Diabetic nephropathy is associated with AGT polymorphism T235: Results of a family-based study

Hypertension

Volumn 31, Issue 2, 1998, Pages 627-631

  Rogus, John J ^a,b   Moczulski, Dariusz ^a,c   Freire, Maria Beatriz S ^a,c   Yang, Yadong ^a,c   Warram, James H ^a,c   Krolewski, Andrzej S ^a,c  

^a JOSLIN DIABETES CENTER   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Angiotensinogen; Diabetes, insulin dependent; Nephropathy, diabetic

Indexed keywords

ALLELE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DIAGNOSTIC APPROACH ROUTE; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY FAILURE; MALE; PRIORITY JOURNAL;

EID: 0031885616     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.31.2.627     Document Type: Article

References (22)

1. Quinn M, Angelico MC, Warram JH, Krolewski AS. Familial factors determine the development of diabetic nephropathy in patients with IDDM. Diabetologia. 1996;39:940-945.
2. Seaquist ER, Goetz FC, Rich SS, Barbosa J. Familial clustering of diabetic kidney disease: evidence for genetic susceptibility to diabetic nephropathy. N Engl J Med. 1989;320:1161-1165.
3. Borch-Johnsen K, Norgaard K, Hommel E, Mathiesen ER, Jensen JS, Deckert T, Parving HH. Is diabetic nephropathy an inherited complication? Kidney Int. 1992;41:719-722.
4. Viberti GC, Keen H, Wiseman MJ. Raised arterial pressure in parents of proteinuric insulin-dependent diabetics. Br Med J. 1987;295:515-517.
5. Krolewski AS, Canessa M, Warram JH, Laffel LMB, Christlieb AR, Knowler WC, Rand LI. Predisposition to hypertension and susceptibility to renal disease in insulin-dependent diabetes mellitus. N Engl J Med. 1988;318:140-145.
6. Jeunemaitre X, Soubrier F, Kotelevtsev YV, Lifton RP, Williams CS, Charru A, Hunt SC, Hopkins PN, Williams RR, Lalouel J-M, Corvol P. Molecular basis of human hypertension: role of angiotensinogen. Cell. 1992;71:169-180.
7. Caulfield M, Lavender P, Farral M, Path MRC, Munroe P, Lawson M, Turner P, Clark AJL. Linkage of the angiotensinogen gene to essential hypertension. N Engl J Med. 1994;330:1629-1633.
8. Brown MJ, Clayton D. Linkage of the angiotensinogen gene to essential hypertension. N Engl J Med. 1994;331:1096. Letter.
9. Fogarty DG, Harron JC, Hughes AE, Nevin NC, Doherty CC, Maxwell AP. A molecular variant of angiotensinogen is associated with diabetic nephropathy in IDDM. Diabetes. 1996;45:1204-1208.
10. Marre M, Jeunemaitre X, Gallois Y, Rodier M, Chatellier G, Sert C, Dusselier L, Kahal Z, Chaillous L, Halimi S, Muller A, Sackmann H, Bauduceau B, Bled F, Passa P, Alhenc-Gelas F. Contribution of genetic polymorphism in the renin-angiotensin system to the development of renal complications in insulin-dependent diabetes: Génétique de la Néphropathie Diabétique (GENEDIAB) study group. J Clin Invest. 1997; 99:1585-1595.
11. Tarnow L, Cambien F, Rossing P, Nielsen FS, Hansen BV, Ricard S, Poirier O, Parving H-H. Angiotensinogen gene polymorphisms in IDDM patients with diabetic nephropathy. Diabetes. 1996;45:367-369.
12. Ringel J, Beige J, Kunz R, Distler A, Sharma AM. Genetic variants of the renin-angiotensin system, diabetic nephropathy and hypertension. Diabetologia. 1997;40:193-199.
13. Chowdhury TA, Dronsfield MJ, Kumar S, Gough SLC, Gibson SP, Khatoon A, MacDonald F, Rowe BR, Dunger DB, Dean JD, Davies SJ, Webber J, Smith PR, Mackin P, Marshall SM, Adu D, Morris PJM, Todd JA, Barnett AH, Boulton AJM, Bain SC. Examination of two genetic polymorphisms within the renin-angiotensin system: no evidence for an association with nephropathy in IDDM. Diabetologia. 1996;39:1108-1114.
14. Schmidt S, Giebel R, Bergis KH, Strojek K, Grzeszczak W, Ganten D, Ritz E, and the Diabetic Nephropathy Study Group. Angiotensinogen gene M235T polymorphism is not associated with diabetic nephropathy. Nephrol Dial Transplant. 1996;11:1755-1761.
15. Spielman RS, McGinnis RB, Ewens WJ. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet. 1993;52:506-516.
16. Hopkins PN, Lifton RP, Hollenberg NK, Jeunemaitre X, Halloiun M-C, Skuppin J, Williams CS, Dluhy RG, Lalouel J-M, Williams RR, Williams GH. Blunted renal vascular response to angiotensin II is associated with a common variant of the angiotensinogen gene and obesity. J Hypertens. 1996;14:199-207.
17. Warram JH, Gearin G, Laffel L, Krolewski AS. Effect of duration of type I diabetes on the prevalence of stages of diabetic nephropathy defined by urinary albumin/creatinine ratio. J Am Soc Nephrol. 1996;7:930-937.
18. Doria A, Onuma T, Gearin G, Freire MBS, Warram J, Krolewski AS. Angiotensinogen polymorphism M235T, hypertension, and nephropathy in insulin-dependent diabetes. Hypertension. 1996;27:1134-1139.
19. Curtis D, Sham PC. A note on the application of the transmission disequilibrium test when a parent is missing. Am J Hum Genet. 1995;56:811-812. Letter.
20. 19a. Freire MBS, Ji L, Onuma T, Orban T, Warram J, Krolewski AS. Gender-specific association of M235T polymorphism in angiotensinogen gene and diabetic nephropathy in NIDDM. Hypertension. In press.
21. Jeunemaitre X, Inoue I, Williams C, Charru A, Tichet J, Powers M, Sharma AM, Gimenez-Roqueplo A-P, Hata A, Corvol P, Lalouel J-M. Haplotypes of angiotensinogen in essential hypertension. Am J Hum Genet. 1997;60:1448-1460.
22. Inoue I, Nakajima T, Williams CS, Quackenbush J, Puryear R, Powers M, Cheng T, Ludwig EH, Sharma AM, Hata A, Jeunemaitre X, Lalouel J-M. A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro. J Clin Invest. 1997;99:1786-1797.