Bisphosphonate maintains parathyroid hormone (1-34)-induced cortical bone mass and mechanical strength in old rats

Calcified Tissue International

Volumn 62, Issue 4, 1998, Pages 316-322

  Ejersted, C ^a   Oxlund, H ^a   Andreassen, T T ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Bisphosphonate; Cortical bone; Mechanical strength; Parathyroid hormone; Rats

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; PARATHYROID HORMONE; PHOSPHATE; RISEDRONIC ACID;

ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; BONE DENSITY; BONE MASS; BONE MINERALIZATION; BONE STRENGTH; CONTROLLED STUDY; CORTICAL BONE; DOSE RESPONSE; FEMUR; HORMONAL REGULATION; MORPHOMETRICS; NONHUMAN; OSTEOLYSIS; PRIORITY JOURNAL; RAT;

ANIMALS; BODY WEIGHT; BONE AND BONES; BONE DENSITY; DIPHOSPHONATES; EXERTION; FEMUR; HUMANS; MALE; PARATHYROID HORMONE; PARATHYROID HORMONE-RELATED PROTEIN; PEPTIDE FRAGMENTS; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; STRESS; TENSILE STRENGTH;

EID: 0031885266     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002239900438     Document Type: Article

References (24)

1. Oxlund H, Ejersted C, Andreassen TT, Tørring O, Nilsson MHL (1993) Parathyroid hormone (1-34) and (1-84) stimulate cortical bone formation both from periosteum and endosteum. Calcif Tissue Int 53:394-399
2. Ejersted C, Andreassen TT, Oxlund H, Jørgensen PH, Bak B, Häggblad J, Tørring O, Nilsson MHL (1993) Human parathyroid hormone (1-34) and (1-84) increase the mechanical strength and thickness of cortical bone in rats. J Bone Miner Res 8:1097-1101
3. Ejersted C, Andreassen TT, Nilsson MHL, Oxlund H (1994) Human parathyroid hormone (1-34) increases bone formation and strength of cortical bone in aged rats. Eur J Endocrinol 130:201-207
4. Liu CC, Kalu DN (1990) Human parathyroid hormone-(1-34) prevents bone loss and augments bone formation in sexually mature ovariectomized rats. J Bone Miner Res 5:973-982
5. Wronski TJ, Yen C-F (1994) Anabolic effects of parathyroid hormone on cortical bone in ovariectomized rats. Bone 15:51-58
6. Baumann DB, Wronski TJ (1995) Response of cortical bone to antiresorptive parathyroid hormone in aged ovariectomized rats. Bone 12:247-253
7. Mosekilde L, Danielsen CC, Sogaard CH, McOsker JE, Wronski TJ (1995) The anabolic effect of parathyroid hormone on cortical bone mass, dimensions and strength-assessed in a sexually mature, ovariectomized rat model. Bone 16:223-230
8. Gunness-Hey M, Hock JM (1989) Loss of the anabolic effect of parathyroid hormone on bone after discontinuation of hormone in rats. Bone 10:447-452
9. Yamamoto N, Takahashi HE, Tanizawa T, Fujimoto R, Hara T, Tanaka S (1993) Maintenance of bone mass by physical exercise after discontinuation of intermittent hPTH(J-34) administration. Bone Miner 23:333-342
10. Yamamoto N, Takahashi HD, Tanizawa T, Endo N, Nishida S, Kinto N (1995) Discrepancy of response of hPTH administration and its withdrawal between trabecular and cortical bone sites in OVX rats. Bone 17:279S-283S
11. Takano Y, Tanizawa T, Mashiba T, Endo N, Nishida S, Takahashi HE (1996) Maintaining bone mass by bisphosphonate incadronate disodium (YM175) sequential treatment after discontinuation of intermittent human parathyroid hormone (1- 34) administration in ovariectomized rats. J Bone Miner Res 11:169-177
12. Andreassen TT, Jørgensen PH, Flyvbjerg A, Ørskov L, Oxlund H (1995) Growth hormone stimulates bone formation and strength of cortical bone in aged rats. J Bone Miner Res 10:1057-1067
13. Ejersted C, Andreassen TT, Oxlund H, Jørgensen PH, Bak B, Häggblad J, Tørring O, Nilsson MHL (1993) Human parathyroid hormone (1-34) and (1-84) increase the mechanical strength and thickness of cortical bone in rats. J Bone Miner Res 8:1097-1101
14. Danielsen CC, Mosekilde L, Andreassen TT (1992) Longterm effect of orchidectomy on cortical bone from rat femur: bone mass and mechanical properties. Calcif Tissue Int 50:169-174
15. Woessner JF Jr (1976) Determination of hydroxyproline in connective tissue. In: Hall DA (ed) The methology of connective tissue research. Joynson-Bruvers Ltd., Oxford, pp 227-233
16. Stoltz M, Furthmayr H, Timpl R (1973) Increased lysine hydroxylation in rat bone and tendon collagen and localization of the additional residues. Biochim Biophys Acta 310:461-468
17. Tang LY, Jee WS, Ke HZ, Kimmel DB (1992) Restoring and maintaining bone in osteopenic female rat skeleton: I. Changes in bone mass and structure. J Bone Miner Res 7:1093-1104
18. Jec WS, Ke HZ, Li XJ (1992) Loss of prostaglandin E2- induced extra cortical bone after its withdrawal in rats. Bone Miner 17:31-47
19. Hefti E, Trechsel U, Bonjour JP, Fleisch H, Schenk R (1982) Increase of whole-body calcium and skeletal mass in normal and osteoporotic adult rats treated with parathyroid hormone. Clin Sci 62:389-396
20. Jerome CP (1994) Anabolic effect of high doses of human parathyroid hormone (1-38) in mature intact female rats. J Bone Miner Res 9:933-942
21. Kimmel DB (1993) A paradigm for skeletal strength homeostasis. J Bone Miner Res 8(suppl):2:S515-S522
22. Turner CH, Burr DB (1993) Basic biomechanical measurements of bone: a tutorial. Bone 14:595-608
23. Toolan BC, Shea M, Myers ER, Borchers RE, Seedor JG, Quartuccio H, Rodan G, Hayes WC (1992) Effects of 4- amino-1-hydroxybutylidene bisphosphonate on bone biomechanics in rats. J Bone Miner Res 7:1399-1406
24. Mosekilde L, Danielsen CC, Knudsen UB (1993) The effect of aging and ovariectomy on the vertebral bone mass and biomechanical properties of mature rats. Bone 14:1-6