Noradrenaline is essential for mouse fetal development. Nature 374:643-646.
54. 3H]-spiperone. J Recept Res 14:11-22.
55. Walker DW and McLean JR (1971) Absence of adrenergic nerves in the human placenta. Nature 229:344-345.
56. Whitsett JA, Johnson CL and Hawkins K (1979) Differences in localization of insulin receptors and adenylate cyclase in the human placenta. Am J Obstet Gynecol 133:204-207.
57. Whitsett JA, Johnson CL, Noguchi A, Darovec-Beckerman C and Costello M (1980) β-Adrenergic receptors and catecholamine-sensitive adenylate cyclase of the human placenta. J Clin Endocrinol Metab 50:27-32.
58. Wong DT and Bymaster FP (1976) Effect of nisoxetine on uptake of catecholamines in synaptosomes isolated from discrete regions of rat brain. Biochem Pharmacol 25:1979-1983.
59. Wong DT, Threlkeld PG, Best KL and Bymaster FP (1982) A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat brain. J Pharmacol Exp Ther 222:61-65.
60. 3H]Opioid receptor labeling in mounted tissue sections. Brain Res 179:255-270.